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Promising target for new atherosclerosis therapies linked to leukemia
In recent years, scientists studying inflammation and atherosclerosis have seen their respective fields converging. Inflammation is an aspect of the immune response to injury and disease; atherosclerosis, with its characteristic lesions in the blood vessel walls, underlies most cardiovascular disease, including heart attacks and strokes.   view more (2006-11-02)

Researchers find first evidence of virus in malignant prostate cells
In a finding with potentially major implications for identifying a viral cause of prostate cancer, researchers at the University of Utah and Columbia University medical schools have reported that a type of virus known to cause leukemia and sarcomas in animals has been found for the first time in malignant human prostate cancer cells.   view more (2009-09-08)

Stem cell protein offers a new cancer target
A protein abundant in embryonic stem cells is now shown to be important in cancer, and offers a possible new target for drug development, report researchers from the Stem Cell Program at Children's Hospital Boston.   view more (2009-06-02)

Mouse study reveals human X-SCID gene therapy poses substantial cancer risk
New animal studies conducted at the Salk Institute for Biological Studies show that the only human gene therapy treatment to date considered to be largely successful, is, in fact, riskier than realized.   view more (2006-04-27)

Children's Hospital Oakland scientists first to discover new source for harvesting stem cells
A groundbreaking study conducted by Children's Hospital & Research Center Oakland is the first to reveal a new avenue for harvesting stem cells from a woman's placenta, or more specifically the discarded placentas of healthy newborns.   view more (2009-06-23)

New insights into the regulation of PTEN tumor suppression function
The PTEN tumor suppressor gene controls numerous biological processes including cell proliferation, cell growth and death. But PTEN is frequently lost or mutated; in fact, alteration of the gene is so common among various types of human cancer that PTEN has become one of the most frequently mutated of all tumor suppressors.   view more (2008-08-21)

Study uncovers mutation responsible for Noonan Syndrome
Scientists have discovered that mutations in a gene known as SOS1 account for many cases of Noonan syndrome (NS), a common childhood genetic disorder which occurs in one in 1,000-2,500 live births.   view more (2006-12-05)

National study improves outcome for pediatric AML
A new strategy for treating childhood acute myeloid leukemia (AML) based on the individual patient's risk of failure, and guided by the results of a highly sensitive technique for identifying leukemic cells, yielded one-year survival rates of almost 90 percent.   view more (2005-12-14)

The good and bad side of anti-cancer compounds
Compounds known as "HDAC inhibitors" exhibit cancer-killing activities in cultured cells. While they are currently being tested as anti-cancer agents in clinical trials, just how they execute their effects is unclear.   view more (2008-04-11)

Growth factors given with chemotherapy associated with increased risk of blood diseases
Women with breast cancer who receive compounds that stimulate white blood cell production to help their bodies better tolerate chemotherapy are at an increased risk of developing a type of leukemia or a condition called myelodysplastic syndrome.   view more (2007-02-07)

Novel cancer drug reduces neuroblastoma growth by 75 percent
Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have found a new drug that restricts the growth of neuroblastoma, a childhood brain cancer.   view more (2009-04-24)

Drug has ability to cure type of leukemia
In people with chronic myeloid leukemia (CML), the drug Imatinib has been shown to drive cancer into remission, but the disease often returns when treatment is stopped.   view more (2007-10-03)

From mother to daughters: A central mystery in cell division solved
Researchers from the Ludwig Institute for Cancer Research at the University of California, San Diego School of Medicine have identified a key step required for cell division in a study that could help improve therapies to treat cancer.   view more (2008-12-09)

Mass. General study finds potential ovarian cancer stem cells
Massachusetts General Hospital (MGH) researchers have identified potential ovarian cancer stem cells, which may be behind the difficulty of treating these tumors with standard chemotherapy.   view more (2006-07-24)

Cancer Cell Detection Technology Wins Kaye Award For Hebrew University Researchers
A unique technology for optoelectronic detection of the presence of cancer cells has been developed at the Hebrew University of Jerusalem by a team of researchers headed by Itamar Willner, Enrique Berman Professor of Solar Energy at the Institute of Chemistry. The technology detects the presence of telomerase, an active enzyme appearing in cancer... view more... (2004-06-20)

Novel treatments show improvements in survival and response rates for leukemia and lymphoma
The use of dexamethasone early in the treatment of children with acute lymphoblastic leukemia, the most common type of childhood cancer, may help reduce the risk of relapse.   view more (2008-12-08)

Support for chromosomal theory of cancer found in cancers' development of drug resistance
Thirty-six years into the war on cancer, scientists have not only failed to come up with a cure, but most of the newer drugs suffer from the same problems as those available in the pre-war days: serious toxicity, limited effectiveness and eventual resistance.   view more (2007-06-28)

Drug that battles resistance to leukemia pill Gleevec 'extremely effective' against cancer
An experimental therapy that battles drug resistance in Chronic Myeloid Leukemia (CML) has proved "extremely effective" in fighting cancer, giving patients for whom all conventional therapies have failed another option.   view more (2006-06-15)

Researchers find way to make tumor cells easier to destroy
Tumors have a unique vulnerability that can be exploited to make them more sensitive to heat and radiation, researchers at Washington University School of Medicine in St. Louis report.   view more (2008-05-07)

Process controlling T cell growth and production identified
Identifying one of the processes that plays a role in naïve and memory T-cells' growth and production could one day lead to better vaccines and possibly more effective cancer immunotherapy.   view more (2009-05-04)
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