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New insight in the fight against the Leishmania parasite
Professor Albert Descoteaux's team at Centre INRS - Institut Armand-Frappier has gained a better understanding of how the Leishmania donovani parasite manages to outsmart the human immune system and proliferate with impunity, causing visceral leishmaniasis, a chronic infection that is potentially fatal if left untreated.   view more (2009-10-26)

A new antibiotic improves treatment of parasitic infections
A team of researchers from the Universitat Autònoma de Barcelona, lead by Professor Jordi Alberola, has demonstrated the efficacy and safety of a new type of antibiotic, belonging to the family called antimicrobial peptides, for treating canine leishmaniasis, which is a disease that also affects humans. It is the first time that these... view more... (2004-02-13)

UIC researchers hunting drugs for devastating parasitic disease
Hundreds of millions of people, mainly in developing countries, are disabled by infectious diseases, according to the World Health Organization.   view more (2008-12-17)

Potential vaccine developed for deadly leishmaniasis disease
Development of a fundamentally new "candidate," or potential, vaccine for visceral leishmaniasis (LEASH-ma-NIGH-a-sis), a parasitic disease that kills about 60,000 people annually, is reported in the current issue of ACS Chemical Biology.   view more (2006-04-24)

Improved diagnosis of cutaneous leishmaniasis thanks to new techniques
Dutch researcher Wendy van der Meide has developed and evaluated new techniques for a better diagnosis of cutaneous leishmaniasis and an improved monitoring of its treatment. Accurately establishing the number of parasites in a skin lesion before, during and after treatment is vital, so as to prevent serious physical consequences.   view more (2008-01-25)

Dermatologists identify North Texas leishmaniasis outbreak
A team of dermatologists and dermatopathologists at UT Southwestern Medical Center has identified nine North Texas cases of an infectious skin disease common in South America, Mexico and in the Middle East, where it is sometimes referred to as a "Baghdad boil."   view more (2007-09-14)

Leishmaniasis parasites evade death by exploiting the immune response to sand fly bites
Cutaneous leishmaniasis, a disease characterized by painful skin ulcers, occurs when the parasite Leishmania major, or a related species, is transmitted to a mammalian host by the bite of an infected sand fly.   view more (2008-08-15)

Pitt, US Army team designs new strategy to find drugs to treat neglected infection
Using an unconventional approach that they designed, University of Pittsburgh drug discoverers and their collaborators at Walter Reed Army Institute of Research have identified compounds that hold promise for treating leishmaniasis, a parasitic infection that many consider one of the world's most overlooked diseases.   view more (2009-11-03)

Dog Collars Could Prevent Parasitic Disease In Children
Children could be protected from a potentially lethal parasitic disease if dogs were fitted with insecticide-impregnated collars, suggest authors of a study in THE LANCET this week. Zoonotic visceral leishmaniasis is caused by transmission of a parasite, Leishmania infantum, from animals (mostly domestic dogs) by blood-sucking sandflies. In... view more... (2002-07-31)

New research team to tackle disease
A new Immunology and Infection Unit, which will research how disease occurs and how our immune systems respond, opens shortly in York. The Unit is a joint venture of the Department of Biology at York and the Hull York Medical School (HYMS). Professor Paul Kaye, who joins the University of York from the London School of Hygiene and Tropical... view more... (2004-03-15)

Potent possibilities for parasite attack
A comparison of three parasite species that cause Leishmaniasis has identified a small number of genes, many new to biology, that will provide a framework to target the search for new treatments.   view more (2007-06-18)

Cure for Fatal Tropical Disease - Oral Treatment of Leishmaniasis
Leishmaniasis is one of several names for various tropical diseases, which are caused by flagellates of the genus Leishmania. The parasites are transmitted by sandflies, blood-sucking insects of the tropical and subtropical zones. The manifestation of the disease may be visceral (kala-azar), mucocutaneous (American Leishmaniasis) or cutaneous... view more... (2000-02-22)

How much is the world spending on neglected disease research and development?
The first comprehensive survey of global spending on neglected disease R&D, published in this week's PLoS Medicine, finds that just over $US 2.5 billion was invested into R&D of new products in 2007, with three diseases-HIV/AIDS, TB, and malaria-receiving nearly 80% of the total.   view more (2009-02-04)

Deadly parasite's rare sexual dalliances may help scientists neutralize it
For years, microbiologist Stephen Beverley, Ph.D., has tried to get the disease-causing parasite Leishmania in the mood for love.   view more (2009-04-10)

New role for Natural Killers!
Scientists at the University of York have discovered a new role for a population of white blood cells, which may lead to improved treatments for chronic infections and cancer.   view more (2008-08-28)

It`s good to talk: new multidiciplinary journal aims to improve communication between researchers
Although there has been an intensive research effort focused on diseases caused by kinetoplastid parasites, there has been little success in developing effective ways of treating them. The launch of the online journal Kinetoplastid Biology and Disease represents the practical first step in tackling some of the communication difficulties that face... view more... (2002-08-19)

New highly active agents against leishmaniasis
Parasitic diseases, especially leishmaniases and trypanosomiases, kill hundreds of thousands of people every year in the world, mainly in the countries of the South. The most severe form of leishmaniosis (kala-azar, the visceral form), induced by Leishmania donovani and L. infantum, affects about 500 000 people per year and proves fatal if no... view more... (2005-01-25)

Neglected tropical diseases burden those overseas, but travelers also at risk
Though little known to most Americans, lymphatic filariasis, trachoma, leishmaniasis, onchocerciasis, schistosomiasis and other so-called neglected tropical diseases are responsible for severe health burdens, especially among the world's poorest people.   view more (2007-12-26)

Bioprospecting not biopiracy
By training professionals in high-biodiversity regions to advance the drug discovery process in-country, a novel program drives drug discovery costs down as it promotes tropical biodiversity conservation.   view more (2006-12-08)

Don't blame the trees: Social factors, not forests, dictate disease patterns
A new study published February 6 in the open access journal PLoS Neglected Tropical Diseases suggests that socioeconomic factors best explain patterns of the infectious disease American Cutaneous Leishmaniasis (ACL) in Costa Rica.   view more (2008-02-06)
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