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RNA-associated introns guide nerve-cell channel production
Researchers at the University of Pennsylvania School of Medicine have discovered that introns, or junk DNA to some, associated with RNA are an important molecular guide to making nerve-cell electrical channels. view more (2008-02-06)
Carnegie Mellon University research reveals how cells process large genes
Important messages require accurate transmission. Big genes are especially challenging because they combine many coding segments (exons) that lie between long stretches of non-coding elements (introns). view more (2005-08-24)
Yale scientists visualize the machinery of mRNA splicing
Recent research at Yale provided a glimpse of the ancient mechanism that helped diversify our genomes; it illuminated a relationship between gene processing in humans and the most primitive organisms by creating the first crystal structure of a crucial self-splicing region of RNA. view more (2008-04-07)
CSHL scientists clarify editing error underlying genetic neurodegenerative disease
Two molecular biologists at Cold Spring Harbor Laboratory have uncovered important new details about how a gene mutation causes a cellular editing error that results in a devastating disease called pontocerebellar hypoplasia (PCH). view more (2009-01-29)
Researchers develop new self-training gene prediction program for fungi
Researchers at the Georgia Institute of Technology have developed a computer program that trains itself to predict genes in the DNA sequences of fungi. view more (2008-09-30)
Temperature sensing by the circadian clock
In the September 1 issue of G&D, Dr. Michael Brunner and colleagues have uncovered the molecular mechanism whereby temperature affects circadian patterns in the fungus Neurospora. view more (2005-08-17)
Scientists Find a Fingerprint of Evolution Across the Human Genome
The Human Genome Project revealed that only a small fraction of the 3 billion "letter" DNA code actually instructs cells to manufacture proteins, the workhorses of most life processes. This has raised the question of what the remaining part of the human genome does. How much of the rest performs other biological functions, and how much... view more... (2008-04-09)
The cooperative view: New evidence suggests a symbiogenetic origin for the centrosome
There are two ways in which cooperation is the theme of a paper published this week by Mark Alliegro and Mary Anne Alliegro, scientists at the Marine Biological Laboratory's (MBL) Josephine Bay Paul Center. view more (2008-05-07)
Evolution of fruit size in tomato
Domesticated tomatoes can be up to 1000 times larger than their wild relatives. How did they get so big? In general, domesticated food plants have larger fruits, heads of grain, tubers, etc, because this is one of the characteristics that early hunter-gatherers chose when foraging for food. view more (2008-06-30)
Profile of the Aging Kidney: PLoS Biology Press Release
A Global View of Gene Expression in the Aging Kidney view more (2004-11-23)
Uppsala researchers in Nature: Mutation in non-coding DNA makes pigs more muscular and less fat
Researchers at Uppsala University and the Swedish University for Agricultural Sciences (SLU) report in the latest issue of Nature that they have identified a regulatory mutation in a gene for a known growth factor that makes pigs more muscular and less fat than wild boars. Most characteristics, such as common diseases like diabetes, have a... view more... (2003-10-21)
Scientists find missing evolutionary link using tiny fungus crystal
The crystal structure of a molecule from a primitive fungus has served as a time machine to show researchers more about the evolution of life from the simple to the complex. view more (2008-01-03)
RNA splicing occurs in nerve-cell dendrites
Researchers at the University of Pennsylvania School of Medicine have discovered that nerve-cell dendrites have the capacity to splice messenger RNA (pre-mRNA), a process once believed to only take place in the nucleus of cells. view more (2005-11-08)
Study shows positive findings in treating patients with advanced hepatitis C
The hepatitis C therapy peginterferon alfa-2b, when given as low-dose maintenance therapy, can prevent disease progression in certain patients who failed previous interferon-based hepatitis C therapies and have advanced liver disease, according to findings from a large, four-year study presented today at the 43rd annual meeting of the European... view more... (2008-04-25)
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