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Idiopathic Pulmonary Fibrosis Current Events | Idiopathic Pulmonary Fibrosis News | 6

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New approach to treating cystic fibrosis lung infection shows promise
Researchers at the University of Calgary have found a new method of fighting severe lung infections in people with cystic fibrosis (CF). These findings are published in Proceedings of the National Academy of Science USA, this week.    view more (2008-09-23)

Study finds nontuberculous mycobacteria lung disease on the rise in the United States
Nontuberculous mycobacteria (NTM) are environmental organisms found in both water and soil that can cause severe pulmonary (lung) disease in humans. Pulmonary NTM is on the rise in the United States, according to a large study of people hospitalized with the condition.   view more (2009-09-25)

UC San Diego researchers reverse pulmonary arterial hypertension in mouse models
Researchers at the University of California, San Diego, have identified a key protein that promotes the development of pulmonary arterial hypertension in humans and mice.   view more (2009-10-26)

Computer simulations point to key molecular basis of cystic fibrosis
Researchers from the University of North Carolina at Chapel Hill have identified a key molecular mechanism that may account for the development of cystic fibrosis, which about 1 in 3000 children are born with in the US every year.   view more (2008-03-03)

Fistula-related morbidity decreased by prompt treatment in Sierra Leone
Extent of fibrosis is the most profound factor in predicting surgical outcomes of genitourinary fistula repair, suggesting that prompt treatment could significantly improve survival.   view more (2009-04-27)

Noninvasive tests for cirrhosis may help to avoid liver biopsy
Newer ultrasound and magnetic resonance (MR) imaging tests yield encouraging initial results in diagnosing fibrosis (scarring) and cirrhosis of the liver, according to three studies in the October issue of the journal Clinical Gastroenterology and Hepatology.   view more (2007-10-02)

Radiologists encouraged to look beyond cancer for clinically unseen diseases
Radiologists can diagnose venous thromboembolic disease (VTED) in cancer patients earlier by looking more carefully at CT scans of the thorax, abdomen, and pelvis which are regularly done to determine the extent or stage of the cancer.   view more (2007-08-15)

Common cold virus efficiently delivers corrected gene to cystic fibrosis cells
Scientists have worked for 20 years to perfect gene therapy for the treatment of cystic fibrosis, which causes the body to produce dehydrated, thicker-than-normal mucus that clogs the lungs and leads to life threatening infections.   view more (2009-07-21)

Even at High Doses, Gadolinium-Based Contrast Agents Cannot by Themselves Cause Patients to Develop Nephrogenic Systemic Fibrosis
Even at very high doses, gadolinium-based contrast agents alone are not sufficient to cause nephrogenic systemic fibrosis (NSF) in patients with kidney problems.   view more (2009-07-01)

Helping Cystic Fibrosis Patients Beat Bugs
People with weakened immune systems, including patients with cystic fibrosis, could be better protected in future from a highly resilient bacteria thanks to work by medical scientists from the University of Leeds. The research is presented today, Wednesday 10 September 2003, at the Society for General Microbiology's meeting at UMIST in Manchester.... view more... (2003-08-27)

Test predicts risk of liver scarring after transplant, study shows
An estimated 20 percent of people with chronic hepatitis C who receive a liver transplant will develop advanced cirrhosis, scarring of the new organ severe enough to impair its ability to function normally within five years of transplantation.   view more (2005-10-06)

Probe position may change results in liver stiffness measurements in transient elastography
A major clinical challenge is to find the best method to evaluate and to manage the increasing numbers of patients with chronic liver disease. Liver biopsy, due to its risks and limitations, is no longer considered mandatory as the first-line indicator of liver injury, and several markers have been developed as non-invasive alternatives.   view more (2009-07-29)

A potential therapeutic agent for hepatic fibrosis
Accumulating evidence suggests that connective tissue growth factor (CCN2) plays a central role in fibrotic conditions in many organ systems.   view more (2009-08-26)

Tobacco Smoke and Alcohol Harm Liver Worse as Combo
Exposure to second-hand smoke and alcohol significantly raises the risk of liver disease, according to researchers at the University of Alabama at Birmingham (UAB).   view more (2009-02-04)

CU-Boulder technology used to identify unexpected bacteria in cystic fibrosis patients
Molecular technology developed by a University of Colorado at Boulder professor to probe extreme life forms in undersea hydrothermal vents has been used to identify unexpected bacteria strains in the lung fluid of Denver children suffering from cystic fibrosis, findings that may lead to more effective therapies.   view more (2007-12-04)

Little Evidence Behind Bronchodilator Therapy for Cystic Fibrosis
Little evidence exists to support the widespread use of bronchodilators to treat children and adults with cystic fibrosis, according to a new systematic review of published research.   view more (2005-10-26)

Newborns with respiratory distress potentially have rare genetic disease
Newborns with respiratory distress should be evaluated for primary ciliary dyskinesia, a rare genetic disease that has features similar to cystic fibrosis, says Thomas Ferkol, M.D., from Washington University School of Medicine in St. Louis.   view more (2007-02-21)

High blood pressure causes pathological scars in the heart
Fibrosis (scar tissue formation) is the determinant lesion in the subsequent evolution of the heart in a patient with high blood pressure. This item appeared in the latest edition of Nature Clinical Practice Cardiovascular Medicine, a journal that is part of the Nature group. The article published heart research recently carried out at the... view more... (2005-05-25)

NITRIC OXIDE BENEFIT FOR INFANTS UNDERGOING CONGENITAL HEART SURGERY (p 1464)
The cardiovascular problems associated with surgery for congenital heart disease in infants may be reduced with the use of postoperative nitric oxide, according to research published in this week's issue of THE LANCET. Congenital heart disease is present in five to ten per 1000 livebirths. If surgery is required, the most common defects are... view more... (2000-10-25)

Clearing the airways in cystic fibrosis
By manipulating the machinery used by our cells for quality control, researchers from the University of Pittsburgh have found a way to restore the function of cystic fibrosis (CF) airway cells.   view more (2008-08-29)
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