Liver Disease Current Events | Liver Disease News | 10
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The risk factors of idiopathic pulmonary fibrosis in HCV patients
Hepatitis C virus (HCV) is one of the more common causes of chronic liver disease in world with a variety of extrahepatic complications such as essential mixed cryoglobulinemia, membranoproliferative glomerulonep hritis, autoimmune thyroiditis, sialadenitis, and cardiomyopathy. view more (2008-10-23)
A novel method of isolating high quality RNA from Kupffer cells
Kupffer cells, resident tissue macrophages that line the liver sinusoids, play a key role in modulating inflammation in a number of experimental models of liver injury. view more (2009-04-17)
Protective action of a molecule in inflammatory processes discovered
Henar Hevia Pérez, researcher in the area of Genic Therapy and Hepatology at the Applied Medicine Research Centre (CIMA)of the University of Navarra, has discovered the protective role of the methylthioadenosine (MTA) molecule in an in vivo inflammation model. view more (2006-04-27)
Pittsburgh scientists find protein may be key to new therapies for elevated triglycerides
Diabetes researchers at the John G. Rangos Sr. Research Center at Children's Hospital of Pittsburgh of UPMC have identified a potential target for the development of new therapies to treat hypertriglyceridemia, a lipid disorder commonly seen in people who are obese and diabetic. view more (2008-05-27)
Gene variant boosts risk of fatty liver disease, scientists discover
Researchers at UT Southwestern Medical Center have found that individuals who carry a specific form of the gene PNPLA3 have more fat in their livers and a greater risk of developing liver inflammation. view more (2008-09-26)
Fat collections linked to decreased heart function
Researchers from Boston University School of Medicine (BUSM) have shown that fat collection in different body locations, such as around the heart and the aorta and within the liver, are associated with certain decreased heart functions. view more (2009-11-16)
Proteomic profiling shown more accurate than traditional biomarkers in identifying liver cancer
As the incidence of liver cancer continues to grow-- fueled in large part, by rising rates of hepatitis C infections - so too does the need for tests to help diagnose the disease at an earlier stage. view more (2008-01-15)
Making headway against hepatitis C: SLU study shows new drug combo effective in non-responders
Saint Louis University Liver Center scientists are presenting research today on a more effective way to treat hepatitis C patients who have been unresponsive to current drug therapies. view more (2006-10-30)
Transplanted liver cells function in older animals but do not proliferate as much as in younger ones
When things go right, transplanted healthy liver cells transplanted by infusion or injection will find their way to the liver, integrate into the damaged tissue, start proliferating, and take over the liver's work of helping with digestion and removing waste products and worn-out cells from the blood. view more (2009-04-20)
New toxicity test could cut animal testing
To test whether chemicals are toxic to humans, researchers need to use liver cells that have been freshly harvested from mice or other mammals. A new collection of stable cell lines, described in BMC Biotechnology this week, could reduce the numbers of animals needed in such experiments. The MMH-GH cell lines are derived from the liver cells of... view more... (2004-03-17)
USC study shows belly fat may affect liver function
A study by the University of Southern California (USC) suggests the release of lipids from abdominal fat, which drains directly to the liver, increases overnight, providing additional insight as to how abdominal fat is associated with type 2 diabetes risk. The results of the study were presented at an oral session Monday, June 9 at the American... view more... (2008-06-10)
Old diabetes drug teaches experts new tricks
Research from the Johns Hopkins Children's Center reveals that the drug most commonly used in type 2 diabetics who don't need insulin works on a much more basic level than once thought, treating persistently elevated blood sugar - the hallmark of type 2 diabetes - by regulating the genes that control its production. view more (2009-05-15)
Novel antibody prevents infection by hepatitis C virus
Taking aim at a leading cause of liver failure in the United States, a team of scientists at the Massachusetts Biologic Laboratories (MBL) of the University of Massachusetts Medical School (UMMS) has developed a human monoclonal antibody that neutralizes the Hepatitis C virus (HCV). view more (2009-05-06)
Scientists develop novel method to generate functional hepatocytes for drug testing
Scientists have for the first time produced liver cells from adult skin cells using the induced pluripotent stem cell (iPSC) technology. view more (2009-10-21)
May hepatic granulomas be part of the histological spectrum of chronic hepatitis C?
While older large series of patients with hepatic granulomas have found sarcoidosis and tuberculosis to be the most common causes of hepatic granulomas, recent works have noted some patients with chronic hepatic C and hepatic granulomas and no other obvious associations. view more (2008-12-29)
Omega-3 fatty acids inhibit growth of liver cancer cells
Two new studies by a University of Pittsburgh research team suggest that omega-3 fatty acids-substances that are found in high concentrations in fish oils and certain seeds and nuts-significantly inhibit the growth of liver cancer cells. view more (2006-04-03)
Doubling of deaths from alcoholic liver disease - drug abuse during 1970s and 1980s may explain why
Middle-aged men could be at increased risk of death from liver disease, as a result of illicit intravenous drug use during the 1970s and 1980s, according to a study published today. view more (2002-07-31)
Liver CRP production linked to atherosclerosis
New research shows that levels of C-reactive protein (CRP), produced by the liver and not at the lesion site, correlate with the degree of atherosclerosis. view more (2005-09-29)
Who found some new mechanisms of HBV virulence?
This dreadful HBV is small in size. The genome of this virus is a partial double stranded circle. When made fully double stranded, this genome carries about 3000 base pairs, compared to 200 kilo base pairs of the genome of the smallpox virus. view more (2008-02-25)
Developing a safer form of acetaminophen
Scientists in Louisiana are reporting development of a process for producing large batches of a new and potentially safer form of acetaminophen, the widely used pain-reliever now the source of growing concern over its potentially toxic effects on the liver. view more (2009-07-16)
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