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Cancer scientists create 'human' leukemia process to map how disease begins, progresses
Cancer researchers led by Dr. John Dick at Ontario Cancer Institute (OCI) have developed a method to convert normal human blood cells into "human" leukemia stem cells.   view more (2007-04-27)

Data suggesting that omacetaxine can eradicate leukemic stem cells may offer a breakthrough for CML
Data showing the ability of omacetaxine to kill leukemic stem cells in mouse models with drug-resistant chronic myelogenous leukemia (CML) are the subject of an advance online publication in the journal Leukemia, ChemGenex Pharmaceuticals Limited (ASX:CXS and NASDAQ:CXSP) announced today.   view more (2009-03-27)

Data suggesting that omacetaxine can eradicate leukemic stem cells may offer a breakthrough for CML
Data showing the ability of omacetaxine to kill leukemic stem cells in mouse models with drug-resistant chronic myelogenous leukemia (CML) are the subject of an advance online publication in the journal Leukemia, ChemGenex Pharmaceuticals Limited (ASX:CXS and NASDAQ:CXSP) announced today.   view more (2009-03-26)

UK leads race to produce world's first clinical grade stem cells
The University of Sheffield has received a £2.6m grant to create some of the world's first embryonic stem cell lines that can be used for medicinal purposes.   view more (2005-03-16)

Master regulatory gene found that guides fate of blood-producing stem cells
Researchers from the University of Pennsylvania School of Medicine found that a protein called NF-Ya activates several genes known to regulate the development of hematopoietic stem cells (HSC), or blood-producing stem cells, in bone marrow.   view more (2005-08-02)

Stem cell identity in culture may strongly depend on the cellular microenvironment
Identification, isolation and large scale culture of stem cells for potential medical applications is a major challenge in cell biology.   view more (2007-04-25)

MDC scientists show how hematopoietic stem cell development is regulated
During cell division, whether hematopoietic stem cells (HSCs) will develop into new stem cells (self-renewal) or differentiate into other blood cells depends on a chemical process called DNA methylation.   view more (2009-10-07)

Xie Lab demonstrates the role of microRNA pathway
Ting Xie, Ph.D., Associate Investigator, and Zhigang Jin, Ph.D., Postdoctoral Research Associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary.   view more (2007-02-16)

CDX2 — A protein that promotes leukemia
Researchers from Harvard Medical School, Boston, have found that most individuals with acute myeloid leukemia (AML) inappropriately express a protein known as CDX2 in their leukemic cells.   view more (2007-03-08)

'It is time for scientists to make the case for stem-cell research' (p 113)
Stem-cell research-and its political, legal, and ethical implications-is the theme of this week's issue of THE LANCET. An editorial comments how scientists need to step forward and engage the public to make the case for the future benefits of stem-cell research. 'But convincing critics of the value of embryonic stem cells poses especially... view more... (2004-07-07)

National study improves outcome for pediatric AML
A new strategy for treating childhood acute myeloid leukemia (AML) based on the individual patient's risk of failure, and guided by the results of a highly sensitive technique for identifying leukemic cells, yielded one-year survival rates of almost 90 percent.   view more (2005-12-14)

Leukemic cells find safe haven in bone marrow
The cancer drug asparaginase fails to help cure some children with acute lymphoblastic leukemia (ALL) because molecules released by certain cells in the bone marrow counteract the effect of that drug, according to investigators at St. Jude Children's Research Hospital.   view more (2007-03-23)

U of MN researchers use human embryonic stem cells to kill cancer cells
For the first time, stem cell researchers at the University of Minnesota have coaxed human embryonic stem cells to create cancer-killing cells in the laboratory, paving the way for future treatments for various types of cancers (or tumors).   view more (2005-10-12)

Faults in newly discovered breast stem cells may lead to tumours
Victorian Breast Cancer Research Consortium scientists from The Walter and Eliza Hall Institute, using a mouse model, have discovered the rare stem cell that drives the formation of all breast tissue.   view more (2006-01-05)

Hopes for new cell therapies 'stem' from Sheffield
The Centre for Stem Cell Biology (CSCB) at the University of Sheffield is welcoming some of the world's leading experts to its International Human Embryonic Stem Cell Symposium on Friday 9 July 2004. The CSCB is a world-leading centre for stem cell research, and has produced two of the UK's six embryonic stem cell lines. The symposium will allow... view more... (2004-07-06)

First use of antibody and stem cell transplantation to successfully treat advanced leukemia
For the first time, researchers at Fred Hutchinson Cancer Research Center have reported the use of a radiolabeled antibody to deliver targeted doses of radiation, followed by a stem cell transplant, to successfully treat a group of leukemia and pre-leukemia patients for whom there previously had been no other curative treatment options.   view more (2009-11-06)

Rice University's Baker Institute experts available to discuss stem cell research, recommendations
Rice University's Baker Institute has experts available to discuss the current debate on United States' embryonic stem cell policy.   view more (2009-02-18)

UBC research finds molecular
University of British Columbia researchers have discovered a "molecular key" that could help increase the success of blood stem cell transplants, a procedure currently used to treat diseases such as leukemia, Hodgkin's lymphoma and aplastic anemia.   view more (2009-04-23)

USC stem cell study sheds new light on cell mechanism
Research from the University of Southern California (USC) has discovered a new mechanism to allow embryonic stem cells to divide indefinitely and remain undifferentiated.   view more (2008-05-22)

A link between mitochondria and tumor formation in stem cells
Researchers report on a previously unknown relationship between stem cell potency and the metabolic rate of their mitochondria -a cell's energy makers. Stem cells with more active mitochondria also have a greater capacity to differentiate and are more likely to form tumors.   view more (2008-10-13)
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