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Idiopathic Pulmonary Fibrosis Current Events | Idiopathic Pulmonary Fibrosis News | 7

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Mayo Clinic Cancer Center finds possible genetic link to pancreatic cancer
Mayo Clinic researchers have found the risk of developing pancreatic cancer at a young age (under 60) to be twice as high for people who carry a mutation of the gene that causes cystic fibrosis, compared to noncarriers.   view more (2005-10-21)

Drug Fights Cystic Fibrosis
An experimental drug that has proven effective in treating muscular dystrophy also works for cystic fibrosis, according to researchers at the University of Alabama at Birmingham (UAB).   view more (2008-02-06)

Strategy Discovered for Fighting Persistent Bacterial Infections
Researchers at National Jewish Health have discovered a promising strategy for destroying the molecular scaffolding that can make Pseudomonas bacterial infections extremely difficult to treat in cystic fibrosis patients, wearers of contact lenses, and burn victims. Jerry Nick, MD, Associate Professor of Medicine at National Jewish Health, and his... view more... (2009-03-24)

Discovery could aid fight against cystic fibrosis infection
Harvard Medical School researchers have discovered one way that a hardy disease-causing bacteria could be surviving in the lungs of chronically infected cystic fibrosis (CF) patients.   view more (2006-06-12)

NHLBI media availability: Treatment shows long-term benefits for cystic fibrosis patients
New research suggests that inhaling hypertonic saline, a water-based concentrated salt solution, could provide long-term benefits for lung health in patients with cystic fibrosis (CF).   view more (2006-01-19)

Mucous breakthrough in mice holds promise for cystic fibrosis
A London, Canada scientist studying cystic fibrosis (CF) has successfully corrected the defect which causes the overproduction of intestinal mucous in mice.   view more (2008-07-30)

Cystic Fibrosis Foundation announces positive early results for phase 2 clinical trial of VX-770
The Cystic Fibrosis Foundation announced today that VX-770, an oral drug in development that targets a basic defect in CF, showed promising results in an ongoing Phase 2a clinical trial for patients who carry the G551D mutation of CF. The drug is being developed by Vertex Pharmaceuticals Incorporated.   view more (2008-03-28)

Not only the gene itself, its abnormal regulation can also trigger short stature
A specific gene is particularly frequently involved in the development of short stature. Researchers in Heidelberg have now discovered that sequences of genetic material on the X and Y chromosome that regulate this gene are also crucial for growth in children.   view more (2009-08-26)

New Mayo Clinic MRI technology enables noninvasive liver diagnoses
Two recent Mayo Clinic studies have found that magnetic resonance elastography (MRE), a new imaging technique invented at Mayo Clinic, is an accurate tool for non-invasive diagnosis of liver diseases.   view more (2007-05-23)

Treat all patients with rare lung disease to prevent stroke, say doctors
Treatment should be offered to all people with a particular rare lung condition, regardless of whether or not they show symptoms of it, say researchers and doctors behind a new study published today.   view more (2007-11-05)

Special issue on cystic fibrosis in The Journal of Pediatrics
Cystic fibrosis is a common, fatal genetic disease in which a gene causes the body to produce abnormally thick, sticky mucus.   view more (2005-10-04)

PTC124 shows activity in cystic fibrosis; Phase 2 proof-of-concept data published in Lancet
New phase 2 data published today in The Lancet show that the investigational oral drug PTC124 demonstrates activity in nonsense-mutation cystic fibrosis (CF). The data show that treatment with PTC124 results in statistically significant improvements in the chloride channel function of patients with nonsense-mutation CF. The study was conducted at... view more... (2008-08-21)

EARLY PROMISE FOR TREATMENT OF PULMONARY HYPERTENSION (pp 1113, 1119)
Encouraging results of a randomised trial in this week’s issue of THE LANCET suggest that the drug bosentan could play an important future role in the treatment of pulmonary hypertension. Pulmonary hypertension (raised pressure in the blood vessels supplying the lungs) causes thickening of the right ventricle of the heart and can be... view more... (2001-10-03)

CT scans show patients with severe cases of H1N1 are at risk for developing acute pulmonary emboli
Researchers utilizing computed tomography (CT) scans have found that patients with severe cases of the H1N1 virus are at risk for developing severe complications, including pulmonary emboli (PE).   view more (2009-10-14)

Clots traveling from lower veins may not be the cause of pulmonary embolism in trauma patients
A report from a team of Massachusetts General Hospital (MGH) physicians calls into question the longstanding belief that pulmonary embolism (PE) - the life-threatening blockage of a major blood vessel in the lungs - is caused in trauma patients by a blood clot traveling from vessels deep within the legs or lower torso.   view more (2009-10-20)

Mayo Clinic's new imaging technology accurately identifies a broad spectrum of liver disease
A new study shows that an imaging technology developed by Mayo Clinic researchers can identify liver fibrosis with high accuracy and help eliminate the need for liver biopsies. Liver fibrosis is a common condition that can lead to incurable cirrhosis if not treated in time.   view more (2008-11-03)

Are blood thinners post-op killers?
New study shows that the use of powerful anticoagulants to prevent pulmonary embolism may actually lead to more deaths after surgery   view more (2008-04-01)

Rice breakthrough could prevent multiple fibrotic diseases
A scientific breakthrough at Rice University could lead to the first treatment that prevents the build-up of deadly scar tissue in a broad class of diseases that account for an estimated 45 percent of U.S. deaths each year.   view more (2007-01-19)

Researchers discover cell's 'quality control' mechanism
Researchers in Japan and Canada have discovered a key component of the quality control mechanism that operates inside human cells - sometimes too well. The breakthrough has significant implications for the development of new treatments for cystic fibrosis (CF) and some other hereditary diseases, the researchers say. Their results were published... view more... (2008-07-30)

Drug controls high-altitude illness
Acetazolamide, a drug used to manage fluid retention in heart failure, controlled the serious effects of pulmonary edema, the accumulation of fluid in lung tissue from high altitude, as well as improved brain oxygenation, during a randomized, double-blind and placebo-controlled study.   view more (2007-02-01)
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