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Tocilizumab study offers new hope for children with arthritis
A new study has confirmed significant improvements after treatment with tocilizumab amongst children with systemic juvenile idiopathic arthritis (sJIA), who do not tolerate or have an inadequate response to conventional therapies.   view more (2006-06-23)

Study provides guidelines for treatment of juvenile idiopathic arthritis
A study published by the Cleveland Clinic and The Hospital for Sick Children (SickKids) provides the medical community for the first time with specific guidelines for treating juvenile idiopathic arthritis (JIA), previously known as juvenile rheumatoid arthritis (JRA), a condition that affects approximately one in every 1,000 children.   view more (2005-10-05)

Pediatric researchers find possible 'master switch' gene in juvenile arthritis
Researchers have found that a gene region known to play a role in some varieties of adult rheumatoid arthritis is also present in all types of childhood arthritis. The researchers say the responsible gene may be a "master switch" that helps turn on the debilitating disease.   view more (2008-07-02)

Childhood arthritis raises risk of broken bones
Childhood arthritis increases the risk of fractures, particularly during adolescence, according to a large study of British patient records.   view more (2006-05-09)

Early life infections increase the risk of rheumatoid arthritis and juvenile idiopathic arthritis
Infections during the first year of life are a marker of increased risk of developing specific types of arthritis later in life.   view more (2008-06-16)

Blood test to predict diabetes in children
The researchers found that four out of five patients with juvenile diabetes have the so-called islet antibodies directed against GAD and IA2 in their blood before the condition manifests itself and that these proteins occur exclusively in cases of juvenile diabetes. The test measures the concentration of the islet antibodies in the child's blood.... view more... (2000-01-18)

3 studies confirm the value of etanercept therapy in treating juvenile idiopathic arthritis
Three new studies have individually shown the anti-TNF (tumour necrosis factor) therapy etanercept to be effective, with a good safety profile, in children under four years of age with juvenile idiopathic arthritis (JIA).   view more (2009-06-12)

Identification of role for proteins in children's muscle disease could open up new treatment options
A study presented by Mrs. Elisabeth Elst today shows for the first time that a protein—heat shock protein 60 (HSP60) — that is present in chronic inflammations, triggers a response by T-cells (a type of white blood cells that plays a part in the body's own immune response) in children with juvenile dermatomyositis (JDM).   view more (2006-06-22)

Genes are of little importance in rheumatoid arthritis
Genes are of little importance in the development of rheumatoid arthritis, finds a study in this week's BMJ.   view more (2002-01-30)

Subclinical markers predict relapse in juvenile idiopathic arthritis post methotrexate withdrawal
Elevated levels of the inflammatory biomarkers Myeloid Related Protein (MRP) 8/14 predict an increased risk of relapse following withdrawal of methotrexate (MTX) therapy in children with juvenile idiopathic arthritis (JIA) who have achieved inactive disease status.   view more (2009-06-11)

Methotrexate treatment for rheumatoid arthritis effective the second time
A second course of methotrexate, the most commonly used drug to treat rheumatoid arthritis, is effective in nearly half of studied patients for whom a previous treatment with the drug was ineffective.   view more (2006-02-24)

Early treatment of systemic onset JIA with anakinra restores the IL-18 response
First line treatment with anakinra (an interleukin-1 (IL-1) receptor antagonist), results in a 'good' clinical response (ACRp90) in patients newly diagnosed with systemic onset juvenile idiopathic arthritis (SoJIA), and restores the deficient IL-18 response of natural killer (NK) cells.   view more (2009-06-15)

Women who breastfeed for more than a year halve their risk of rheumatoid arthritis
Women who breast feed for longer have a smaller chance of getting rheumatoid arthritis, suggests a study published online ahead of print in the Annals of the Rheumatic Diseases.   view more (2008-05-13)

Inflammatory bowel disease is a risk factor for thrombosis
People with inflammatory bowel disease (IBD) are more than three times as likely to develop blood clots in their veins (venous thromboembolism), finds new research in Gut. Thromboembolism is a serious and potentially life threatening event. For many years, patients with IBD were thought to be at increased risk, but the evidence has been... view more... (2004-03-09)

Abnormal immune cells may cause unprovoked anaphylaxis
Two new clinical reports shed light on why some people suffer from recurrent episodes of idiopathic anaphylaxis--a potentially life-threatening condition of unknown cause characterized by a drop in blood pressure, fainting episodes, difficulty in breathing, and wheezing.   view more (2007-11-12)

Gene expression findings a step toward better classification and treatment of juvenile arthritis
Scientists have discovered gene expression differences that could lead to better ways to classify, predict outcome, and treat juvenile idiopathic arthritis (JIA).   view more (2009-06-30)

Women with rheumatoid arthritis have significantly less chance of remission than men
Women with rheumatoid arthritis have significantly less chance of remission than men, finds research published ahead of print in the Annals of the Rheumatic Diseases.   view more (2006-12-07)

New study finds 'delinquent behavior among boys contagious'
Impulsive boys with inadequate supervision, poor families and deviant friends are more likely to commit criminal acts that land them in juvenile court, according to a new study published in the Journal of Child Psychology and Psychiatry.   view more (2009-07-17)

Coffee may be linked to rheumatoid arthritis
Coffee drinkers seem to be at increased risk of developing rheumatoid arthritis, suggests research in the Annals of the Rheumatic Diseases. The association between coffee drinking and the presence of a hallmark indicator for the development of rheumatoid arthritis?rheumatoid factor?was studied in a cross sectional survey of almost 7,000 people,... view more... (2000-07-24)

Media invitation - PARE Manifesto International Media Briefing at EULAR 2004
At EULAR 2004, the 5th Annual European Congress of Rheumatology, in Berlin, Germany Friday 11th June 2004, 10.30am-11.30am - Breakfast provided Room 11/12, International Congress Centre ICC Berlin, Messedamm 22, D-14055 Berlin, Germany The People with Arthritis / Rheumatism in Europe (PARE) Manifesto Steering Group invites you to be among the... view more... (2004-05-07)
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