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Protein identified that turns off HIV-fighting T cells
In HIV-infected patients the body's immune system is unable to fight off the virus. A new study to be published online on November 10th in the Journal of Experimental Medicine shows that T cells in HIV-infected individuals express a protein called TIM-3, which inactivates their virus killing capacity. view more (2008-11-10)
Challenges of HIV-1 subtype diversity
A review article in the New England Journal of Medicine explores the genetic variation of HIV-1 and its implications for preventing and treating the disease. Francine McCutchan, Ph.D., a researcher with the U.S. Military HIV Research Program, co-authored the article, which appeared in the April 10, 2008 edition. view more (2008-05-22)
HIV-infected infants respond poorly to childhood vaccination
It is known that HIV-infected children who do not receive appropriate antiretroviral drugs experience immune depression, and may become susceptible to infectious diseases that would otherwise be prevented by childhood immunization. view more (2007-12-05)
HIV-1-Positive Women At Increased Risk Of Genital Cancer
A study in this week's issue of THE LANCET suggests that women who are HIV-1 positive are at an increased risk of invasive genital cancer. Authors of the study recommend that gynaecological examination of these women should include examination of the vulva and perianal region to identify genital warts, which can lead to the development of invasive... view more... (2002-01-11)
Increased HIV risk for women with violent male partners (pp 1410, 1415)
South African research published in this week's issue of THE LANCET highlights how women with physically violent and controlling male partners are at an increased risk of HIV-1 infection. HIV/AIDS is more widespread among women in sub-Saharan Africa than any other population. Although violence from a male partner and relationship inequalities are... view more... (2004-04-28)
HIV positive and HIV negative patients have similar survival rates following liver transplant
HIV positive and HIV negative patients have comparable survival rates following liver transplant, according to new research presented today at EASL 2009, the Annual Meeting of the European Association for the Study of Liver in Copenhagen, Denmark. view more (2009-04-24)
Circumcision for prevention of HIV: new analysis demonstrates cost-effectiveness
A team of researchers who conducted a landmark trial in Orange Farm, South Africa, which concluded that male circumcision can sub stantially reduce the risk of becoming infected with HIV, have now studied the economic aspects of this approach to preventing HIV/AIDS. view more (2006-12-26)
NIAID media availability: New strategy proposed for designing antibody-based HIV vaccine
Most vaccines that protect against viruses generate infection-fighting proteins called antibodies that either block infection or help eliminate the virus before it can cause disease. view more (2009-06-15)
How HIV vaccine might have increased odds of infection
In September 2007, a phase II HIV-1 vaccine trial was abruptly halted when researchers found that the vaccine may have promoted, rather than prevented, HIV infection. view more (2008-11-03)
Antiretroviral Therapy Effective In Reducing Mother-to-child HIV-1 Transmission When Started After Childbirth (p 1171)
Results of a study from Malawi in this week's issue of THE LANCET highlight how antiretroviral therapy targeted at babies soon after childbirth (because their mothers' HIV diagnosis was made around the time of delivery) is still effective in preventing vertical HIV-1 transmission from mothers to their children. Zidovudine and nevirapine have been... view more... (2003-10-08)
A new step towards an AIDS vaccine
Progressive disease after HIV infection is inversely correlated with the presence of plasmacytoid dendritic cells (pDCs), a subset of the dendritic cell family and the major producers of type 1 interferon in the body. view more (2005-10-14)
Well-armed immune cells help long-term nonprogressors contain HIV
To help develop an effective HIV vaccine, researchers are trying to better understand how the immune systems of a small minority of HIV-infected people known as long-term non-progressors (LTNPs) contain the virus naturally. view more (2008-12-05)
Gains in access to antiretroviral treatment come with some costs
In this week's PLoS Medicine magazine, Yibeltal Assefa, from the National HIV/AIDS Prevention and Control Office in Addis Ababa, and colleagues describe the successes and challenges of the scale-up of antiretroviral treatment (ART) across Ethiopia. view more (2009-04-28)
A low prevalence of H pylori in HIV-positive patients
Helicobacter pylori has been extensively studied and proven to be the main cause of chronic gastritis and peptic ulcer in the HIV-negative population. view more (2007-10-17)
Implications of the new HIV estimate for India
The 2007 UNAIDS/WHO AIDS epidemic update released last week has revised the global estimate of HIV/AIDS primarily due to a major reduction of the estimate for India to 2.5 million people living with HIV/AIDS, which is less than half of the previous official estimate of 5.7 million people. view more (2007-12-04)
Why are so few HIV/AIDS trials conducted in Africa?
People in sub-Saharan Africa carry the heaviest burden of HIV and AIDS, yet very few trials have been conducted on the African continent over the past two decades, say researchers in this week's BMJ. view more (2005-09-30)
MicroRNAs help control HIV life cycle
Scientists at Burnham Institute for Medical Research (Burnham) have discovered that specific microRNAs (non-coding RNAs that interfere with gene expression) reduce HIV replication and infectivity in human T-cells. view more (2009-06-26)
HIV patients sicker when seeking care than in the past
It was hoped that as HIV treatment improved and as HIV-related public health initiatives encouraged people to be tested for the disease and seek care, that HIV-infected patients would seek care quickly. view more (2007-10-26)
Immune exhaustion in HIV infection
As HIV disease progresses in a person infected with the HIV virus, a group of cells in the immune system, the CD8+ T lymphocytes, become "exhausted," losing many of their abilities to kill other cells infected by the virus. view more (2008-05-06)
Eastern Europe Facing Major Aids Epidemic (p 1035)
Authors of a review in this week's issue of THE LANCET predict that social problems in former eastern-block countries resulting in large numbers of injecting-drug users and a rise in sexually transmitted diseases will soon cause a major HIV/AIDS epidemic in eastern Europe. Fran'§oise Hamers and Angela Downs describe recent trends in the HIV... view more... (2003-03-20)
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