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Dasatinib, Nilotinib show strong early results as frontline therapy for chronic myelogenous leukemia
Two drugs approved for use as second line therapy for chronic myelogenous leukemia are showing promising results as frontline therapy for newly diagnosed patients in two clinical trials, research teams led by scientists at The University of Texas M. D. Anderson Cancer Center report at the 49th annual meeting of the American Society of Hematology.   view more (2007-12-10)

Scientists: New technique identifies molecular 'biomarkers' for disease
University of Florida chemists are the first to use a new tool to identify the molecular signatures of serious diseases -- without any previous knowledge of what these microscopic signatures or "biomarkers" should look like.   view more (2008-04-01)

UCLA researchers find blood stem cells originate and are nurtured in the placenta
Solving a long-standing biological mystery, UCLA stem cell researchers have discovered that blood stem cells, the cells that later differentiate into all the cells in the blood supply, originate and are nurtured in the placenta.   view more (2008-03-06)

Leukemia drug proves safe and effective over the long term
The drug imatinib mesylate, more commonly known as Gleevec, proves safe and effective over the long term in patients with an advanced form of chronic myeloid leukemia (CML), according to a study prepublished online in Blood, the official journal of the American Society of Hematology.   view more (2007-11-08)

Tree rings show elevated tungsten coincides with Nevada leukemia cluster
Tungsten began increasing in trees in Fallon, Nev. several years before the town's rise in childhood leukemia cases, according to a new research report.   view more (2007-05-01)

Addition of dasatinib to standard chemo cocktail may enhance effect in certain ovarian cancers
The addition of a chemotherapeutic drug for leukemia to a standard regimen of two other chemotherapy drugs appears to enhance the response of certain ovarian cancers to treatment, according to a pre-clinical study led by researchers in the Duke Comprehensive Cancer Center.   view more (2009-04-20)

Study by NTU professors provides important insight into apoptosis or programmed cell death
A study by Nanyang Technological University (NTU)'s Assistant Professor Li Hoi Yeung, Assistant Professor Koh Cheng Gee and their team have made an important contribution to the understanding of the process that cells go through when they die.   view more (2009-07-14)

UC Davis researchers report new molecule that targets leukemia and lymphoma cells
UC Davis Cancer Center researchers have developed a novel peptide that binds to the surface of leukemia and lymphoma cells with extremely high affinity, specificity and stability, and demonstrates remarkable promise as a tool to help image tumors and deliver anti-cancer drugs.   view more (2006-06-13)

Early Phase II results show bosutinib safe, effective for CML
A new drug for chronic myelogenous leukemia works for patients who have developed resistance to frontline therapy and causes fewer side effects than other medications in its class, a research team led by scientists at The University of Texas M. D. Anderson Cancer Center reports at the 49th annual meeting of the American Society of Hematology.   view more (2007-12-11)

U of M begins nation's first clinical trial using T-reg cells from cord blood in leukemia treatment
University of Minnesota researchers have initiated a ground breaking clinical trial to determine the optimal dose and safety of T regulatory cells (T-regs) to decrease the risk of immune reactions common in patients undergoing blood and marrow transplantation.   view more (2007-09-06)

Molecular science could further improve leukemia survival, say St. Jude researchers
The dramatic increase that has occurred in the cure rate for children with acute lymphoblastic leukemia (ALL) will be difficult to replicate in older patients without considerable additional research.   view more (2008-03-24)

Nilotinib appears to help chronic myelogenous leukemia patients when standard care fails
The targeted agent nilotinib (AMN107) appears to offer striking benefits in patients with chronic myelogenous leukemia (CML) who are resistant to Gleevec, the standard therapy for this cancer.   view more (2006-06-15)

Shilatifard Lab Identifies New Role for Factor Critical to Transcription
The Stowers Institute's Shilatifard Lab has identified a new role for the elongation factor ELL in gene transcription by RNA polymerase II (Pol II) - the enzyme that synthesizes messenger RNA to carry genetic information from DNA to the protein-synthesizing machinery of the cell.    view more (2008-06-18)

Is there a risk of transmitting genetic disorders to babies conceived by fertility procedures?
As medical technology continues to advance, fertility procedures such as in-vitro fertilization and donor insemination are becoming more commonplace.   view more (2006-05-22)

Chemosensitivity of cancer cells depends on their protein dependency
Two different anti-apoptotic proteins support cancer cell survival via an identical mechanism, yet differ in their sensitivity to chemotherapeutic drugs, report Brunelle et al. The study will be published online October 26, 2009 and in the November 2, 2009 print issue of the Journal of Cell Biology (JCB).   view more (2009-10-26)

UAB Researchers Discover Antibody Receptor Identity, Propose Renaming Immune-System Gene
Researchers at the University of Alabama at Birmingham (UAB) have uncovered the genetic identity of a cellular receptor for the immune system's first-response antibody, a discovery that sheds new light on infection control and immune disorders.    view more (2009-11-20)

New strategy in tumor treatment
A new strategy proposed by researchers at Dartmouth Medical School and Amtek, Hanover, NH may treat tumors that do not respond to conventional treatment.   view more (2009-07-20)

Single microRNA fine-tunes innate immune response
A single microRNA, microRNA-223, in mice controls the production and activation of granulocytes, white blood cells essential for host defense against invading pathogens.   view more (2008-02-20)

Protein from the wrong side of the tracks aids cancer virus
A protein made by a cancer-causing virus using an unusual gene enables that virus to infect immune cells and persist in the host, new research shows.   view more (2006-06-12)

Interactive gene 'networks' may predict if leukemia is aggressive or slow-growing
Rather than testing for individual marker genes or proteins, researchers at the University of California, San Diego (UC San Diego) and the Moores UCSD Cancer Center have evidence that groups, or networks, of interactive genes may be more reliable in determining the likelihood that a form of leukemia is fast-moving or slow-growing.   view more (2008-12-09)
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