Hippo Signaling Current Events | Hippo Signaling News | 6
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A pathway towards cures for Parkinson`s and cancer
Researchers studying the Hedgehog signaling pathway have identified small molecules that could form the foundations of exciting new treatments for Parkinson's disease and certain cancers. New research published in Journal of Biology - the open access journal for exceptional research - has identified small molecules that are able to stimulate or... view more... (2002-11-01)
Protein helps immune cells to divide and conquer
Researchers at the University of California, San Diego School of Medicine have identified a key protein that is required for immune cells called B lymphocytes to divide and replicate themselves. The rapid generation of large numbers of these immune cells is critical to the body's antibody defense mechanism. view more (2009-03-09)
Calcium may be the key to understanding Alzheimer's disease
Researchers at the University of Pennsylvania School of Medicine have shown that mutations in two proteins associated with familial Alzheimer's disease disrupt the flow of calcium ions within neurons. The two proteins, called PS1 and PS2 (presenilin 1 and 2), interact with a calcium release channel in an intracellular cell compartment. view more (2008-07-21)
Study may explain exercise-induced fatigue in muscular dystrophies
A University of Iowa study suggests that the prolonged fatigue after mild exercise that occurs in people with many forms of muscular dystrophy is distinct from the inherent muscle weakness caused by the disease. view more (2008-10-27)
CU-Boulder study shows 53 million-year-old high Arctic mammals wintered in darkness
Ancestors of tapirs and ancient cousins of rhinos living above the Arctic Circle 53 million years ago endured six months of darkness each year in a far milder climate than today that featured lush, swampy forests. view more (2009-06-02)
Study finds foul owls use feces to show they are in fine feather
Some years ago, within the Department of Conservation Biology of the Estación Biológica de Doñana (EBD-Consejo Superior de Investigaciones Científicas; Seville, Spain), a recently established group (colloquially named the Night Ecology Group) started to explore the possibility of visual communication in crepuscular and... view more... (2008-08-20)
Researchers uncover mechanisms of common inherited mental retardation
Researchers at UT Southwestern Medical Center are uncovering how brain cells are affected in Fragile X syndrome, the most common cause of inherited mental retardation and the most common genetic cause of autism. view more (2008-01-09)
Developing cancer treatments directed at critical developmental pathway
Researchers from the University of Pennsylvania School of Medicine and colleagues discovered that the Notch signaling pathway, which determines the development of many cell types, and is also implicated in some cancers, is not universally essential for the maintenance of stem cells. view more (2008-04-11)
Penn study finds pro-death proteins required to regulate healthy immune function
Researchers at the University of Pennsylvania School of Medicine have found that proteins known to promote cell death are also necessary for the maturation and proliferation of immune cells. view more (2007-08-13)
Neural Stem Cells Are Long-Lived
New studies in mice have shown that immature stem cells that proliferate to form brain tissues can function for at least a year - most of the life span of a mouse - and give rise to multiple types of neural cells, not just neurons. view more (2005-10-06)
Unique dual target specificity of kinase inhibitor key for success against cancer
Scientists have identified a new molecule that inhibits proliferation of a broad range of lethal malignant glioma cells in vitro and in vivo. view more (2006-05-16)
The vasculature emerges as a potential therapeutic target in treating ADPKD liver cysts
As part of an effort to develop effective medical therapies that block the progression of liver cyst growth in patients with Autosomal Dominant Polycystic Kidney Disease (ADPKD), researchers at the University of Colorado Anschutz Medical Center have found that the liver cyst walls develop and maintain a vasculature as they grow out from the body... view more... (2009-09-24)
Brain size may depend upon how neural cells are cleaved
Howard Hughes Medical Institute researchers have discovered a novel way in which the brain size of developing mammals may be regulated. They have identified a signaling pathway that controls the orientation in which dividing neural progenitor cells are cleaved during development. view more (2005-07-15)
Research details how a virus hijacks cell signals to cause infection
A common virus that causes meningitis and heart inflammation takes a "back door" approach to evade natural barriers, then exploits biological signals to infect human cells. view more (2006-01-13)
New molecular regulators of hyperthyroidism and goiter
The thyroid gland has an important role in determining how much energy the body burns. Thyroid gland functions are regulated by a hormone known as thyroid-stimulating hormone (TSH). view more (2007-08-10)
OHSU School of Dentistry team discovers potential new target for treating craniofacial pain problems
Researchers at Oregon Health & Science University's School of Dentistry have uncovered an interaction between two proteins in the nerve cells that carry pain information from the head and neck to the brain. view more (2006-10-31)
Emory researchers identify signaling protein for multiple myeloma
Researchers at Emory University's Winship Cancer Institute are the first to discover a mechanism that plays a critical role in the multiple myeloma cell cycle and survival. view more (2007-09-11)
New target for heart failure therapy identified
A novel signaling pathway plays a significant role in the production of aldosterone, a hormone that promotes heart failure after a myocardial infarction, according to a study conducted by Thomas Jefferson University researchers. view more (2009-03-17)
Lipids play important role in nervous system development
Blocking a signaling lipid can keep nerves from developing the arm-like extensions they need to wire the body and may even cause neurons to die, researchers have found. view more (2005-10-25)
Researchers uncover details about how dietary restriction slows down aging
University of Washington scientists have uncovered details about the mechanisms through which dietary restriction slows the aging process. view more (2008-04-18)
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