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Cardiac stent patients with diabetes may benefit from drug that counteracts the effects of leptin
The naturally high levels of leptin in diabetic patients may reduce the effectiveness of drug-eluting stents used to treat heart blockages, but using a chemical that differs from the one commonly used to coat stents could counteract this effect. view more (2008-12-18)
Research provides clues to obesity's cause and hints of new approach for curbing appetite
Hot fudge sundaes and french fries aside, new research suggests obesity is due at least in part to an attraction between leptin, the hormone that signals the brain when to stop eating, and a protein more recently associated with heart disease. view more (2006-04-10)
Scientists find obesity alone does not cause arthritis in animals
The link between obesity and osteoarthritis may be more than just the wear and tear on the skeleton caused by added weight. view more (2009-09-29)
Bad news for insomniacs: 'hunger hormones' affected by poor sleep
Insomnia has long been associated with poor health, including weight gain and even obesity. Now researchers at UCLA have found out why. view more (2009-03-26)
Weight control protein may yield antiobesity drugs
A weight control protein with a key role in the brain's ability to monitor body fat content may yield new approaches for treating obesity and type 2 diabetes, according to a new report in the August issue of Cell Metabolism. view more (2005-08-17)
Leptin found to control appetite and limb development in frogs
Leptin, the hormone secreted by fat cells that plays an important role in food intake, has been described for the first time in a cold-blooded vertebrate, the South African clawed frog Xenopus. view more (2006-06-13)
High risk of breast cancer associated with genetic variation in leptin and its receptor
Individuals with either of two genetic variations that lead to high serum levels of the cytokine leptin and to overexpression of leptin in fatty tissue, are more at risk of developing breast cancer than others. view more (2006-02-21)
Obesity: Reviving the promise of leptin
The discovery more than a decade ago of leptin, an appetite-suppressing hormone secreted by fat tissue, generated headlines and great hopes for an effective treatment for obesity. view more (2009-01-07)
Rare syndrome provides clues on obesity, blood pressure
University of Iowa researchers have found a clue about how resistance to the hormone leptin might disrupt the brain signals that tell the body when to stop eating. view more (2008-03-04)
Study shows direct link between leptin and obesity-related cardiovascular disease
Obese people who don't have high cholesterol or diabetes might think they're healthy - despite the extra pounds. view more (2008-11-11)
Does the lack of sleep make you fat?
The recent rise in obesity may be partly due to the reduced amount of time we spend asleep, according to new research from the University of Bristol, UK. view more (2004-12-06)
Ob1, the first commmon obesity gene was located on chromosome 10
Each family has at least one member whose body mass index (BMI, the ratio of the weight in kg to the surface of the body in m2; normal BMI is below 25) is higher than 40 and at least one other member whose BMI is over 27. 380 genetic markers, covering 23 pairs of chromosomes, were studied in order to find genetic similarities between the obese... view more... (1998-11-16)
Scarring key to link between obesity and diabetes
The team, in collaboration with University Hospital Aintree, the University of Warwick and researchers in Sweden, found that people classified as obese and those with pre-diabetes have raised levels of a protein called SPARC, that can cause tissue scarring. view more (2009-08-14)
University of Florida study shows leptin could combat type 2 diabetes
University of Florida researchers have discovered the appetite-controlling hormone leptin could also combat type 2 diabetes, a disease that has become a growing problem in the United States as more Americans pack on extra pounds. view more (2006-09-21)
MSU researchers make new discoveries on what does and doesn't affect immune system
Scientists know that a number of factors can affect the body's immune system: poor diet, certain steroids, chronic stress. Now researchers at Michigan State University have discovered that an appetite-controlling hormone also affects the immune system, while natural versions of certain steroids do not. view more (2008-02-05)
Study further expands understanding of leptin's role in brain neurocircuitry
In investigating the complex neurocircuitry behind weight gain and glucose control, scientists have known that the hormone leptin plays a key role in the process. view more (2009-06-03)
How does soy promote weight loss? University of Illinois scientist finds another clue
Research shows that when soy consumption goes up, weight goes down. A new University of Illinois study may help scientists understand exactly how that weight loss happens. view more (2007-05-02)
Hormone regulates fondness for food
Scientists have discovered that leptin, one of the key hormones responsible for reducing hunger and increasing the feeling of fullness, also controls our fondness for food. view more (2007-08-10)
U of I study shows benefits of hormone found in fat tissue
It's called the obesity paradox. Although obese people are more apt to suffer from inflammatory diseases, such as diabetes, heart disease, and stroke, they are also more likely to survive a major attack caused by one of those conditions. view more (2009-02-27)
Scientists discover leptin can also aid type 1 diabetics
Terminally ill rodents with type 1 diabetes have been restored to full health with a single injection of a substance other than insulin by scientists at UT Southwestern Medical Center. view more (2008-08-26)
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