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Jefferson scientists discover a key protein regulator of inflammation and cell death
Reporting in the journal Nature, researchers led by Emad Alnemri, Ph.D., professor of Biochemistry and Molecular Biology in the Kimmel Cancer Center at Jefferson, discovered a key protein component involved in inflammation. view more (2009-01-23)
In a crisis, creating DNA vaccine could help save lives, slow spread of 'bird flu'
Researchers scrambling to combat a virulent form of bird flu that could mutate into a form easily spread among humans should consider developing vaccines based on DNA, according to British biochemical engineers. view more (2005-10-20)
Inconsistencies with Neanderthal genomic DNA sequences
Were Neanderthals direct ancestors of contemporary humans or an evolutionary side branch that eventually died out? view more (2007-10-15)
Dartmouth study finds that arsenic inhibits DNA repair
Dartmouth researchers, working with scientists at the University of Arizona and at the Department of Natural Resources in Sonora, Mexico, have published a study on the impact of arsenic exposure on DNA damage. view more (2006-05-30)
UC Davis researchers discover genetic switch involved in cells' response to radiation therapy
UC Davis Cancer Center researchers have discovered a genetic switch that causes cancer cells to become more sensitive to a drug administered to enhance radiation therapy effectiveness. view more (2005-11-17)
SLU Researchers Uncover Direct Evidence on How HIV Invades Healthy Cells
Using sophisticated detection methods, researchers at the Saint Louis University Institute for Molecular Virology (IMV) have demonstrated the molecular mechanism by which the HIV virus infects, or integrates, healthy cells. The discovery could lead to new drug treatments for HIV. view more (2005-12-22)
New nanosensor uses quantum dots to detect DNA
Using tiny semiconductor crystals, biological probes and a laser, Johns Hopkins University engineers have developed a new method of finding specific sequences of DNA by making them light up beneath a microscope. view more (2005-12-06)
Taking aim at mysterious DNA structures in the battle against cancer
Designers of anti-cancer drugs are aiming their arrows at mysterious chunks of the genetic material DNA that may play a key role in preventing the growth and spread of cancer cells, according to an article in the current issue of Chemical & Engineering News, ACS' weekly newsmagazine. view more (2009-11-05)
Seemingly suicidal stunt is normal rite of passage for immune cells
Researchers have shown that self-induced breaks in the DNA of immune cells known as lymphocytes activate genes that cause the cells to travel from where they're made to where they help the body fight invaders. view more (2008-10-21)
Hot Paper in the Biochemical Journal
DNA DAMAGE INSIGHT An exciting new paper from the Biochemical Journal regarding the phosphorylation state of LKB1 in response to ionising radiation can be viewed online as an Immediate Publication at www.BiochemJ.org (DOI: 10.1042/BJ20021284). Researchers at the University of Dundee, the University of Calgary and Tel Aviv University collaborated... view more... (2002-09-20)
DNA Anniversary Poster
2003 is the 50th anniversary of one of the most important breakthroughs in science - the discovery of the DNA double helix by James Watson and Francis Crick in Cambridge in the spring of 1953. A photograph of the pair with their original model of DNA, taken in May 1953 by Antony Barrington Brown, has become an icon of scientific discovery, marking... view more... (2003-02-07)
Baumann Lab demonstrates role of protein in distinguishing chromosome ends from DNA breaks
The Stowers Institute's Baumann Lab has demonstrated how human cells protect chromosome ends from misguided repairs that can lead to cancer. view more (2009-09-18)
Press Briefing - Leading scientists explore the next 50 years of DNA related research
Leading international scientists in the field of molecular biology will be attending a scientific discussion meeting entitled 'Replicating and reshaping DNA: a celebration of the jubilee of the double helix' at the Royal Society on 23rd and 24th April 2003. The meeting will look at the cutting edge of today's science of DNA and how the intricate... view more... (2003-04-16)
Research breakthrough targets genetic diseases
A cure for debilitating genetic diseases such as Huntington's disease, Friedreich's ataxia and Fragile X syndrome is a step closer to reality, thanks to a recent scientific breakthrough. view more (2009-01-21)
Once suspect protein found to promote DNA repair, prevent cancer
An abundant chromosomal protein that binds to damaged DNA prevents cancer development by enhancing DNA repair, researchers at The University of Texas M. D. Anderson Cancer Center report online this week in the Proceedings of the National Academies of Science. view more (2008-07-22)
Single nucleotide polymorphisms and forensic genetics, maybe not such a perfect combination
Forensic genetics is the branch of genetics that, through DNA analysis and comparison, deals with the resolution of legal problems such as paternity tests. Recently, it has been proposed that single nucleotide polymorphisms (SNPs) could be used as a new genetic marker in the field eventually even replacing the methods/markers now employed. But in... view more... (2004-10-21)
Fungi can tell us about the origin of sex chromosomes
Fungi do not have sexes, just so-called mating types. A new study being published today in the prestigious journal PLoS shows that there are great similarities between the parts of DNA that determine the sex of plants and animals and the parts of DNA that determine mating types in certain fungi. view more (2008-03-18)
Just a little squeeze lets proteins assess DNA
To find its target, all a protein needs to do is give quick squeezes as it moves along the DNA strand, suggests new research from The University of Arizona in Tucson. view more (2008-12-17)
Penn researcher shows that DNA gets kinky easily at the nanoscale
Scientists have answered a long-standing molecular stumper regarding DNA: How can parts of such a rigid molecule bend and coil without requiring large amounts of force? view more (2006-11-06)
Cancer cells suppress large regions of DNA by a reversible process that can be tackled
Cancer researchers at Sydney's Garvan Institute, in collaboration with Spanish scientists, have formulated a new concept for how cancer cells can escape normal growth controls, which may have far-reaching implications for the new generation of cancer therapies. view more (2006-04-24)
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