Keratinocytes Current Events | Keratinocytes News
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Research Suggests New Options in Treating Skin Pigment Problems
Melanocytes are not the only cells responsible for differences in skin coloration. New research from the University of Cincinnati (UC) has shown that some of the most basic cells on the skin's surface influence pigment production and help regulate skin coloration. view more (2007-08-23)
Possible New Cure for Psoriasis
Cell biologists of the University of Bonn, in cooperation with the University of Leeds (U.K.) and industry may have discovered a new effective therapy for psoriasis: a specific group of what are known as metalloproteinase inhibitors can normalise the increased tendency of epidermis cells (keratinocytes) to divide, which is the cause of this... view more... (2004-08-16)
Natural compound in broccoli could treat devastating genetic skin disorder
The compound sulforaphane whose natural precursors are found at high levels in broccoli and other cruciferous vegetables has been hailed for its chemopreventive powers against cancer. view more (2007-12-03)
'Guardian of the genome' protein found to underlie skin tanning
A protein known as the "master watchman of the genome" for its ability to guard against cancer-causing DNA damage has been found to provide an entirely different level of cancer protection: By prompting the skin to tan in response to ultraviolet light from the sun, it deters the development of melanoma skin cancer, the fastest-increasing... view more... (2007-03-09)
First reconstitution of an epidermis from human embryonic stem cells
Stem cell research is making great strides. This is yet again illustrated by a study carried out by the I-STEM* Institute (I-STEM/ Inserm UEVE U861/AFM), published in the Lancet on 21 November 2009. The I-STEM team, directed by Marc Peschanski has just succeeded in recreating a whole epidermis from human embryonic stem cells. view more (2009-11-20)
Gene involved in common birth defect also regulates skin biology
Following up on an earlier discovery that a gene called IRF6 is involved in the common birth defect cleft lip and palate. view more (2006-10-16)
Surface bacteria maintain skin's healthy balance
On the skin's surface, bacteria are abundant, diverse and constant, but inflammation is undesirable. Research at the University of California, San Diego School of Medicine now shows that the normal bacteria living on the skin surface trigger a pathway that prevents excessive inflammation after injury. view more (2009-11-23)
Small molecules may explain psoriasis
A research team at the Swedish medical university Karolinska Institutet has shown for the time that microRNA, small RNA molecules, may play an important role in the development of inflammatory skin diseases such as psoriasis and atopic eczema. view more (2007-07-12)
UAB researchers report breakthrough in HPV research
UAB (University of Alabama at Birmingham) researchers have developed a new, inexpensive and efficient method for producing and studying a type of human papillomavirus (HPV) that causes cervical cancer. The process could speed understanding of how the virus functions and causes diseases, and lead to new prevention or treatment options. view more (2009-02-24)
Genetic breakdown in Fanconi anemia may have link to HPV-associated cancer
A genetic malfunction that causes DNA instability in people with the blood disorder Fanconi anemia may put them at high risk for squamous cell carcinomas linked to human papillomavirus (HPV), according to a study posted online ahead of print by Oncogene. view more (2008-12-04)
New insight into skin-tanning process suggests novel way of preventing skin cancer
Findings from a study led by researchers at Dana-Farber Cancer Institute and Children's Hospital Boston have rewritten science's understanding of the process of skin tanning - an insight that has enabled them to develop a promising way of protecting fair-skinned people from skin cancer caused by exposure to sunlight. view more (2006-09-21)
Hair-raising stem cells identified
Using an animal model, a research team led by Yann Barrandon at the EPFL (Ecole Polytechnique Federale de Lausanne) and the CHUV (Lausanne University Hospital) has discovered that certain cells inside the hair follicle are true multipotent stem cells, capable of developing into the many different cell types needed for hair growth and follicle... view more... (2005-10-05)
Caspase-14 protects our skin against UVB and dehydration
Ultraviolet rays can be harmful to our skin and pave the way to the onset of skin cancers. VIB researchers connected to Ghent University have demonstrated that the caspase-14 protein - whose function has been unknown up to now - not only plays a role in maintaining the balance of moisture in the skin but also offers protection against UVB rays. view more (2007-05-22)
Expression of 'Blimp1' gene leads to the discovery of cells responsible for skin's sebaceous gland
Mice may not get zits, but they do have oily skin. This week, new research on mice from Rockefeller University shows how the cells responsible for oil production develop, and uncovers clues about how stem cells renew and differentiate. view more (2006-08-11)
Genetically altered cells may help artificial skin fight infection
Cincinnati burn researchers have created genetically modified skin cells that, when added to cultured skin substitutes, may help fight off potentially lethal infections in patients with severe burns. view more (2007-01-09)
Protein protects anti-cancer gene from chemical shutdown
A protein that is largely absent in one type of skin cancer protects an important gene in a cell's defense against harmful mutations from being silenced. view more (2007-07-20)
Function of key protein in Alzheimer's discovered
Scientists at the University of Bonn, working in collaboration with Italian researchers, have discovered the biological function of a protein normally associated with the onset of the Alzheimer's disease. Their results were published at the end of September in the US periodical "FASEB Journal", and the full-length report is already... view more... (2003-08-21)
Research could lead to new treatments for birth defects
Pioneering new research into cleft lip and palate could open the door to babies with certain craniofacial disorders being successfully treated in the womb. view more (2006-10-16)
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