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NIH launches 2009 H1N1 influenza vaccine trials in HIV-infected pregnant women
The first clinical trials to test whether the 2009 H1N1 influenza vaccine can safely elicit a protective immune response in pregnant women launched yesterday, and a trial to conduct the same test in HIV-infected children and youth will begin next week. view more (2009-10-12)
AIDS surpasses black death as deadliest disease in history
In terms of illness and death, AIDS is worse than the Black Death of the 14th century. Ninety five per cent of new infections of HIV are in the world's poor countries and heterosexual transmission is responsible for most of these, reports Peter Lamptey, in this week's BMJ. view more (2002-01-23)
HIV and malaria combine to adversely affect pregnant women and their infants
University of Toronto researchers have uncovered the basis by which pregnant women protect themselves against malaria and have also discovered how the HIV virus works to counteract this defence. The research could lead to improved vaccines for pregnant women in malaria-ravished regions. view more (2007-05-30)
Second pathway behind HIV-associated immune system dysfunction identified
Researchers at the Partners AIDS Research Center at Massachusetts General Hospital (PARC-MGH) may have discovered a second molecular "switch" responsible for turning off the immune system's response against HIV. view more (2007-10-01)
Older Age Of Male Partners Makes Young Women More Susceptible To Hiv-1 Infection (p 1896)
Results of a field study in Zimbabwe published in this week`s issue of THE LANCET highlight how cultural aspects of sexual behaviour are closely associated with an increased rate of HIV-1 infection among young women compared with young men. HIV-1 prevalence typically rises more rapidly at young ages in women than in men in sub-Saharan Africa. The... view more... (2002-05-29)
Clinical trial finds microbicide promising as HIV prevention method for women
A clinical trial involving more than 3,000 women in the U.S. and southern Africa demonstrates for the first time the promise of a vaginal microbicide gel for preventing HIV infection in women. view more (2009-03-06)
Research suggests new cellular targets for HIV drug development
Focusing HIV drug development on immune cells called macrophages instead of traditionally targeted T cells could bring us closer to eradicating the disease, according to new research from University of Florida and five other institutions. view more (2009-05-28)
Quality not quantity important for immune response to HIV
When it comes to an immune response against HIV, research funded by the Wellcome Trust in the UK and the National Institutes of Health in the US has found that bigger is not necessarily better, contrary to conventional medical wisdom. view more (2006-12-18)
Human testis harbors HIV-1 in resident immune cells
Researchers have demonstrated HIV replication within resident immune cells of the testis, providing an explanation for the persistence of virus in semen even after effective highly active antiretroviral therapy. view more (2006-11-27)
Landmark study defines benefits of early HIV testing and treatment for infected infants
Testing very young babies for HIV and giving antiretroviral therapy (ART) immediately to those found infected with the virus dramatically prevents illness and death, according to a report in the New England Journal of Medicine. view more (2008-11-20)
Novel vaccine approach offers hope in fight against HIV
A research team may have broken the stubborn impasse that has frustrated the invention of an effective HIV vaccine, by using an approach that bypasses the usual path followed by vaccine developers. view more (2009-05-18)
Circumcision Reduces the Risk of HIV Infection in Heterosexual U.S. Men
A new U.S. study has found that being circumcised significantly reduced the risk of HIV infection in heterosexual African American men known to have been exposed to the virus. view more (2008-12-18)
Hepatitis C at epidemic levels among young injectors in London
Levels of hepatitis C among young injecting drug users across London are reaching epidemic levels report researchers from Imperial College London, the Health Protection Agency and the London School of Hygiene and Tropical Medicine. view more (2004-11-10)
Exhaustion of HIV-specific T cells may be caused by chronic exposure to virus
The "exhaustion" of immune cells that target HIV appears to result from chronic exposure to the virus, specifically exposure to the particular protein segments targeted by the pathogen-killing HIV-specific CD8 T cells. view more (2008-05-06)
Male circumcision for HIV prevention and more
Three clinical trials in Africa found that adult male circumcision reduced the risk of men acquiring HIV infection from heterosexual sex by 51-60%. view more (2007-07-24)
ZAMBIAN WOMEN SUPPORT MASS NEVIRAPINE DISTRIBUTION (p 1611)
Pregnant women in Zambia-a country with high HIV-1 prevalence-would support a mass distribution campaign for the HIV drug nevirapine, according to a survey detailed in a research letter in this week's issue of THE LANCET. view more (2001-11-07)
New study debunks misconceptions about barriers to the CDC's HIV testing recommendations
Since the Centers for Disease Control and Prevention (CDC) released revised recommendations for opt-out HIV testing in 2006, there has been significant debate around the barriers to widespread implementation of the recommendations. view more (2009-02-17)
Pitt researchers find candidates for new HIV drugs
While studying an HIV protein that plays an essential role in AIDS progression, researchers at the University of Pittsburgh School of Medicine have discovered compounds that show promise as novel treatments for the disease. view more (2009-10-14)
Genetic variation increases HIV risk in Africans
A genetic variation which evolved to protect people of African descent against malaria has now been shown to increase their susceptibility to HIV infection by up to 40 per cent, according to new research. Conversely, the same variation also appears to prolong survival of those infected with HIV by approximately two years. view more (2008-07-17)
HIV-1's 'hijacking mechanism' pinpointed by McGill/JGH researchers
Researchers at McGill University and the affiliated Lady Davis Institute for Medical Research at Montreal's Jewish General Hospital - along with colleagues at the University of Manitoba and the University of British Columbia - may have found a chink in the armour of the human immunodeficiency virus type 1 (HIV-1), the microorganism which causes... view more... (2009-06-11)
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