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Idiopathic Pulmonary Fibrosis Current Events | Idiopathic Pulmonary Fibrosis News | 5

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Ibuprofen can slow lung disease in children with cystic fibrosis, Canadian study shows
The results of a clinical trial, published in late August in the Journal of Pediatrics, indicates that, when used as part of routine therapy, high-dose ibuprofen is safe, and effective in slowing down lung disease in children with cystic fibrosis (CF).   view more (2007-09-05)

Sildenafil prevents rebound pulmonary hypertension in infants
A single dose of sildenafil, a blood vessel widening vasodilator, prevented rebound pulmonary hypertension and significantly reduced the duration of mechanical ventilation in intensive care unit (ICU) infants being withdrawn from inhaled nitric oxide therapy.   view more (2006-11-01)

Blood clots in lungs might not always originate in deep veins of legs and pelvis in trauma patients
Few trauma patients who develop potentially deadly blood clots in the lungs (pulmonary embolism) also have clots in the deep veins of their pelvis and legs (deep venous thrombosis), challenging commonly held beliefs about the association between the two conditions.   view more (2009-10-20)

Study suggests some breast cancer patients facing radiation after a mastectomy may be over-treated
A new study suggests standard radiation therapy for some breast cancer patients may not be medically required and may, therefore, be causing unnecessary serious side effects such as lymphedema and pulmonary problems.   view more (2008-09-22)

Research provides promising evidence of new drug therapies in lethal lung disease
Several promising new treatments may prolong lives as well as improve the quality of life for people living with pulmonary arterial hypertension.   view more (2006-04-07)

MRI predicts liver fibrosis, study says
Moderate to severe chronic liver disease can be predicted with the use of diffusion-weighted MRI (DWI), according to a recent study conducted by researchers at New York University Medical Center in New York, NY.   view more (2007-10-24)

Study helps explain origins of cardiac fibrosis in patients with heart disease
A report led by researchers at Beth Israel Deaconess Medical Center (BIDMC) helps explain the origins of cardiac fibrosis, a stiffening of the heart muscle that leads to a variety of cardiac diseases, most notably heart failure.   view more (2007-07-30)

U of M study shows why treatment isn't effective for HIV
University of Minnesota researchers have answered a key question as to why antiretroviral therapy isn't effective in restoring immunity in HIV-infected patients.   view more (2008-08-06)

High rate of complicated idiopathic gallstone disease in pediatric patients
The prevalence of gallstones in adults of industrialized countries is approximately 10% and is showing a tendency to rise. Data for pediatric patients is scarce.   view more (2008-04-30)

A simple, noninvasive test measures survival time in adult pulmonary hypertension
Researchers have developed a simple, noninvasive way to measure right ventricular function in the heart to predict survival of adults who suffer from pulmonary hypertension.   view more (2006-11-01)

New Respiratory Research Will Help Patients Breathe Easier
A senior lecturer at Kingston University is embarking on a new research programme that could improve the quality of life for thousands of respiratory disease sufferers. Dr Rachel Garrod is investigating the impact of pulmonary rehabilitation on patients with Chronic Obstructive Pulmonary Disease (COPD). COPD causes an obstruction of the airways... view more... (2003-11-24)

Are bone marrow mononuclear cells effective in reducing hepatic lesions?
Liver fibrosis occurs in the setting of chronic injury caused by different etiologies constituting a serious worldwide public health problem. In addition to schistosomiasis, hepatopathies due to alcohol, viral hepatitis, drugs, metabolic and autoimmune diseases, and congenital abnormalities are important causes of liver fibrosis.   view more (2008-10-24)

Scientists identify novel way to prevent cardiac fibrosis
In a study that points to a new strategy for preventing or possibly reversing fibrosis - the scarring that can lead to organ and tissue damage - researchers at the University of California, San Diego School of Medicine have determined that a molecule called Epac (Exchange protein activated by cAMP1), plays a key role in integrating the body's pro-... view more... (2008-04-23)

Tracking Cystic Fibrosis with Mice: DFG fellow develops an animal model for the disease
Cystic fibrosis, also known as mucoviscidosis, is one of the most common genetic diseases with a fatal outcome in western Europe. The disease is caused by a defective gene that affects the salt and fluid composition of respiratory tract secretions. As a result, they become highly viscous. The viscous mucous then clumps in the smaller lung... view more... (2004-04-26)

Clues to gene expression in cystic fibrosis will guide research
Genetics tests could help provide cystic fibrosis (CF) patients with targeted treatment in future, pilot study authors suggest. Results from a French clinical trial published today in BMC Medicine show how a small percentage of CF sufferers with a rare genetic stop mutation responded positively to gentamicin treatment.   view more (2007-03-29)

U-M researchers find those with severe H1N1 at risk for pulmonary emboli
University of Michigan researchers have found that patients with severe cases of the H1N1 virus are at risk for developing severe complications, including pulmonary emboli, according to a study published today in the American Journal of Roentgenology.   view more (2009-10-15)

Who is the arch-criminal in the development of hepatopulmonary syndrome?
The hepatopulmonary syndrome (HPS) develops when an arterial oxygenation deficiency occurs due to intra-pulmonary vascular dilatations that are often associated with severe hepatic disease. HPS occurs in 15-20% of patients with liver cirrhosis undergoing evaluation for orthotopic liver transplantation.   view more (2007-12-20)

Gene may inhibit smokers from quitting
Smokers with a particular genetic make-up (genotype) may find it harder to give up their habit, suggest Japanese researchers in Thorax. The presence of a CYP2A6del allele, a specific form of the gene involved in processing nicotine in the body, may inhibit smokers from quitting, but it also seems to protect against the development of pulmonary... view more... (2003-06-27)

Putting a stop to antibiotic resistance with new drugs from seaweed
Scientists have found a new way to prevent life-threatening infections not by killing the bacteria but by preventing them from talking to each other, according to research published today in the journal Microbiology. We`ve found that a group of chemicals called furanones can prevent the build up of communities of bacteria on surfaces such as... view more... (2001-12-21)

Researchers identify molecule that causes destructive lung inflammation in cystic fibrosis patients
Scientists at Children's Hospital of Pittsburgh of UPMC have identified a protein that is critical to the development of inflammation during lung infection in patients with cystic fibrosis (CF).   view more (2006-11-07)
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