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New study shows how genetic repair mechanism helps seal DNA breaks
As the genetic material, DNA is surprisingly reactive and under continuous assault from environmental toxins and reactive cellular metabolites, so a means of repairing DNA damage is essential to maintaining the integrity of our genetic blueprint for future generations. view more (2006-10-23)
Stressed cells spark DNA repair missteps and speed evolution
When Dr. Susan Rosenberg, professor of molecular and human genetics at Baylor College of Medicine, first published her finding that the mutation rate increased in bacteria stressed by starvation, sometimes resulting in a rare change that benefited the bacteria, it was controversial. view more (2005-09-16)
Links between DNA damage and breast cancer studied
Researchers from the Pacific Northwest Research Institute (PNRI) and the National Institute of Standards and Technology (NIST) have uncovered a pattern of DNA damage in connective tissues in the human breast that could shed light on the early stages of breast cancer and possibly serve as an early warning of a heightened risk of cancer. view more (2006-08-07)
DNA analysis reveals rapid population shift among Pleistocene cave bears
Studying DNA obtained from teeth of ancient cave bears, researchers have been able to identify a shift in a particular population of the bears inhabiting a European valley in the late Pleistocene era. view more (2007-02-20)
New DNA-based technique for assembly of nano- and micro-sized particles
Scientists at the U.S. Department of Energy's Brookhaven National Laboratory have developed a new method for controlling the self-assembly of nanometer and micrometer-sized particles. view more (2007-09-13)
Clemson chemists discover new way antioxidants fight debilitating diseases
Cancer, cardiovascular diseases, Parkinson's and Alzheimer's are often linked to DNA damage that occurs when metal ions in the body such as iron and copper produce reactive oxygen compounds that damage human cells. view more (2007-08-20)
White blood cell uses DNA 'catapult' to fight infection
U.S. and Swiss scientists have made a breakthrough in understanding how a type of white blood cell called the eosinophil may help the body to fight bacterial infections in the digestive tract, according to research published online this week in Nature Medicine. view more (2008-08-14)
iNOS expression may links chronic biliary inflammation to malignant transformation
It is well known that chronic biliary inflammation is a risk factor for biliary carcinogenesis. However, the molecular mechanisms of biliary carcinogenesis as a consequence of chronic biliary inflammation remain unclear. view more (2007-12-20)
Comparing Chimp, Human DNA
Most of the big differences between human and chimpanzee DNA lie in regions that do not code for genes, according to a new study. view more (2006-10-16)
A rainbow of methods promises insights into biological processes and diseases
Physical alterations of DNA in chromosomes can cause serious diseases such as Down syndrome, Prader-Willi syndrome, or cancer. view more (2007-05-02)
Human embryonic stem cells display a unique pattern of chemical modification to DNA
Scientists from the Burnham Institute for Medical Research (BIMR) and Illumina Inc., in collaboration with stem cell researchers around the world, have found that the DNA of human embryonic stem cells is chemically modified in a characteristic, predictable pattern. view more (2006-08-07)
Protein splicing upsets the DNA colinearity paradigm
Understanding medical research problems often relies on the direct, linear relationship between the sequence of a protein and the DNA encoding that protein. view more (2006-09-08)
Firefly's light can help us spot life in space
The luminescent substances of the firefly, luciferase, is used today in various forms of bioanalysis, but it is temperature sensitive. Jonas Eiksson, a doctoral student at the Royal Institute of Technology in Stockholm (KTH), has managed to get the substance to function at higher temperatures, which can yield more certain DNA analyses. In the... view more... (2004-03-05)
Faulty DNA repair could be a risk factor for lung cancer in nonsmokers
People who have never smoked but whose cells cannot efficiently repair environmental insults to DNA are at higher risk of developing lung cancer than those with effective genomic repair capability. view more (2008-06-26)
Ancient DNA confirms single origin of Malagasy primates
Yale biologists have managed to extract and analyze DNA from giant, extinct lemurs, according to a Yale study published in a recent issue of the Proceedings of the National Academy of Sciences. view more (2005-06-07)
New ultrasensitive electronic sensor array speeds up DNA detection
A novel electronic sensor array for more rapid, accurate and cost-efficient testing of DNA for disease diagnosis and biological research has been developed by scientists at Singapore's Institute of Bioengineering and Nanotechnology (IBN). view more (2009-08-27)
Bacteria have their own immune system protecting against outside DNA
Bacteria like Salmonella have a complicated immune system that helps them recognize and isolate foreign DNA trying to invade their cell membrane. view more (2006-06-09)
Raising the alarm when DNA goes bad
Our genome is constantly under attack from things like UV light and toxins, which can damage or even break DNA strands and ultimately lead to cancer and other diseases. view more (2009-08-14)
Jurassic Park inspirer awarded
Professor Svante P'¤'¤bo is the recipient of the Rudbeck Prize year 2000 at Uppsala University, Sweden, in recognition for his pioneering work in unravelling the origin of the modern man. Professor P'¤'¤bo first made world headlines in 1985 when he succeeded in isolating and decoding a short sequence of genetic code (DNA) from an Egyptian mummy... view more... (2000-09-14)
New Company To Develop Next-Generation Sunscreens
SCIENTISTS are using world-first technology to develop the next generation of sunscreens. A new company, DNAcare Systems, is to be formed at the University of Newcastle upon Tyne, based on research by skin cancer expert Dr Mark Birch-Machin and colleagues. It intends to design a new type of sunscreen which will be specially developed for its... view more... (2004-07-07)
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