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Researchers close in on origins of main ingredient of Alzheimer's plaques
The ability of brain cells to take in substances from their surface is essential to the production of a key ingredient in Alzheimer's brain plaques, neuroscientists at Washington University School of Medicine in St. Louis have learned. view more (2008-04-10)
Detection Of Antibodies Could Identify MS Patients Who Do Not Respond Well To Interferon Beta (P1184)
Danish research published in this week's issue of THE LANCET highlights how the detection of antibodies to interferon beta-the first choice treatment for multiple sclerosis patients-could be important in identifying patients who do not respond well to interferon beta, with implications for the provision of alternative drug therapy. Interferon beta... view more... (2003-10-08)
Joslin researchers uncover potential role of leptin in diabetes
A new Joslin-led study has shown that leptin, a hormone known mainly for regulating appetite control and energy metabolism, plays a major role in islet cell growth and insulin secretion. view more (2007-10-02)
Enzyme may be a key to Alzheimer's-related cell death
A Purdue University researcher has discovered that the amount of an enzyme present in neurons can affect the mechanism thought to cause cell death in Alzheimer's disease patients and may have applications for other diseases such as stroke and heart attack. view more (2009-10-08)
Moderate use averts failure of type 2 diabetes drugs in animal model
Drugs widely used to treat type 2 diabetes may be more likely to keep working if they are used in moderation, researchers at Washington University School of Medicine in St. Louis have found in a study using an animal model. view more (2008-10-28)
Noninsulin-producing alpha cells in the pancreas can be converted to insulin-producing beta cells
In findings that add to the prospects of regenerating insulin-producing cells in people with type 1 diabetes, researchers in Europe -- co-funded by the Juvenile Diabetes Research Foundation -- have shown that insulin-producing beta cells can be derived from non-insulin-producing cells in the pancreas. view more (2009-08-07)
Joslin-led study reveals findings on how insulin-producing beta cells grow and function
Joslin-led study reveals findings on how insulin-producing beta cells grow and function view more (2006-04-24)
The stem cells that weren't there
Diabetes researchers, investigating how the body supplies itself with insulin, discovered to their surprise that adult stem cells, which they expected to play a crucial role in the process, were nowhere to be found. view more (2007-05-08)
Can tomatoes carry the cure for Alzheimer's?
The humble tomato could be a suitable carrier for an oral vaccine against Alzheimer's disease, according to HyunSoon Kim from the Korea Research Institute of Bioscience and Biotechnology (KRIBB) in Korea and colleagues from Digital Biotech Inc. and the Department of Biological Science at Wonkwang University. Although their research1, just... view more... (2008-07-09)
Anaemia Treatment Could Worsen Cancer Prognosis (p1255)
Results of a European study in this week's issue of THE LANCET cast doubt over the value of treating anaemia with erythropoietin (epoetin beta) among patients who have cancer. Results of the study show that anaemic patients fare better in terms of reduced cancer progression and increased survival if their anaemia is not treated around the time of... view more... (2003-10-15)
Heart regenerates after infarction -- first trials with mice
Up until today scientists assumed that the adult heart is unable to regenerate. Now, researchers and cardiologists from the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch and the Charité - Universitätsmedizin Berlin (Germany) have been able to show that this dogma no longer holds true. view more (2008-12-12)
Teamwork between 2 key proteins necessary for normal development and regulation of red blood cells
Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells. view more (2007-08-07)
NIAID scientists identify new cellular receptor for HIV
A cellular protein that helps guide immune cells to the gut has been newly identified as a target of HIV when the virus begins its assault on the body's immune system, according to researchers from the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH). view more (2008-02-11)
Increased sensitivity to nerve signals keeps diabetes at bay
Nerve signals relayed directly to the pancreas after eating a meal play a critical role in normal blood sugar control. view more (2006-06-07)
Yeast model shows promise as Alzheimer's test
A century ago this month, German psychiatrist Alois Alzheimer formally described characteristics of the neurodegenerative disease which ultimately came to bear his name. view more (2006-11-20)
Gladstone researchers identify new drug target for Alzheimer's disease
Researchers at the Gladstone Institute of Neurological Disease have identified a potential new way to stop brain cell death related to Alzheimer's disease. view more (2005-12-02)
How to grow muscle cells in a dish
Smooth muscle cells (SMCs) are a crucial cellular component of many parts of the body, including blood vessels, the intestines, and the lungs. view more (2006-11-10)
BUDGET FOR INTERFERON BETA FOR MS SUFFERERS WOULD BE BETTER SPENT ON IMPROVED SUPPORTIVE CARE
Dr Raeburn Forbes from Ninewells Hospital and Medical School in Dundee along with colleagues from Argyll and Clyde Health Board and the Scottish Health Purchasing Information Centre studied 132 people with secondary progressive multiple sclerosis and the estimated effect of treating them with interferon beta-1b against existing best practice... view more... (1999-12-08)
Team reveals molecular mechanism underlying a form of diabetes
By investigating a rare and severe form of diabetes in children, University of Iowa researchers have discovered a new molecular mechanism that regulates specialized pancreatic cells and insulin secretion. view more (2009-09-09)
Birth defect gene identified
Birth defects of the face and skull are relatively common in humans, striking one in 500 to 1,000 babies. Defects can include cleft lip or palate, congenitally missing teeth and severe malformations of the skull. view more (2005-12-23)
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