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Researchers publish first marsupial genome sequence
An international team, led by researchers at the Broad Institute of MIT and Harvard, and supported by the National Institutes of Health (NIH), today announced the publication of the first genome of a marsupial, belonging to a South American species of opossum. view more (2007-05-10)
New gene silencing pathway found in plants
Biologists at Washington University in St. Louis have made major headway in explaining a mechanism by which plant cells silence potentially harmful genes. view more (2008-11-18)
An ancient protein balances gene activity and silences foreign DNA in bacteria
Compared to humans, bacteria have a much tidier genome. The tiny microorganisms pack their genes closely together, and don't carry around a lot of extraneous DNA, so-called junk DNA that fills in the gaps between genes. view more (2008-05-16)
Study of huge numbers of genetic mutations point to oxidative stress as underlying cause
A study that tracked genetic mutations through the human equivalent of about 5,000 years has demonstrated for the first time that oxidative DNA damage is a primary cause of the process of mutation - the fuel for evolution but also a leading cause of aging, cancer and other diseases. view more (2009-09-08)
Important Genetic Research Involving Pseudogenes at Children's Hospital of Pittsburgh Reinforces Theory of Evolution
Scientists led by a Children's Hospital of Pittsburgh geneticist have found new evidence that a category of genes known as pseudogenes serve no function, an important finding that bolsters the theory of evolution. view more (2006-08-02)
Scientists discover small RNAs that regulate gene expression and protect the genome
RNA is best known as a working copy of the DNA sequence of genes. In this role, it's a carrier of the genes' instructions to the cell, which manufactures proteins according to information in the RNA molecule. view more (2008-05-14)
Tiny genetic differences have huge consequences: McGill researchers
A study led by McGill University researchers has demonstrated that small differences between individuals at the DNA level can lead to dramatic differences in the way genes produce proteins. view more (2008-01-21)
Microbe has huge role in ocean life, carbon cycle
Researchers at Oregon State University and Diversa Corporation have discovered that the smallest free-living cell known also has the smallest genome, or genetic structure, of any independent cell-and yet it dominates life in the oceans, thrives where most other cells would die, and plays a huge role in the cycling of carbon on Earth. view more (2005-08-19)
MicroRNA may have fail-safe role in limb development
A tiny strand of molecules plays a role in how our arms and legs develop and grow-a finding that sheds light on perplexing bits of material once dismissed as genetic "junk," say scientists at the University of Florida and Harvard University. view more (2005-12-02)
Common variation in gene linked to structural changes in the brain
An international group of researchers is the first to show that common variations in a gene - previously shown to be associated with Retts Syndrome, autism, and mental retardation - are associated with differences in brain structure in both healthy individuals and patients with neurological and psychiatric disorders. view more (2009-08-18)
Whole genome promoter mapping - Human Genome Project v2.0?
nvestigators from the University California, San Diego (UCSD) Branch of the Ludwig Institute for Cancer Research (LICR) and NimbleGen Systems have developed an efficient method to identify thousands of regulatory sequences in the human genome, according to a study published today in Nature. view more (2005-06-30)
Protein binds whenever it can
Dutch cancer researcher Joost Martens has discovered that the protein p300, which plays an important role in the correct transcription of DNA to RNA, can bind to DNA at several sites. The protein can also occupy a position in various complexes, each with its own protein composition. This knowledge is important for gaining a better understanding of... view more... (2003-06-24)
A better way to copy DNA
Scientists have developed a new method for DNA amplification that could replace the polymerase chain reaction (PCR), a technique that is invaluable for both medical diagnostics and basic research but which is confined to the laboratory. In the August issue of EMBO reports, Huimin Kong and colleagues at New England Biolabs (Beverly, MA, USA)... view more... (2004-07-14)
Few clues about African ancestry to be found in mitochondrial DNA
Mitochondrial DNA may not hold the key to your origins after all. A study published today in the open access journal BMC Biology reveals that fewer than 10% of African American mitochondrial DNA sequences analysed can be matched to mitochondrial DNA from one single African ethnic group. view more (2006-10-12)
Seaweed could make junk food healthier
Junk food could be made healthier by adding an extract of an exotic type of seaweed, say British scientists. view more (2005-09-27)
Evolving complexity out of 'junk DNA'
The study, published today in Proceedings of the National Academy of Sciences, USA, claims to have solved this scientific riddle by analysing the genomics of primitive living fishes such as sharks and lampreys and their spineless relatives, such as the sea squirts. view more (2008-02-12)
Novel mechanism for DNA replication discovered
Since the discovery of the structure of DNA by James Watson and Francis Crick in 1953, the paradigm for DNA replication has stated that the DNA itself codes for the appropriate pairings for replication. view more (2005-09-30)
U of Alberta study discovers how proteins help repair DNA
A person's DNA is often damaged by a number of different chemical contaminants, and if not repaired properly, it can lead to the development of cancer and other diseases. view more (2009-06-16)
Mutating the entire genome
Genes account for only 2.5 percent of DNA in the human genetic blueprint, yet diseases can result not only from mutant genes, but from mutations of other DNA that controls genes. view more (2007-06-18)
Dual enzymatic activity of RECQ1 explained by different quaternary structures
The transient opening of the DNA double helix is a fundamental step in several DNA metabolic processes. This reaction is driven by proteins called helicases, which make use of ATP as fuel to unwind the DNA duplex. view more (2007-01-16)
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