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Are certain congenital birth defects and heart disease linked?
The study implicates homocysteine, a chemical by-product of human metabolism. Homocysteine is particularly important for cell growth and is regulated by enzymes, the activities of which are partly genetically determined, and partly affected by diet, including the levels of vitamins B6, B12, and... view more (1999-11-15)

Folic acid could prevent heart disease
Folic acid could dramatically reduce the risk of heart disease, deep vein thrombosis, and stroke if levels of homocysteine (an amino acid) were reduced, according to researchers in this week’s BMJ.   view more (2002-11-20)

Folic Acid Can Prevent Heart Disease
Folic acid is not only a safeguard against spina bifida and other birth defects in babies - it can also prevent heart disease and strokes, two of Northern Ireland's biggest killers, according to research from the University of Ulster. Research at the University has shown and folic acid and three... view more (2002-09-18)

Food Fortification With Vitamin B12 In Addition To Folic Acid Could Reduce Risk Of Cardiovascular Disease (p 227)
Authors of a research letter in this week's issue of THE LANCET conclude that vitamin B12 in addition to folic acid should be used to fortify food to lower concentrations of the blood protein homocysteine, thereby potentially reducing the risk of cardiovascular disease. Mandatory fortification of... view more (2002-01-17)

Not enough 'good' cholesterol makes it harder to recover from stroke
People are at an increased risk of memory problems and greater disability after stroke if they have low levels of "good" cholesterol and high levels of homocysteine, an amino acid acquired mostly from eating meat.   view more (2007-11-27)

Higher folate levels linked to reduced risk for Alzheimer's disease
Individuals who take in higher levels of the nutrient folate through both diet and supplements may have a reduced risk of developing Alzheimer's disease.   view more (2007-01-09)

Impact of elevated homocysteine levels on vision under study
Homocysteine, an amino acid believed to contribute to heart attack, stroke and dementia, likely also is a player in retinal damage and vision loss, researchers say.   view more (2007-10-16)

Predicting the risk of death in patients with known coronary artery disease
The extent of anatomic coronary artery disease, along with age and the presence of diabetes, is a strong predictor of subsequent death due to any cause and due to coronary artery disease (CAD).   view more (2006-02-14)

Biomarker for age-related macular degeneration found
People who have elevated homocysteine in their blood, an amino acid that is a known biomarker for cardiovascular disease, may also be at an increased risk of developing age-related macular degeneration (AMD), according to a study in the January issue of the American Journal of Ophthalmology.   view more (2006-01-05)

U of I scientist develops enzyme inhibitor that may slow cancer growth
University of Illinois scientist Tim Garrow, in collaboration with Jiri Jiracek of the Czech Academy of Sciences, has applied for a provisional patent on a class of chemicals that has future therapeutic uses in medicine, specifically cancer treatment.   view more (2006-07-07)

Study finds B-vitamin deficiency may cause vascular cognitive impairment
A deficiency of B-vitamins may cause vascular cognitive impairment, according to a new study. Researchers at the Jean Mayer USDA Human Nutrition Research Center on Aging (HNRCA) at Tufts University used an experimental model to examine the metabolic, cognitive, and microvascular effects of dietary... view more (2008-09-02)

Vitamin B does not slow cognitive decline in Alzheimer's
A clinical trial led by Paul S. Aisen, M.D., professor of neurosciences at the University of California, San Diego School of Medicine, showed that high-dose vitamin B supplements did not slow the rate of cognitive decline in patients with mild to moderate Alzheimer disease.   view more (2008-10-15)

Indicators for risk of heart disease are higher in passive smokers
Exposure to second-hand smoke at work, home or elsewhere results in a disproportionate rise in markers that increase the risk of cardiovascular disease, University of Nottingham researchers have found.   view more (2007-02-13)

Compound that helps rice grow reduces nerve, vascular damage from diabetes
You may want to soak your brown rice. Researchers have found that a compound that helps rice seed grow, springs back into action when brown rice is placed in water overnight before cooking, significantly reducing the nerve and vascular damage that often result from diabetes.   view more (2008-07-29)

Low folate levels may cut bowel cancer risk
Low levels of folate, a B vitamin found in fruits and leafy green vegetables, may cut the risk of bowel cancer, suggests research published ahead of print in the journal Gut.   view more (2006-04-25)

ESC Congress 2003: Prothrombotic mutations are associated with increased cardiovascular events in postmenopausal women receiving hormone replacement therapy
IMPORTANT: This press release accompanies a poster or oral session given at the ESC Congress 2003. Written by the investigator himself/herself, this press release does not necessarily reflect the opinion of the European Society of Cardiology Recent studies have suggested that hormone replacement... view more (2003-09-01)

Vitamin B12 function may be diminished by excessive folate
In a study of adults aged 20 and over, researchers at Tufts University showed that homocysteine and methylmalonic acid are at much higher levels in individuals who have a combination of vitamin B12 deficiency and high blood folate levels than in individuals who are also vitamin B12 deficient but... view more (2007-12-19)

With Your Diet You Can Prevent Depression
Two studies published in the 2004 November- December issue of Psychotherapy and Psychosomatics suggest that dietary B vitamin complex has an important role as to the vulnerability to depression. In the first study, a group of Finnish investigators of the University of Kuopio found that a low... view more (2004-11-18)

ESC Spokespersons assess the viability of the 'Polypill' for cardiovascular disease prevention
ESC Spokespersons speak out on the concept of the 'Polypill', proposed by British scientists as a daily formula of six medications, to be taken by heart patients and all those over 55 years old, to avert more than 80 percent of heart attacks and strokes. The 'Polypill', proposed by Dr Nicolas Wald... view more (2003-06-27)

Study identifies trends of vitamin B6 status in US population sample
In an epidemiological study, Tufts University researchers identified trends of vitamin B6 status in a sample of the United States population based on measures of plasma pyridoxal 5'- phosphate (PLP) levels in the bloodstream. Plasma PLP is the indicator used by the federal government to set the... view more (2008-05-21)

Higher level of certain fatty acid associated with lower dementia risk
Individuals who have higher levels of a fatty acid known as docosahexaenoic acid (DHA) in their blood may have a significantly lower risk of developing dementia and Alzheimer's disease.   view more (2006-11-14)

Dutch diet contains too little folic acid
The average Dutch person consumes about 85% of the recommended daily intake of folic acid. Furthermore, it is estimated that our bodies fail to absorb no less than one quarter of the folic acid in food. These findings were made by Alida Melse-Boonstra during her doctoral research, which she carried... view more (2003-09-05)

Researchers discover gene behind devastating vitamin B12-related disorder
Swiss, British and Canadian researchers have identified the gene responsible for a rare but serious genetic disorder and have simultaneously provided more clues as to how vitamin B12 works in the body. Their results will be published April 3 in the New England Journal of Medicine.   view more (2008-04-03)

SNPs affect folate metabolism in study of Puerto-Rican adults
Researchers at Tufts University have gained further understanding of the genomic basis for altered folate metabolism and the content of uracil in blood DNA.   view more (2008-11-11)

MUHC and McGill scientists identify gene for debilitating vitamin B12 disease
Scientists at the MUHC and McGill University have identified a gene responsible for a disease that impairs the body's ability to handle vitamin B12 and that may contribute to heart disease, stroke and dementia.   view more (2005-12-01)
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