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A new mechanism regulates type I interferon production in white blood cells
A study from a team of researchers led by Dr. Andrew P. Makrigiannis, Director of the Molecular Immunology Research Unit at the IRCM, has identified a new mechanism regulating interferon production.   view more (2009-01-13)

Interferons For Treatment Of SARS? (p 293)
Authors of a research letter in this week's issue of THE LANCET suggest that recombinant interferons - synthetic versions of naturally occurring compounds of the immune system - could be a an effective treatment for Severe Acute Respiratory Syndrome (SARS). Although antivirals are probably essential for the treatment of SARS-CoV infection, the... view more... (2003-07-23)

High-dose Interferon Beta-1B On Alternate Days Could Offer Increased Clinical Benefit For People With Multiple Sclerosis (p 1453)
A study published in this week's issue of THE LANCET suggests that high-dose interferon beta-1b administered every other day is more effective than interferon beta-1a once a week for people with multiple sclerosis (MS). There are three interferon beta therapies known to be effective in reducing MS symptoms: interferon beta-1a 30 mcg administered... view more... (2002-04-24)

Study details hepatitis C ability to block immune system response
Hepatitis C virus (HCV) is a worldwide public health problem. The World Health Organization estimates that 170 million people worldwide are chronically infected and that between 3-4 million are newly infected annually.   view more (2006-05-19)

Government money for multiple sclerosis patients could be better spent
The National Institute for Clinical Excellence (NICE) has announced that neither interferon beta nor glatiramer can be recommended for multiple sclerosis in the NHS. However, the UK government plans to make these drugs available through a risk sharing scheme, despite limited evidence of clinical and cost effectiveness. Researchers in this week's... view more... (2003-02-12)

Detection Of Antibodies Could Identify MS Patients Who Do Not Respond Well To Interferon Beta (P1184)
Danish research published in this week's issue of THE LANCET highlights how the detection of antibodies to interferon beta-the first choice treatment for multiple sclerosis patients-could be important in identifying patients who do not respond well to interferon beta, with implications for the provision of alternative drug therapy. Interferon beta... view more... (2003-10-08)

Newfound roadblock to interferon effectiveness against malignant melanoma
Researchers have uncovered a significant contributing factor to interferon resistance of malignant melanoma cells.   view more (2005-09-22)

BUDGET FOR INTERFERON BETA FOR MS SUFFERERS WOULD BE BETTER SPENT ON IMPROVED SUPPORTIVE CARE
Dr Raeburn Forbes from Ninewells Hospital and Medical School in Dundee along with colleagues from Argyll and Clyde Health Board and the Scottish Health Purchasing Information Centre studied 132 people with secondary progressive multiple sclerosis and the estimated effect of treating them with interferon beta-1b against existing best practice... view more... (1999-12-08)

Genetic breakthrough supercharges immunity to flu and other viruses
Researchers at McGill University have discovered a way to boost an organism's natural anti-virus defences, effectively making its cells immune to influenza and other viruses.   view more (2008-02-14)

The right messenger for a healthy immune response
Researchers from the Molecular Immunology group at the Helmholtz Centre for Infection Research (HZI) in Braunschweig, Germany have now shown that Beta-Interferon also plays a crucial role during an immune response: without Beta-Interferon immune cells are unable to show "wanted posters" of pathogens to other cells.   view more (2009-07-20)

New hope for Hepatitis C research
The mystery surrounding Hepatitis C, a disease that affects millions of people worldwide, is one step closer to being solved.   view more (2006-08-11)

Stem cells: Deathly awakening by interferon
After injuries with blood loss, the body quickly needs to restore the vital blood volume. This is accomplished by a special group of stem cells in the bone marrow.   view more (2009-02-12)

Researchers prolong the plasma half-life of biopharmaceutical proteins
Many biopharmaceuticals comprise small proteins that are quickly eliminated from the body. Scientists at the Technische Universitaet Muenchen (TUM) combine such small proteins with a kind of molecular balloon that swells and thus prolongs the half-life of the proteins in the body.   view more (2009-09-21)

Another hope for multiple sclerosis patients. Improved Interferon-beta patent recently granted by
Blurred vision, weak limbs, tingling sensations, unsteadiness and fa-tigue are the symptoms of one of the most common diseases of the central nervous system, the multiple sclerosis (MS). It is estimated that MS currently affects over 2,500,000 people worldwide. There is new hope for MS patients: The protein Interferon-beta, which is produced in... view more... (2003-08-06)

Adding steroid drug to MS treatment may reduce disease activity
Using a steroid drug for multiple sclerosis (MS) in addition to an MS drug may reduce the amount of disease activity more than using the MS drug alone.   view more (2009-04-30)

Study shows combination of immune substances to be safe
New research has shown that the immune-stimulating hormone known as interleukin-12 (IL-12) can safely be administered with interferon, another immune-system protein, as an experimental therapy for some cancers.   view more (2005-12-12)

Good news for some hard-to-treat hepatitis C patients
In a multi-center trial led by a Saint Louis University researcher, investigators found that a new combination therapy of daily consensus interferon and ribavirin helps some hepatitis C patients who have not responded to previous treatment.   view more (2009-06-16)

Interesting lead in the treatment of Ewing`s sarcoma
Research scientists at INSERM, CNRS and the Institut Curie, in collaboration with physicians, have used a mouse model to demonstrate the efficacy of an innovative therapeutic approach to Ewing`s sarcoma: the combination of human interferon (alpha or beta) and a common anti-tumor agent, ifosfamide. Their results were published in the November 2002... view more... (2002-10-31)

New discovery gives tuberculosis vaccine a shot in the arm
A new article appearing in the March 2009 issue of the Journal of Leukocyte Biology may lead to improvements in the efficacy of the current tuberculosis vaccine.   view more (2009-02-27)

Scientists shine new light on inflammatory diseases
Investigators at Hospital for Special Surgery have identified a new mechanism involved in the pathogenesis of inflammatory diseases such as rheumatoid arthritis.   view more (2008-03-17)
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