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Immune Cells Current Events | Immune Cells News | 9

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Researchers testing virus-gene therapy combination against melanoma
Researchers at the Moores UCSD Cancer Center are injecting a modified herpes virus into melanoma tumors, hoping to kill the cancer cells while also bolstering the body's immune defenses against the disease.   view more (2009-07-02)

Head and neck cancer vaccine targets proteins to create immune response
Most attempts to create therapeutic cancer vaccines are based on custom-made approaches that use a patient's own tumor cells to generate a strong immune response against cancer. However, developing these kinds of personalized vaccines is time-consuming, expensive and often impractical.   view more (2007-04-18)

Research exposes new target for malaria drugs
The malaria parasite has waged a successful guerrilla war against the human immune system for eons, but a study in this week's Journal of Biological Chemistry has exposed one of the tricks malaria uses to hide from the immune proteins, which may aid in future drug development.    view more (2008-08-05)

NCI-Penn Collaboration Finds Targeted Immune Cells Shrink Tumors in Mice
Researchers have generated altered immune cells that are able to shrink, and in some cases eradicate, large tumors in mice.   view more (2009-02-11)

Melanoma treatment lesson
For some years ago now biochemotherapy has replaced chemotherapy for the treatment of melanomas. In biochemotherapy, together with chemotherapuetic agents, substances that activate the patient's immune system are used with the objective of obtaining a reinforced immune system in order to help the patient overcome the illness.   view more (2005-01-04)

University of Pennsylvania Researchers Identify Gatekeeper Involved in Chronic Inflammatory Diseases
he road to many an inflammatory disease is guarded by a cytokine messenger protein called interleukin-27, according to researchers from the University of Pennsylvania School of Veterinary Medicine. Chronic inflammation results when the immune system becomes over stimulated and begins attacking healthy tissue in excess.   view more (2006-08-22)

What is potentially pathogenic role of anti-tTG IgA in the development of celiac disease?
The recent detection of antibodies in celiac patients specific for deamidated gliadin peptides (DGP), the product of tTG binding to gliadin peptides, provides an opportunity to address the correlation between the production of anti-tTG IgA and the antibodies against DGP in celiac patients.   view more (2009-02-23)

Scientists find a key to immune system's ability to remember
Its ability to accurately catalog and recall long past encounters with viruses, bacteria and other pathogens is why we only get the measles or chicken pox once, and is why exposure to deactivated virus particles in vaccines confers protection from disease.   view more (2006-10-24)

University of Pittsburgh discovers genetic 'shut down' trigger in healthy immune cells
A fundamental genetic mechanism that shuts down an important gene in healthy immune system cells has been discovered that could one day lead to new therapies against infections, leukemia and other cancers.   view more (2007-05-10)

Gliomas exploit immune cells of the brain for rapid expansion
Gliomas are among the most common and most malignant brain tumors. These tumors infiltrate normal brain tissue and grow very rapidly. As a result, surgery can never completely remove the tumor.   view more (2009-07-17)

Cancer immunoresistance linked to loss of tumor suppressor gene
Cancer immunoresistance may be partially due to loss of a well-known tumor suppressor gene, according to new research led by Andrew T. Parsa, MD, PhD, assistant professor of neurological surgery at the University of California, San Francisco.   view more (2006-12-11)

Research Will Push Forward Fight Against Leukaemia
A project which aims to make laboratory-grown leukaemia cells change form and then be used to prime a patient's own immune system to kill off malignant cells has begun in Edinburgh. If successful, the study could give clinicians a way of destroying residual leukaemic cells which are undetectable by microscope. The findings could be helpful in the... view more... (2002-10-25)

Jefferson scientists find protein helps pancreatic cancer cells evade immune system and spread
A protein that helps prevent a woman's body from rejecting a fetus may also play an important role in enabling pancreatic cancer cells to evade detection by the immune system, allowing them to spread in the body.   view more (2008-01-11)

Immune cells fighting chronic infections become progressively 'exhausted,' ineffective
A new study of immune cells battling a chronic viral infection shows that the cells, called T cells, become exhausted by the fight in specific ways, undergoing profound changes that make them progressively less effective over time.   view more (2007-10-19)

OHSU researchers demonstrate how white blood cells cannibalize virus-infected cells
Researchers at the Vaccine and Gene Therapy Institute (VGTI) at Oregon Health & Science University have demonstrated how certain white blood cells literally eat virus-infected cells while fighting disease at the microscopic level.   view more (2006-10-03)

Pioneering discoveries recognized in field of immune deficiencies in children (so-called bubble children)
Professor Alain Fischer from Paris is being awarded the prestigious M'Īrta Philipson Prize in Children's Medicine from Karolinska Institutet in Sweden for his research on immune deficiencies in children. Many children are particularly susceptible to infections and often contract ear inflammations, for example. Every year a few children are born... view more... (2003-01-27)

When acute hepatitis develops into chronic hepatitis
To achieve this, Carlos A. Guzmán, Head of the "Vaccinology and Applied Microbiology" working group and Robert Geffers, Head of the "Gene Expression Analysis" platform, examined the incidence and species of special defence cells, T helper cells, along with their role in the development of the disease in conjunction with... view more... (2009-02-17)

Goodbye needle, hello smoothie
Instead of a dreaded injection with a needle, someday getting vaccinated against disease may be as pleasant as drinking a yogurt smoothie.   view more (2009-03-18)

UCLA researchers observe how the immune system recognizes and responds to cancer
Using positron emission tomography (PET) imaging, researchers at UCLA's Jonsson Cancer Center were able to observe-in real time-how the immune system initially recognizes cancer and mobilizes to fight the disease.   view more (2005-11-15)

UCLA researchers develop T-cells from human embryonic stem cells
Researchers from the UCLA AIDS Institute and the Institute for Stem Cell Biology and Medicine have demonstrated for the first time that human embryonic stem cells can be genetically manipulated and coaxed to develop into mature T-cells, raising hopes for a gene therapy to combat AIDS.   view more (2006-07-05)
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