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Kidney Tumor Current Events | Kidney Tumor News | 11

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Researchers identify new drug targets for cancer
Solving a 100-year-old genetic puzzle, researchers at the University of California, San Diego (UCSD) School of Medicine have determined that the same genetic mechanism that drives tumor growth can also act as a tumor suppressor.   view more (2007-01-02)

USC researchers discover breast cancer stem cells in bone marrow
Almost all tumor cells found in the bone marrow of early stage breast cancer patients appear to be breast cancer stem cells, suggesting the risk of disease spread for all breast cancer patients may be greater than previously thought.   view more (2006-10-09)

Experiments point to new treatments for PKD
A family of small molecules called CFTR inhibitors show promising effects in slowing the progression of polycystic kidney disease (PKD), the most common genetic disease of the kidneys, according to preliminary research reported in the July 2008 issue of the Journal of the American Society Nephrology.   view more (2008-04-03)

Lowering your cholesterol may decrease your risk of cancer
Current research suggests that lowering cholesterol may block the growth of prostate tumors. The related report by Solomon et al, "Ezetimibe Is an Inhibitor of Tumor Angiogenesis," appears in the March 2009 issue of The American Journal of Pathology.   view more (2009-02-24)

Polycystic kidney disease: MRI provides an early alert to progression
A new method using magnetic resonance imaging (MRI) accurately tracks structural changes that predict functional changes earlier than standard blood and urine tests in people with autosomal dominant polycystic kidney disease (PKD).   view more (2006-05-18)

USC researchers develop new drug to target tumor cells and blood vessels
Researchers at the University of Southern California have identified a new drug compound that appears to target tumor cells and surrounding blood vessels without the negative side effects typically associated with Cox-2 inhibitors.   view more (2009-04-20)

Barrow researchers identify a new approach to detect the early progression of brain tumors
Researchers at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center recently participated in a pilot study with the Montreal Neurological Institute that suggests a certain type of MRI scanning can detect when a patient is failing brain tumor treatment before symptoms appear.   view more (2008-08-29)

SIRT1 takes down tumors
Yuan et al. have identified another anti-cancer effect of the "longevity" protein SIRT1. By speeding the destruction of the tumor promoter c-Myc, SIRT1 curbs cell division.   view more (2009-04-13)

Study links gastric bypass surgery to increased risk of kidney stones
Morbidly obese patients who undergo a particular type of gastric bypass surgery called Roux-en-Y gastric bypass (RYGB) are at an increased risk of developing kidney stones - small, pebble-like deposits that can result in severe pain and require an operation to remove them - earlier than previously thought.   view more (2008-06-26)

Existing drugs show promise for treating end-stage renal disease in lupus
Studies in mice suggest that two drugs already approved by the U.S. Food and Drug Administration show promise for treating the complications of lupus.   view more (2007-11-12)

Impaired kidney function raises risk of heart problems in the elderly
A study published next week in the open access journal PLoS Medicine suggests that elderly people with damaged kidneys are at greater risk of cardiovascular disease, such as heart failure and stroke, and other causes of mortality.   view more (2009-01-21)

Creatinine Increase in Elderly Means Increased Renal Disease, Mortality
Even small increases in serum creatinine levels during hospitalization raise the risk of end stage renal disease and mortality of elderly patients over the long term, according to a University of Alabama at Birmingham (UAB) study in the March issue of the Archives of Internal Medicine.   view more (2008-04-16)

2 heads are better than 1: 2 dysfunctional DNA repair pathways kill tumor cells
Individuals who inherit two mutant copies of any one of about 12 genes that make the proteins of the Fanconi Anemia (FA) pathway develop FA, which is characterized by increased incidence of cancer and bone marrow failure, among other things.   view more (2007-04-13)

USC researchers show that molecular markers predict tumor recurrence
Researchers at the University of Southern California (USC) have identified specific molecular markers that may help to predict tumor recurrence in stage II and III colon cancer patients.   view more (2007-06-06)

Mayo collaboration identifies gene in childhood kidney disease
An international research collaboration led by Mayo Clinic has identified a new gene involved in causing the inherited kidney disorder, Meckel-Gruber syndrome (MKS).   view more (2006-01-16)

Metabolic syndrome heightens risk for development of uric-acid kidney stones
Researchers at UT Southwestern Medical Center have found that patients suffering from the metabolic syndrome - a cluster of conditions that increases the risk for heart disease, stroke and diabetes - also have a propensity to develop highly acidic urine, which increases the risk of developing kidney stones.   view more (2007-09-13)

Milestone tumor virus publication by Elsevier journal Virology
A recent special edition of the Elsevier journal Virology reviews the past, present, and future of the exciting field of small DNA tumor viruses.   view more (2009-04-10)

Experimental anti-cancer synthetic molecule targets tumor cell growth and angiogenesis
A recent study conducted by three French CNRS (Centre National de la Recherche Scientifique) laboratories describes a new candidate anti-cancer drug, named HB-19.   view more (2008-06-18)

Stem cell protein offers a new cancer target
A protein abundant in embryonic stem cells is now shown to be important in cancer, and offers a possible new target for drug development, report researchers from the Stem Cell Program at Children's Hospital Boston.   view more (2009-06-02)

Promising advance in breast cancer research
Two new drugs, when combined, killed up to 75 percent of breast cancer tumor cells in mice and suppressed the regrowth of tumors, according to researchers at the Virginia Commonwealth University Massey Cancer Center.   view more (2005-11-15)
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