Leukemia Current Events | Leukemia News | 5
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Data suggesting that omacetaxine can eradicate leukemic stem cells may offer a breakthrough for CML
Data showing the ability of omacetaxine to kill leukemic stem cells in mouse models with drug-resistant chronic myelogenous leukemia (CML) are the subject of an advance online publication in the journal Leukemia, ChemGenex Pharmaceuticals Limited (ASX:CXS and NASDAQ:CXSP) announced today. view more (2009-03-27)
Data suggesting that omacetaxine can eradicate leukemic stem cells may offer a breakthrough for CML
Data showing the ability of omacetaxine to kill leukemic stem cells in mouse models with drug-resistant chronic myelogenous leukemia (CML) are the subject of an advance online publication in the journal Leukemia, ChemGenex Pharmaceuticals Limited (ASX:CXS and NASDAQ:CXSP) announced today. view more (2009-03-26)
Study finds heart failure is rare among leukemia patients on imatinib
Congestive heart failure rarely occurs among leukemia patients who take imatinib, researchers at The University of Texas M. D. Anderson Cancer Center found after an exhaustive review of the detailed medical histories of 1,276 patients who enrolled in clinical trials for the drug. view more (2007-09-07)
First use of antibody and stem cell transplantation to successfully treat advanced leukemia
For the first time, researchers at Fred Hutchinson Cancer Research Center have reported the use of a radiolabeled antibody to deliver targeted doses of radiation, followed by a stem cell transplant, to successfully treat a group of leukemia and pre-leukemia patients for whom there previously had been no other curative treatment options. view more (2009-11-06)
St. Jude identifies genomic causes of a certain type of leukemia relapse
Scientists at St. Jude Children's Research Hospital have identified distinctive genetic changes in the cancer cells of children with acute lymphoblastic leukemia (ALL) that cause relapse. The finding offers a pathway to designing treatments for ALL relapse in children and, ultimately, in adults. view more (2008-12-01)
Comprehensive look at rare leukemia finds relatively few genetic changes launch disease
The most comprehensive analysis yet of the genome of childhood acute myeloid leukemia (AML) found only a few mistakes in the genetic blueprint, suggesting the cancer arises from just a handful of missteps. view more (2009-07-28)
A Broken Stress Response System Can Contribute to Gleevec Resistance
New clues to why some kinds of leukemia are more aggressive and deadly than others are coming from research examining the types of genetic damage that allow some blood cells to grow out of control, scientists report. view more (2006-04-21)
First antisense drug provides benefit to subset of chronic lymphocytic leukemia patients
The first "antisense" drug to be tested in chronic lymphocytic leukemia (CLL) shows benefit in a phase III clinical trial for a specific subset of patients-those who are still sensitive to a chemotherapy drug often used to treat this cancer. view more (2007-02-15)
How cells change gears: New insights published in Nature Genetics
Bioinformatics researchers from UC San Diego just moved closer to unlocking the mystery of how human cells switch from "proliferation mode" to "specialization mode." This computational biology work from the Jacobs School of Engineering's bioengineering department could lead to new ideas for curbing unwanted cell... view more... (2009-04-21)
Dismissed leukemia drug helps cll patients, studies show
A drug once dismissed as ineffective in patients with chronic lymphocytic leukemia (CLL) has shown promising results in two phase I and II clinical trials, according to researchers at The Ohio State University Comprehensive Cancer Center - James Cancer Hospital and Solove Research Institute. view more (2008-12-08)
St. Jude finds factors that accelerate resistance to targeted therapy in lymphoblastic leukemia
Results of a study by investigators at St. Jude Children's Research Hospital provide strong evidence for why the targeted therapy drug imatinib (Gleevec™), which has revolutionized the treatment of chronic myelogenous leukemia (CML), is often unable to prevent relapse of a particularly aggressive form of acute lymphoblastic leukemia (ALL). view more (2007-08-30)
Rare immune cell is key to transplant's cancer-killing effect
Researchers at the University of Michigan's Comprehensive Cancer Center have discovered the secret weapon behind the most powerful form of cancer immunotherapy known to medicine. view more (2005-10-17)
University of Pittsburgh discovers genetic 'shut down' trigger in healthy immune cells
A fundamental genetic mechanism that shuts down an important gene in healthy immune system cells has been discovered that could one day lead to new therapies against infections, leukemia and other cancers. view more (2007-05-10)
Discovery in 'Bubble Boy' disease gene therapy
Scientists at St. Jude Children's Research Hospital have developed a mouse model of a severe disease of the immune system that helps explain why gene therapy used to treat children with this disease at an institution in Europe caused some of them to develop leukemia. view more (2006-08-02)
Leukemia drug proves safe and effective over the long term
The drug imatinib mesylate, more commonly known as Gleevec, proves safe and effective over the long term in patients with an advanced form of chronic myeloid leukemia (CML), according to a study prepublished online in Blood, the official journal of the American Society of Hematology. view more (2007-11-08)
Tree rings show elevated tungsten coincides with Nevada leukemia cluster
Tungsten began increasing in trees in Fallon, Nev. several years before the town's rise in childhood leukemia cases, according to a new research report. view more (2007-05-01)
Inherited risk factors increase odds of developing childhood acute lymphoblastic leukemia
Scientists at St. Jude Children's Research Hospital have identified inherited variations in two genes that account for 37 percent of childhood acute lymphoblastic leukemia (ALL), including a gene that may help predict drug response. view more (2009-08-17)
St. Jude discovery offers new avenues to understanding an aggressive form of leukemia
Researchers at St. Jude Childrenˇ¦s Research Hospital have discovered evidence that a series of genetic mutations work together to initiate most cases of an aggressive and often-fatal form of acute lymphoblastic leukemia (ALL). view more (2008-04-15)
Massey researchers induce cell death in leukemia
Researchers from the Virginia Commonwealth University Massey Cancer Center today presented preclinical research at the American Association of Cancer Research's annual meeting suggesting the potential of a new combination treatment for chronic lymphocytic leukemia (CLL). view more (2007-04-17)
Scientists discover new role for miRNA in leukemia
Scientists here have found that mini-molecules called micro-RNA may play a critical role in the progression of chronic myeloid leukemia (CML) from its more treatable chronic phase to a life-threatening phase, called blast crisis. view more (2007-12-10)
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