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Study indicates grape seed extract may reduce cognitive decline associated with Alzheimer's disease
A compound found in grape seed extract reduces plaque formation and resulting cognitive impairment in an animal model of Alzheimer's disease, new research shows. The study appears in the June 18 issue of The Journal of Neuroscience. view more (2008-06-18)
Alzheimer's vaccine clears plaque but has little effect on learning and memory impairment
A promising vaccine being tested for Alzheimer's disease does what it is designed to do - clear beta-amyloid plaques from the brain - but it does not seem to help restore lost learning and memory abilities, according to a University of California, Irvine study. view more (2008-04-07)
Ben-Gurion University Alzheimer's researcher demonstrates specific immune response to vaccine
A researcher who is working on a vaccine for Alzheimer's disease (AD) has demonstrated that it is possible to test and measure specific immune responses in mice carrying human genes and to anticipate the immune response in Alzheimer's patients. view more (2009-09-21)
Enzyme action creates protein linked to Alzheimer's disease
Researchers at UT Southwestern Medical Center have defined a key step in the production of beta-amyloid, a short protein that is thought to be responsible for the development of Alzheimer's disease. view more (2005-08-15)
Understanding Heart Disease: Research Explains Link Between Cholesterol and Heart Disease
Cholesterol contributes to atherosclerosis - a condition that greatly increases the risk of heart attack and stroke - by suppressing the activity of a key protein that protects the heart and blood vessels, researchers at the Saint Louis University School of Medicine have found. view more (2007-09-19)
Gastric cancer with 3 pathological features
Primary carcinoma of the stomach is almost always adenocarcinoma or signet ring cell carcinoma and there are few reports of choriocarcinoma or neuroendocrine cell carcinoma. view more (2008-09-18)
Compound in wine reduces levels of Alzheimer's disease-causing peptides
A study published in the November 11 issue of the Journal of Biological Chemistry shows that resveratrol, a compound found in grapes and red wine, lowers the levels of the amyloid-beta peptides which cause the telltale senile plaques of Alzheimer's disease. view more (2005-11-04)
Looking beyond the drug receptor for clues to drug effectiveness
Antipsychotic drugs that are widely used to treat schizophrenia and other problems may not work as scientists have assumed, according to findings from Duke University Medical Center researchers that could lead to changes in how these drugs are developed and prescribed. view more (2008-08-26)
Counselling can increase fruit and vegetable intake
Behavioural counselling can increase consumption of fruit and vegetables among deprived adults, finds a study in this week's BMJ. Researchers identified 271 patients, aged 18-70 years, from a health centre in a deprived, ethnically mixed inner city area. Patients were randomly assigned to two groups. One group received behavioural counselling... view more... (2003-04-15)
Zeroing in on Alzheimer's
Hereditary Alzheimer's disease has been shown to be the result of mutations in certain specific genes. Other cases of Alzheimer's are also assumed to be traceable to the influence of a number of still unidentified genes. It is probable that these genes are located in a large area on chromosome 10q, which contains more than 100 genes. Working with... view more... (2003-09-25)
Key protein that may cause cancer cell death identified
Researchers at A*STAR's Institute of Molecular and Cell Biology (IMCB) have become the first to discover and characterize a human protein called Bax-beta (Baxβ), which can potentially cause the death of cancer cells and lead to new approaches in cancer treatment. view more (2009-01-20)
The anti-diabetic effects of sodium tungstate revealed
The molecular mechanisms of tungstate activity in diabetes have been uncovered. Researchers writing in the open access journal BMC Genomics have identified the pathways through which sodium tungstate improves pancreatic function and beta cell proliferation. view more (2009-08-28)
'Polypill' improves survival rates for heart disease sufferers, says University study
A 'polypill' made up of a combination of drugs could extend the lives of thousands of patients with coronary heart disease, say researchers at The University of Nottingham. view more (2005-05-09)
Green tea ingredient prevents Alzheimer's-like brain damage in mice
Researchers at the University of South (USF) have found that green tea may offer another potential health benefit - protecting the brain against the ravages of Alzheimer's disease. view more (2005-09-21)
Researchers reverse juvenile diabetes in animal model; Clinical trial FDA approved
Groundbreaking human clinical trial for type 1 diabetes to start this spring in Pittsburgh - Children's Hospital of Pittsburgh of UPMC researchers reverse juvenile diabetes in animal model; Phase 1 clinical trial approved by FDA. view more (2006-03-28)
Could skin cells become brain cells? (p 172)
Results of an experimental study in this week's issue of THE LANCET highlight how adult skin cells can be made into precursor nerve cells, with potential implications for the future treatment of neurodegenerative disorders such as Parkinson's disease. Ethical and practical considerations limit the availability of neural stem cells derived from... view more... (2004-07-07)
New study of human pancreases links virus to cause of type 1 diabetes
A team of researchers from the Peninsula Medical School in the South West of England, the University of Brighton and the Department of Pathology at Glasgow Royal Infirmary, has found that a common family of viruses (enteroviruses) may play an important role in triggering the development of diabetes, particularly in children. view more (2009-03-06)
Potential Alzheimer's disease drug target identified by UC San Diego researcher
In findings with the potential to provide a therapy for Alzheimer's disease patients where none now exist, a researcher at the University of California, San Diego and colleagues have demonstrated in mice a way to reduce the overproduction of a peptide associated with the disease. view more (2008-03-17)
Mutation in tumor suppressor gene causes pancreatic islet cells to reproduce
Researchers at the University of Pennsylvania School of Medicine have found that the acute loss of a protein called menin can cause the proliferation of pancreatic islet cells, which secrete insulin to regulate blood sugar. view more (2006-07-06)
Common beta-agonist inhalers more than double death rate in COPD patients, Cornell and Stanford scientists assert
A new analysis that compares two common inhalers for patients suffering from chronic obstructive pulmonary disease (COPD) finds that one reduces respiratory-related hospitalizations and respiratory deaths, but the other — which is prescribed in the majority of cases — increases respiratory deaths. view more (2006-07-10)
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