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Hypoxic Response Current Events | Hypoxic Response News

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Researchers link master regulator of innate immunity to the hypoxic response
Survival of all animals depends on their ability to withstand microbial infections and adapt to fluctuations in oxygen concentrations.   view more (2008-04-24)

FOXO factor promotes survival of oxygen-deprived cancer cells
Scientists report that an evolutionarily conserved transcription factor may have both positive and negative effects on the growth of tumors, depending on whether or not the tumor cells have enough oxygen.   view more (2007-12-28)

University of Kent bioscientists receive grant to research novel cancer treatment
Dr Phil Blower and Dr Dan Lloyd from the Department of Biosciences at the University of Kent - together with Dr Paul Marsden at the St Thomas' Hospital Clinical PET Centre in London - have been awarded £347,906 from the Engineering and Physical Sciences Research Council and the Medical... view more (2004-03-16)

Stanford scientists identify protein involved in fast-spreading cancers
Researchers at the Stanford University School of Medicine have found a protein that may explain why tumors in a low-oxygen environment are more deadly.   view more (2006-04-27)

New therapy shows promise for fighting treatment-resistant cancer cells
A gene radiotherapy system that detects and treats cancer cells that are resistant to traditional forms of chemotherapy and radiation showed success in the laboratory and could eventually prove beneficial for cancer patients, according to researchers at SNM's 55th Annual Meeting.   view more (2008-06-17)

Adaptation to oxygen deprivation elucidates tumor physiology
Two new studies in the March Cell Metabolism reveal a survival mechanism by which cells adapt to oxygen starvation by ratcheting down their demand.   view more (2006-03-08)

Second low-oxygen pathway hints at cancer, cardiovascular disease physiology
Researchers at the University of Pennsylvania School of Medicine have identified a second molecular pathway that promotes cell survival in low-oxygen conditions.   view more (2006-02-17)

New tool tracks brain development in babies
Researchers have used a new technique to monitor brain development in infants and detect disturbances in white matter, according to a study in the July issue of Radiology.   view more (2006-06-27)

Deadly hypoxic event finally concludes
The longest, largest and most devastating hypoxic event ever observed in marine waters off the Oregon Coast has finally ended.   view more (2006-10-31)

Ways to avoid hazards of heart bypass under study
The heart-lung bypass machine that stills the heart while surgeons bypass an adult's clogged arteries or repair a baby's malformed heart can also trigger a potentially deadly inflammatory response.   view more (2005-08-29)

Adaptive functional evolution of leptin in cold-adaptive pika family
Researchers at the Northwest Institute of Plateau Biology, Chinese Academy of Sciences have put forward the viewpoint for the first time that adaptive functional evolution may occur in the leptin protein of the pika (Ochotona) family, a typical cold-adaptive mammal.   view more (2008-01-23)

Scientists unlock solid tumor treatment genetic secrets
A biochemical mechanism that cells use to cope with hypoxia (lack of oxygen) actually cooperates with a less well-known mechanism that helps increase the expression of those hypoxia-sensitive genes.   view more (2005-12-02)

Low oxygen in coastal waters impairs fish reproduction
Low oxygen levels in coastal waters interfere with fish reproduction by disrupting the fishes' hormones, a marine scientist from The University of Texas at Austin Marine Science Institute has found.   view more (2007-08-29)

Pomegranate juice for moms may help babies resist brain injury
Expectant mothers at risk of premature birth may want to consider drinking pomegranate juice to help their babies resist brain injuries from low oxygen and reduced blood flow, a new mouse study from Washington University School of Medicine in St. Louis suggests.   view more (2005-06-28)

Shorter ambulance response times would cut heart attack deaths
Reducing ambulance response times to 5 minutes could almost double the survival rate for cardiac arrests not witnessed by ambulance crews, finds a study in this week's BMJ. All out of hospital cardiopulmonary arrests due to cardiac disease attended by the Scottish Ambulance Service during May 1991... view more (2001-06-06)

Resuscitation technique after brain injury may do more harm than good
The current standard practice of giving infants and children 100 percent oxygen to prevent brain damage caused by oxygen deprivation may actually inflict additional harm, researchers at UT Southwestern Medical Center have found.   view more (2008-07-01)

Smoking during pregnancy increases risk of SIDS
A new study provides the most direct evidence that there exists a causal link between smoking during pregnancy and Sudden Infant Death Syndrome (SIDS).   view more (2008-05-30)

A new chemotherapeutic target for hepatocellular carcinoma
Hepatocellular carcinoma (HCC) is a major health problem worldwide. Currently, the only chance for obtaining a cure in patients with HCC is by either a surgical resection or liver transplantation.   view more (2007-10-25)

The old, cheap antidepressant drugs may be more effective than the newer ones
Carlo Faravelli and collegues at the University of Florence published a study in Psychotherapy and Psychosomatics thet the Big Pharma would have never funded. 114 of 2,000 outpatients drawn from a private facility with a diagnosis of mood or anxiety disorder had two separate episodes during which... view more (2003-03-11)

Ocean 'dead zones' trigger sex changes in fish, posing extinction threat
Oxygen depletion in the world's oceans, primarily caused by agricultural run-off and pollution, could spark the development of far more male fish than female, thereby threatening some species with extinction.   view more (2006-03-30)

DVT Risk From Air Travel Unrelated To Reduced Air Pressure In Cabin (p 2207)
Results of a study published as a research letter in this week's issue of THE LANCET suggest that reduced air pressure (leading to decreased oxygen availability) in pressurised aircraft cabins is not associated with increased activity of the agents responsible for blood clotting and potential... view more (2003-06-25)

Thale cress goes on the defensive
Thale cress has a complicated defence technique against insects and microorganisms that use the plant as a source of food.   view more (2007-05-15)

Inhaled nitric oxide may help sickle cell disease
Inhaling a small dose of nitric oxide gas may one day help sickle cell patients avoid pain crises and live healthier lives, researchers say.   view more (2005-10-24)

Monitoring the response to vaccination against melanoma
A new study published in PLoS Medicine this week describes a way to measure the immune response in people treated with an experimental vaccine to melanoma.   view more (2005-09-20)

IL-21 receptor plays an essential role in the Th2 immune response
During the immune response cells known as Th2 cells express a variety of cytokines (e.g. interleukin-4, -5, and -13), many of which stimulate B cells to proliferate and produce antibodies.   view more (2006-06-16)
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