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Malaria and Epstein-Barr virus linked to pediatric cancer in Africa
Endemic Burkitt lymphoma is a form of cancer that accounts for up to 74% of malignant disorders in children in equatorial Africa. Malaria and Epstein-Barr virus (EBV) are known cofactors in its development, but to date, their relative contribution has not been well understood. view more (2007-06-08)
Protein research could lead to new meningitis vaccine
New technology is leading to a vaccine against Group B Streptococci (GBS), a common cause of meningitis as well as a frequent cause of pneumonia in newborns. Key proteins have been found that can kick-start the immune system to fight these bacteria, scientists heard today (Tuesday 09 April 2002) at the spring meeting of the Society for General... view more... (2002-04-03)
Immune exhaustion driven by antigen in chronic viral infection
A main reason why viruses such as HIV or hepatitis C persist despite a vigorous initial immune response is exhaustion. The T cells, or white blood cells, fighting a chronic infection eventually wear out. view more (2009-05-14)
Hospital infections cost $1 billion in lost bed days
Infections caught in hospital are costing the Australian healthcare system more than 850,000 lost bed days, according to a new study by Queensland University of Technology. view more (2009-09-02)
Herpesvirus: To Vaccinate or Not To Vaccinate Scientists Weigh Risks and Benefits
Dr. Marcia Blackman and her research team at the Trudeau Institute have followed up on an intriguing report published in the journal Nature in May 2007 by Dr. Herbert Virgin, et al., showing that mice persistently infected with certain forms of herpesvirus, which can establish lifelong latent infections, are resistant to infection with bacterial... view more... (2009-02-13)
Protein identified that turns off HIV-fighting T cells
In HIV-infected patients the body's immune system is unable to fight off the virus. A new study to be published online on November 10th in the Journal of Experimental Medicine shows that T cells in HIV-infected individuals express a protein called TIM-3, which inactivates their virus killing capacity. view more (2008-11-10)
HORIZONTAL GENE TRANSFER COULD RESULT IN EMERGENCE OF METICILLIN-RESISTANT STAPHYLOCOCCUS AUREUS (p 1674)
A baby who developed meticillin-resistant staphylococcus aureus (MRSA) infection without exposure to MRSA carriers suggests an alternative model for the acquisition of this virulent staphylococcal infection. In a research letter in this week's issue of THE LANCET, the authors conclude that a new MRSA genotype was formed in vivo by exchange of the... view more... (2001-05-23)
Immune exhaustion in HIV infection
As HIV disease progresses in a person infected with the HIV virus, a group of cells in the immune system, the CD8+ T lymphocytes, become "exhausted," losing many of their abilities to kill other cells infected by the virus. view more (2008-05-06)
FDA ignores critical information on home HIV tests
The FDA is ignoring critical information in deciding whether to approve an over-the-counter, rapid HIV test for home use. view more (2009-05-29)
Salmonella's sweet tooth predicts its downfall
For the first time UK scientists have shown what the food poisoning bug Salmonella feeds on to survive as it causes infection: glucose. view more (2009-05-20)
Combination vaccine protects monkeys from ebola and Marburg viruses
An experimental, combination vaccine against Ebola and Marburg viruses using virus-like particles (VLPs) provides complete protection against infection in monkeys. view more (2008-02-27)
Substantial Increase In Survival After Introduction Of Highly Active Antiretroviral Therapy For HIV-1 Infection (p 1267)
Research published in this week's issue of THE LANCET highlights the substantial increased survival for people with HIV-1 since the introduction of highly active antiretroviral therapy (HAART) in 1997. However the study also shows a shift in risk profiles compared with earlier data-people over 45 years no longer appear to have reduced survival... view more... (2003-10-15)
HIV's effect on white blood cells questioned by new research
Scientists have refuted a longstanding theory of how HIV slowly depletes the body's capacity to fight infection, in new research published today. view more (2007-05-22)
Stress signals link pre-existing sickness with susceptibility to bacterial infection
Mitochondrial diseases disrupt the power generating machinery within cells and increase a person's susceptibility to bacterial infection, particularly in the lungs or respiratory tract. view more (2009-07-28)
Mosquito immune system examined
Mosquitoes employ the same immune factors to fight off bacterial pathogens as they do to kill malaria-causing Plasmodium parasites, according to a study by researchers at the Johns Hopkins Bloomberg School of Public Health. view more (2006-06-09)
Chronic fatigue syndrome linked to stomach virus
Chronic fatigue syndrome, also known as ME (myalgic encephalitis), is linked to a stomach virus, suggests research published ahead of print in Journal of Clinical Pathology. view more (2007-09-14)
Beating hospital yeast infection
Increasing numbers of critically ill patients develop fungal or yeast infections, which are associated with high mortality. Now a review published in the online open access journal, Critical Care, compares treatments involving single-drug antifungal prophylaxis (SAP) or a multi-drug regimen of selective digestive tract decontamination (SDD) and... view more... (2007-12-06)
STDs disrupt genetic bottleneck that usually constrains HIV infection
Scientists have shown that HIV faces a genetic "bottleneck" when the virus is transmitted heterosexually from one person to another, by way of the genital mucosa. view more (2009-01-23)
Change in guidelines could help eliminate TB in US
To eliminate tuberculosis (TB) in the United States, current guidelines should be changed to reclassify all foreign-born residents from high-incidence countries as "high-risk," regardless of the amount of time they have lived in the U.S. view more (2007-01-03)
Guidelines needed to prevent spread of infection in European hospitals
National and European guidelines to control the spread of vancomycin resistant enterococci should be drawn up before these bacteria become endemic in European hospitals, argue researchers in this week's BMJ. Vancomycin resistant bacteria have a low virulence but can cause serious infections in transplant patients or those in intensive care units.... view more... (2002-03-13)
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