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Tumor wizardry wards off attacks from the immune system
Like the fictional wizard Harry Potter, some cancerous tumors seem capable of wrapping themselves in an invisibility cloak. Researchers at Washington University School of Medicine in St. Louis have found that pancreatic tumors hide from the body's immune surveillance by surrounding themselves with cells that make it hard for the immune system to... view more... (2006-07-17)
Case Western Reserve University researchers find protein associated with brain cell death
Neuroscientists at the Case Western Reserve University School of Medicine have found evidence of which protein in the brain's immune cells triggers a cascade of reactions that produces unregulated free radical production that eventually leads to the neural cell death found in Alzheimer's disease. view more (2006-07-19)
Research exposes new target for malaria drugs
The malaria parasite has waged a successful guerrilla war against the human immune system for eons, but a study in this week's Journal of Biological Chemistry has exposed one of the tricks malaria uses to hide from the immune proteins, which may aid in future drug development. view more (2008-08-05)
Helicobacter pylori - the key behind its recognition is somewhere else
The first step against infection is the detection of microorganisms capable of causing disease. This is done through the recognition of molecular structures not shared by the host, but also present in other harmless or even useful microbes. A question that has puzzled scientists for many years is how the host knows exactly against which microbes... view more... (2004-10-29)
NIH scientists find a novel mechanism that controls the development of autoimmunity
Scientists at the National Institutes of Health (NIH) have found a mechanism in the immune systems of mice that can lead to the development of autoimmune disease when turned off. view more (2008-08-14)
Dynamic duo: Combination therapy reverses type 1 diabetes
Researchers have now carefully crafted a combination therapy that reverses recent-onset type 1 diabetes in 2 animal models of disease. view more (2006-04-21)
Insight on fruit fly immune system could lead to new types of vaccines, Stanford researchers say
The tiny fruit fly has a lot to teach humans. Researchers at the Stanford University School of Medicine have found for the first time that flies' primitive immune systems may develop long-term protection from infection, an ability previously thought impossible for insects. view more (2007-03-09)
Discovery of a 'molecular switch' could lead to new ways of treating infection, including MRSA
The discovery of a 'molecular switch' could lead to new ways of treating infections such as MRSA, and inflammatory diseases like arthritis. view more (2005-04-26)
Researchers identify key protein in immune response to malaria and TB
An international team of researchers has identified a key protein involved in the immune system's response to malaria, tuberculosis (TB) and a number of other infectious diseases. The insights suggest possible new therapies to tackle these major global diseases. view more (2007-03-27)
Natural mechanism for immune suppression paves way for cancer trials
A natural mechanism pirated by tumors and HIV to evade the immune response is opening the door to better treatment for these conditions, researchers say. view more (2007-03-29)
Common diabetes drug may 'revolutionize' cancer therapies
Researchers at McGill University and the University of Pennsylvania have discovered that a widely used anti-diabetic drug can boost the immune system and increase the potency of vaccines and cancer treatments. view more (2009-06-04)
Helicobacter pylori can multiply in autophagic vesicles
Helicobacter pylori, a Gram-negative, flagellated, microaerophilic bacterium, can selectively colonize in the human stomach. Its infection is widespread throughout the world, and is present in about 50% of the global human population with 80% in developing countries and 20-50% in industrialized countries. view more (2009-01-28)
Mouse experiments shed light on age effects in arthritis
Older mice are more susceptible to proteoglycan-induced arthritis (PGIA). Researchers writing in BioMed Central's open access journal Immunity & Ageing have shown, for the first time, that young mice are completely resistant, but become fully susceptible to the disease with age. view more (2009-06-11)
Novel method to create personalized immunotherapy treatments
Argos Therapeutics and Université de Montréal today announced the presentation of new information on Argos'process for developing dendritic cell-based immunotherapies for HIV. view more (2008-08-06)
Promising treatment target found in Hodgkin lymphoma
Dana-Farber Cancer Institute scientists have identified a protein that prevents the body's immune system from recognizing and attacking Hodgkin lymphoma cells. view more (2007-07-31)
New lab mice pave way for novel studies of human infection
A new type of laboratory mouse developed at UT Southwestern Medical Center can fight certain infections the same way humans do, making the rodents very useful for novel studies of human-pathogen interaction and developing disease therapies. view more (2006-10-23)
Researchers Learn Why Immune System's Watch Dogs Howl
Toll-like receptors are the guard dogs of the immune system, sniffing out bacteria and viruses then activating the body's immune system for an attack on these invaders. view more (2007-08-03)
USC researchers discover novel way to develop tumor vaccines
Researchers at the University of Southern California (USC) have uncovered a new way to develop more effective tumor vaccines by turning off the suppression function of regulatory T cells. view more (2008-03-03)
Exposure to PCBs May Reduce the Effectiveness of Vaccines in Children
New epidemiological evidence suggests that exposure to environmental pollutants may have an adverse impact on immune responses to childhood vaccinations. view more (2006-08-23)
Effective HIV control may depend on viral protein targeted by immune cells
An effective response of the immune system's 'killer' T cells against infection with HIV may depend on exactly which viral protein is targeted, according to an international group of researchers. view more (2006-12-18)
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