From beaker to bits: Collaboration creates computational model of human tissue
Computer scientists and biologists in the Data Science Research Center at Rensselaer Polytechnic Institute have developed a rare collaboration between the two very different fields to pick apart a fundamental roadblock to progress in modern medicine. View More (2012-04-03)
Drug combination may provide option to patients with NSCLC ineligible for bevacizumab
A combination of nab-paclitaxel and carboplatin for the treatment of non-small cell lung cancer may be a promising option for patients ineligible for treatment with bevacizumab. View More (2012-04-03)
Innovative efforts to reduce colorectal cancer disparities in Alaska Native population
In recognition of National Colorectal Cancer Awareness Month, GIE: Gastrointestinal Endoscopy has published a special issue for March on colorectal cancer. View More (2012-03-07)
Women with certain type of ovarian cancer and BRCA gene mutation have improved survival at 5 years
Among women with invasive epithelial ovarian cancer, patients having a germline (gene change in a reproductive cell that could be passed to offspring) mutation in the BRCA1 or BRCA2 genes was associated with improved 5-year overall survival, with BRCA2 carriers having the best prognosis. View More (2012-01-25)
Combination therapy shows potent tumor growth inhibition in preclinical studies
Combining the investigational agents REGN910 and aflibercept yielded statistically significant improvements in antitumor effects in animal models compared with either agent alone, according to results presented at the AACR-NCI-EORTC International Conference: Molecular Targets and Cancer Therapeutics, held Nov. 12-16, 2011. View More (2011-11-14)
Clues to finding further causes for monogenic diabetes
In most cases of diabetes, various genes and environmental factors are involved. Not in monogenic diabetes, where the causes are mutations in just a single gene. View More (2011-09-22)
New Montana State research sheds light on South Pole dinosaurs
Dog-sized dinosaurs that lived near the South Pole, sometimes in the dark for months at a time, had bone tissue very similar to dinosaurs that lived everywhere on the planet, according to a doctoral candidate at Montana State University. View More (2011-08-05)
Novel analysis by Allen Institute sheds new light on the mechanisms of brain development
Scientists at the Allen Institute for Brain Science have taken an important step in identifying how the brain organizes itself during development. View More (2011-08-02)
High EGFR expression a predictor for improved survival with cetuximab plus chemotherapy
High epidermal growth factor receptor (EGFR) expression was a good predictor of which lung cancer patients would survive longer when cetuximab (Erbitux) was added to first-line chemotherapy, according to research presented at the 14th World Conference on Lung Cancer in Amsterdam, hosted by the International Association for the Study of Lung Cancer (IASLC). View More (2011-07-05)
ASGE initiative examines real-time endoscopic assessment of the histology of diminutive colorectal polyps
In recognition of National Colorectal Cancer Awareness Month during March, GIE: Gastrointestinal Endoscopy has put out a special issue for March on colonoscopy and colorectal cancer. View More (2011-03-09)
'Longevity' protein SIRT1 may ward off precursor to prostate cancer
Researchers from the Kimmel Cancer Center at Jefferson and two other institutions have discovered new evidence that suggests the "longevity" protein SIRT1, known for its life-spanning effects in different species, can inhibit the development of a known precursor to prostate cancer, prostatic intraepithelial neoplasia (PIN). View More (2011-01-14)
100-year-old specimens at California museum help determine when avian pox hit Galapagos
A research team from across the United States and Ecuador has pinpointed 1898 as the year the avipoxvirus, or avian pox, hit the Galapagos Islands and started infecting its birds. View More (2011-01-14)
Fox Chase researchers uncover new risk factors for brain metastases in breast cancer patients
Nearly one-fifth of all metastatic breast cancer patients develop brain metastases and have significantly shorter overall survival than patients who do not have brain involvement. View More (2010-12-10)
Mouse brain seen in sharpest detail ever
The most detailed magnetic resonance images ever obtained of a mammalian brain are now available to researchers in a free, online atlas of an ultra-high-resolution mouse brain, thanks to work at the Duke Center for In Vivo Microscopy. View More (2010-10-26)
Race not root of disparity in lung cancer between whites and blacks
Race itself was not a prognostic factor of overall survival among black patients with lung cancer, according to data from a retrospective study presented at the Third AACR Conference on The Science of Cancer Health Disparities. View More (2010-10-04)
PhD thesis investigates in depth the capacity of 4-HPR to induce death of tumour cells, applying it to acute lymphoblastic leukaemia
Retinoic acid (RA), a natural derivative of vitamin A, is the basis of a number of treatments against cancer. Nevertheless, it has certain disadvantages, such as the possibility of the appearance of retinoic acid syndrome, present in 25 % of cases and which can lead to death. View More (2010-09-08)
BioDonostia evaluates the use of a food-related method for the diagnosis of hepatic steatosis
A multidisciplinary research team from the Instituto Biodonostia made up by digestologists, epidemiologists and researchers of the Experimental Unit evaluates the use of a method so far employed in the food industry to improve the diagnosis of hepatic steatosis. View More (2010-07-21)
ESMO publishes updated guidelines on cancer care
The European Society for Medical Oncology (ESMO) just released an enhanced and revised set of clinical recommendations designed to help oncologists deliver the best quality care to their patients. View More (2010-07-09)
New ISHLT cardiac allograft vasculopathy standardized nomenclature
Cardiac allograft vasculopathy (CAV), the major limitation to long term survival after heart transplantation, occurs when blood vessels in a transplanted heart progressively narrow and lead to dysfunction of the heart muscle or sudden death. View More (2010-06-25)
Neonatal diarrhea
Diarrhea represents a major condition responsible for pediatric mortality worldwide. The onset of neonatal diarrhea may rapidly lead to life threatening dehydration and malnutrition. View More (2010-06-17)
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