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Joslin researchers uncover potential role of leptin in diabetes
A new Joslin-led study has shown that leptin, a hormone known mainly for regulating appetite control and energy metabolism, plays a major role in islet cell growth and insulin secretion.   view more (2007-10-02)

Insulin research points way to better diabetes treatments
New research that significantly improves our understanding of how insulin interacts with cells in the human body is published today.    view more (2010-01-26)

First functional insulin-binding protein in invertebrates
Insulin-like growth factor (IGF) signaling that helps to regulate mammals' growth, metabolism, reproduction and longevity is well documented.   view more (2008-04-15)

Discovery supports theory of Alzheimer's disease as form of diabetes
Insulin, it turns out, may be as important for the mind as it is for the body. Research in the last few years has raised the possibility that Alzheimer's memory loss could be due to a novel third form of diabetes.   view more (2007-09-27)

Phthalates now linked to fat, related health risks
Exposure to phthalates, a common chemical found in everything from plastics to soaps, already has been connected to reproductive problems and now, for the first time, is linked to abdominal obesity and insulin resistance in adult males, according to a study by the University of Rochester Medical Center.   view more (2007-03-15)

Researcher explores why smoking increases the risk of heart disease and strokes
Researchers at Charles Drew University of Medicine and Science in Los Angeles and Western University of Health Sciences in Pomona have discovered a reason why smoking increases the risk of heart disease and strokes.   view more (2009-06-12)

HSPH researchers discover natural inflammation-fighting mechanism in body-fat cells
Scientists have discovered a previously unknown molecular signaling pathway in body fat cells that normally acts to suppress harmful inflammation. Cellular stress caused by obesity, however, can override this protective function and convert the pathway into a trigger of chronic inflammation that raises the risk of insulin resistance, diabetes, and... view more... (2008-06-04)

Scientists find gene in obese mice that increases type 2 diabetes
In a painstaking set of experiments in overweight mice, scientists from the University of Wisconsin-Madison have discovered a gene that appears to play an important role in the onset of type 2 diabetes.   view more (2006-05-08)

Overweight Hispanic children shown to have vascular inflammation
Overweight Hispanic children with normal blood glucose (sugar) levels showed elevated markers for blood vessel inflammation that may predispose them to developing both type 2 diabetes and cardiovascular disease, says a new study led by researchers from the Joslin Diabetes Center.   view more (2008-02-27)

High insulin levels impair intestinal metabolic function
Nutritional scientists at the University of Alberta are the first to establish a connection between high insulin levels and dysfunction of intestinal lipid metabolism in an animal model.   view more (2007-04-25)

Insulin analogues: What's all the fuss?
Insulin analogues are modified human insulins developed to address the limitations of human insulins which do not always respond to increased blood glucose levels in the same way as insulin that is naturally secreted by the body.   view more (2009-02-17)

Insulin therapy shown to treat early experimental diabetic retinopathy
Researchers will present study results that indicate that subconjunctivally delivered insulin ameliorates degenerative and inflammatory responses in diabetic rat retinas at the Association for Research in Vision and Ophthalmology (ARVO) 2007 Annual Meeting in Fort Lauderdale, Fla.   view more (2007-05-10)

New Research on Type 2 Diabetes by TCD Researchers Could Benefit Young Adults with the Condition
New research on Type 2 diabetes by Trinity College Dublin researchers could benefit young adults (aged 18-25 years) with the condition.   view more (2010-02-02)

Widespread uncontrolled use of antibiotics to prevent anthrax will lead to resistance
Giving antibiotics to large numbers of potentially exposed individuals to prevent anthrax will lead to resistance, according to researchers from Liverpool in this week's BMJ. As such, it is essential that they are used carefully and according to national guidelines. Although generally safe, the antimicrobial drug ciprofloxacin, which has been... view more... (2001-10-31)

Soy protein reduces effects of diabetes on liver
A group of researchers from Mexico has discovered that a diet rich in soy protein may alleviate fatty liver, a disease which often accompanies diabetes.   view more (2005-09-07)

Newly identified genes influence insulin and glucose regulation
An international research consortium has found 13 new genetic variants that influence blood glucose regulation, insulin resistance, and the function of insulin-secreting beta cells in populations of European descent. Five of the newly discovered variants increase the risk of developing type 2 diabetes, the most common form of diabetes.   view more (2010-01-18)

Moderate use averts failure of type 2 diabetes drugs in animal model
Drugs widely used to treat type 2 diabetes may be more likely to keep working if they are used in moderation, researchers at Washington University School of Medicine in St. Louis have found in a study using an animal model.   view more (2008-10-28)

Developmental changes in adolescence raise men's heart disease risk
Normal developmental changes during the teenage years leave young adult men at higher risk of heart disease than their female counterparts, researchers report in Circulation: Journal of the American Heart Association.   view more (2008-04-22)

Old diabetes drug teaches experts new tricks
Research from the Johns Hopkins Children's Center reveals that the drug most commonly used in type 2 diabetics who don't need insulin works on a much more basic level than once thought, treating persistently elevated blood sugar - the hallmark of type 2 diabetes - by regulating the genes that control its production.   view more (2009-05-15)

Can berberine enhance glucose-stimulated insulin secretion in rat islets?
The therapeutical actions of berberine on diabetes have been well studied. Previous researches show that berberine modulates cholesterol through increasing low-density lipoprotein receptor mRNA stability, reduces body adiposity and increases insulin sensitivity partly through activating AMP-activated protein kinase and improves glucose metabolism... view more... (2008-11-03)
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