Interleukin-12 Current Events | Interleukin-12 News | 5
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Inflammation markers linked more with fatal than nonfatal cardiovascular events in elderly
A study published this week in the open access journal PLoS Medicine shows that for elderly people at risk of cardiovascular disease, the presence of inflammatory markers in the blood can identify that an individual is at a higher risk of a fatal rather than a non-fatal heart attack or stroke. view more (2009-06-23)
Genes may determine success of anti-inflammatory therapy for rheumatoid arthritis
Small genetic differences may explain why the same drug works well in one individual but not in another. These genetic variations could be exploited to develop individually tailored treatment programmes for rheumatoid arthritis, Swedish researchers said today. Speaking at the Press Conference during EULAR 2001, the prestigious annual congress of... view more... (2001-06-14)
New engineered drug may offer prolonged arthritis relief
Researchers at Duke University have devised a new way to significantly prolong the effects of an anti-inflammatory drug, potentially making it useful for providing longer-lasting treatment for osteoarthritis, the most common form of arthritis. view more (2006-10-16)
Tocilizumab study offers new hope for children with arthritis
A new study has confirmed significant improvements after treatment with tocilizumab amongst children with systemic juvenile idiopathic arthritis (sJIA), who do not tolerate or have an inadequate response to conventional therapies. view more (2006-06-23)
Immunity in social amoeba suggests ancient beginnings
Finding an immune system in the social amoeba (Dictyostelium discoideum) is not only surprising but it also may prove a clue as to what is necessary for an organism to become multicellular, said the Baylor College of Medicine researcher who led the research that appears today in the journal Science. view more (2007-08-03)
LSUHSC researcher identifies new target to prevent fatal flu lung complication
Research led by Dr. Jay Kolls, Professor and Chairman of Genetics at LSU Health Sciences Center New Orleans, has identified a therapeutic target for acute lung injury resulting in acute respiratory distress syndrome, a highly fatal complication of influenza infection. view more (2009-09-30)
Pitt study finds molecular link between insulin resistance and inflammation
An exploration of the molecular links between insulin resistance and inflammation may have revealed a novel target for diabetes treatment, say scientists at the John G. Rangos Sr. Research Center, Children's Hospital of Pittsburgh of UPMC. view more (2009-08-27)
New tests needed to predict cardiovascular problems in older people more accurately
A long-standing system for assessing the risk of cardiovascular disease amongst older people should be replaced with something more accurate, according to a study published today on bmj.com. view more (2009-01-09)
VCU Massey Cancer Center and VCU Institute of Molecular Medicine Researchers Publish Findings of a New Chemoprevention Gene Therapy That Kills Pancreatic Cancer Cells
Researchers at the Virginia Commonwealth University Massey Cancer Center and the VCU Institute of Molecular Medicine have published findings that implicate a new chemoprevention gene therapy (CGT) for preventing and treating pancreatic cancer, one of the most lethal and treatment-resistant forms of cancer. view more (2008-08-06)
Markers of inflammation and blood-clotting tied to hazards of intermittent HIV treatment
Episodic treatment of HIV/AIDS with antiretroviral drugs increases the overall risk of death when compared with continuous antiretroviral treatment (ART), but the reasons why have been unknown. view more (2008-10-22)
Study suggests that inflammation may be the link between extreme sleep durations and poor health
A study in the Feb. 1 issue of the journal SLEEP shows that sleep duration is associated with changes in the levels of specific cytokines that are important in regulating inflammation. The results suggest that inflammation may be the pathway linking extreme sleep durations to an increased risk for disease. view more (2009-02-02)
Scientists remove amyloid plaques from brains of live animals with Alzheimer's disease
A breakthrough discovery by scientists from the Mayo Clinic in Jacksonville, FL, may lead to a new treatment for Alzheimer's Disease that actually removes amyloid plaques-considered a hallmark of the disease-from patients' brains. view more (2009-10-15)
First multinational study of Tocilizumab reports in
Nearly half (43.9%) of rheumatoid arthritis (RA) patients receiving tocilizumab 8mg/kg, in addition to ongoing methotrexate therapy experienced a 50% (ACR50) improvement in symptoms at 24 weeks and more than one fifth achieved a 70% symptom improvement. view more (2007-06-18)
Hopkins scientists link immune response to 'ghost' parasites and severely congested sinuses
Although it's unclear why it's so, scientists at Johns Hopkins have linked a gene that allows for the chemical breakdown of the tough, protective casing that houses insects and worms to the severe congestion and polyp formation typical of chronic sinusitis. view more (2006-09-07)
Some smokers have genetic predisposition to develop COPD, research shows
Some people have a genetic variation that makes them more susceptible to chronic obstructive pulmonary disease (COPD) if they smoke tobacco, according to new research from Wake Forest University School of Medicine and colleagues. view more (2007-07-12)
Lack of sleep could be more dangerous for women than men
Women who get less than the recommended eight hours sleep a night are at higher risk of heart disease and heart-related problems than men with the same sleeping patterns. view more (2009-07-02)
Melanoma treatment lesson
For some years ago now biochemotherapy has replaced chemotherapy for the treatment of melanomas. In biochemotherapy, together with chemotherapuetic agents, substances that activate the patient's immune system are used with the objective of obtaining a reinforced immune system in order to help the patient overcome the illness. view more (2005-01-04)
Possible solution to Group B streptococci infection in newborn infants
The search for a vaccine against group B streptococci Group B streptococci are one of the leading causes of infection in newborn infants, causing pneumonia, septicaemia or meningitis. view more (2007-02-09)
Finding suggests novel ways to boost vaccination or natural defenses
Our bodies rely on the production of potent, or 'high affinity', antibodies to fight infection. The process is very complex, yet Sydney scientists have discovered that it hinges on a single molecule, a growth factor, without which it cannot function. view more (2008-07-08)
Study shows combination of immune substances to be safe
New research has shown that the immune-stimulating hormone known as interleukin-12 (IL-12) can safely be administered with interferon, another immune-system protein, as an experimental therapy for some cancers. view more (2005-12-12)
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