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High insulin levels impair intestinal metabolic function
Nutritional scientists at the University of Alberta are the first to establish a connection between high insulin levels and dysfunction of intestinal lipid metabolism in an animal model. view more (2007-04-25)
Testing for insulin without the pitter-patter of little feet
In the January issue of Clinical Biochemistry, scientists and physicians with the Physicians Committee for Responsible Medicine (PCRM) outline the method used to develop a cruelty-free ELISA for human insulin that uses monoclonal antibodies produced by cells cultured in an animal-serum-free medium. view more (2007-01-31)
If the diabetes has a direct carcinogenetic effect?
The association of DM2 with solid tumors, and particularly with HCC, has been long suspected and several studies have reported increased mortality rates for neoplastic diseases in patients with DM2. view more (2008-10-29)
Low-carb diet better than low-fat diet at improving metabolic syndrome
Diabetes and cardiovascular disease associated with it. In an article published today in the open access journal Nutrition & Metabolism, Jeff Volek and Richard Feinman review the literature and show that the features of metabolic syndrome are precisely those that are improved by reducing carbohydrates in the diet. view more (2005-11-16)
Bypassing the insulin highway
An immune cell known as a neutrophil releases a protein that can suppress glucose production in the liver -without targeting insulin, researchers have found. view more (2008-04-28)
Study suggests use of stem cell transplantation is beneficial treatment of type 1 diabetes
A therapy that includes stem cell transplantation induced extended insulin independence in patients with type 1 diabetes mellitus. view more (2007-04-11)
Insulin analogue glargine possibly increases cancer risk
The risk of cancer possibly increases if patients with diabetes use the long-acting insulin analogue glargine instead of human insulin. view more (2009-06-29)
Insulin research builds on Nobel Laureate's work
Scientists have seen for the first time a key step in the complex molecular processes whereby pancreas cells release insulin into the bloodstream. view more (2006-05-08)
Early Promise Of New Treatment For Type 2 Diabetes (p 824)
Authors of a pilot study in this week's issue of THE LANCET suggest that a naturally occurring intestinal hormone could be beneficial for the future treatment of type 2 diabetes. Type 2 diabetes affects an estimated 10% of adults over 60 years of age, and has recently been reported in teenage children. Treatment for the disorder usually includes... view more... (2002-03-06)
UNC scientists turn human skin cells into insulin-producing cells
Researchers at the University of North Carolina at Chapel Hill School of Medicine have transformed cells from human skin into cells that produce insulin, the hormone used to treat diabetes. view more (2008-09-18)
Potential preventative therapy for Type 1 diabetes
Scientists believe they may have found a preventative therapy for Type 1 diabetes, by making the body's killer immune cells tolerate the insulin-producing cells they would normally attack and destroy, prior to disease onset. view more (2009-04-29)
microRNA-mediated metabolism
In the February 15th issue of G&D, Drs. Aurelio Teleman and Stephen Cohen (EMBL) assign one of the first biological functions to an animal microRNA: the microRNA miR-278 regulates energy homeostasis in Drosophila. view more (2006-02-15)
Fat on chest and upper back increases risk of insulin resistance
Upper trunk fat -- deposits of fat on the chest and back -- is associated with an increased risk of insulin resistance, a condition that is a precursor of type 2 diabetes, according to a study led by researchers at the San Francisco VA Medical Center (SFVAMC). view more (2007-08-20)
Apelin to rescue diabetics
Sugar is naturally present in the blood in the form of glucose and is stored in the liver or adipose tissue (fat) thanks to the action of insulin. Glucose is stored or directly used to ensure satisfactory function of the heart, brain and so on according to the body's demands. view more (2008-11-05)
New Model Helps Diabetes Research
Scientists at the Babraham Institute are developing new methods to aid research into the causes of diabetes, a condition suffered by around 2.5 million people in the UK. A new study, published in The Journal of Clinical Investigation, describes an effective model of a rare form of the disease called transient neonatal diabetes mellitus (TNDM),... view more... (2004-08-17)
Alcohol not likely to protect against type II diabetes
Alcohol is unlikely to protect drinkers from the risk of developing adult onset (type II) diabetes, concludes research in the Journal of Epidemiology and Community Health. Alcohol seems to confer only a slight advantage in moderate drinkers, the research shows. To date, the effects of light to moderate alcohol consumption on the risk of developing... view more... (2002-06-20)
Fat cells send message that aids insulin secretion
The body's fat cells help the pancreas do its job of secreting insulin, according to research at Washington University School of Medicine in St. Louis. view more (2007-11-07)
Not all fat created equal
It has long been known that type 2 diabetes is linked to obesity, particularly fat inside the belly. Now, researchers at the Joslin Diabetes Center have found that fat from other areas of the body can actually reduce insulin resistance and improve insulin sensitivity. view more (2008-05-07)
Insulin boost restores muscle growth in elderly
When most people think of insulin, they think of diabetes - a disease that arises when, for one reason or another, insulin can't do the critical job of helping the body process sugar. view more (2009-09-28)
Ghrelin: A player in diabetes but not obesity?
Ghrelin, a hormone long considered a key player in obesity, may instead take a major role in maintaining the balance between insulin and glucose and the development of diabetes. view more (2006-05-10)
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