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Rare Domino Transplant Allows Children's Hospital of Pittsburgh and UPMC Surgeons to Save Two Lives With One Deceased Donation Transplant surgeons at Children's Hospital of Pittsburgh and UPMC have saved two patients with life-threatening liver conditions utilizing a technique known as a domino transplant. It is only the nation's second domino transplant involving a patient with maple syrup urine disease (MSUD). view more (2006-10-04)
New University company HepCgen marks National Hepatitis C Awareness Day July 1st (Southampton UK, June 30, 2003) HepCgen, specialising in diagnostics and treatments for chronic liver disease, and recently founded out of the University of Southampton, recognises the importance of the National Hepatitis C Awareness Day Initiative. Liver disease specialist Dr William Rosenberg, who has worked and researched in this field for 15... view more... (2003-06-30)
Liver Cancer Linked to Cellular Repair Pathway The unchecked activity of a cell signaling pathway crucial in embryonic development and the liver's response to injury leads to liver cancer. view more (2006-03-30)
OHSU turns mouse into factory for human liver cells Oregon Health & Science University researchers have figured out how to turn a mouse into a factory for human liver cells that can be used to test how pharmaceuticals are metabolized. view more (2007-08-10)
Chemotherapy given directly to the liver improves survival for patients with colorectal cancer A new study shows that patients whose colorectal cancer has spread to the liver who received an approach called hepatic arterial infusion (HAI)- the administration of chemotherapy directly to the liver through a pump in the abdomen-fare better than those who received traditional, intravenous chemotherapy. view more (2006-02-28)
UCLA/VA develops tool to gauge quality of life of hepatitis B patients "Am I going to die" I have no future." "I feel depressed at times, fearful I may not see my children marry or be a grandparent." Such heart-rending statements from patients with chronic hepatitis B reveal the social and mental impact of this disease, which affects 350 million worldwide. view more (2007-07-11)
Older liver donors not associated with negative outcomes in transplant recipients with hepatitis C Receiving a liver from a donor older than age 60 does not appear to be associated with transplant failure, death or recurrent disease in the next five years among transplant patients with the hepatitis C virus. view more (2008-07-22)
POOR PREDICTION OF OSTEOPOROSIS AFTER HEART OR LIVER TRANSPLANTATION (pp 325, 342) The lack of identification of clear risk factors for osteoporotic fractures after organ transplantation reported in this week’s issue of THE LANCET suggests that future post-transplantation treatment should aim to prevent osteoporosis. Osteoporosis and related fractures are a major complication after organ transplantation. Gudrun... view more... (2001-01-31)
Radiation, chemotherapy with liver transplant improves cancer survival A new treatment for patients with a type of bile duct cancer promises a greater chance at survival by combining radiation, chemotherapy and liver transplantation, Mayo Clinic physicians report in the September issue of the Annals of Surgery. view more (2005-09-12)
Stanford scientist to discuss new approach to treating hepatitis C virus Last year Peter Sarnow, PhD, professor of microbiology and immunology at the Stanford University School of Medicine, identified a previously unknown mechanism that the hepatitis C virus uses to replicate, yielding a promising new approach to combating the disease-causing virus. view more (2006-04-06)
Advances in liver surgery enable the prospect of curative treatment for more patients Although many prognostic factors predicting survival and cancer recurrence in patients undergoing surgery for colorectal liver metastases are already identified, the effects of newly introduced technologies and new drugs in the treatment of these patients are still poorly studied because of the presence of many involved factors. view more (2009-06-15)
Feather color is more than skin deep Where do birds get their red feathers from? According to Esther del Val, from the National History Museum in Barcelona, Spain, and her team, the red carotenoids that give the common crossbill (Loxia curvirostra) its red coloration are produced in the liver, not the skin, as previously thought. view more (2009-04-16)
Liver regeneration may be simpler than previously thought The way the liver renews itself may be simpler than what scientists had been assuming. A new study, appearing in the April 13 issue of The Journal of Biological Chemistry, provides new information on the inner workings of cells from regenerating livers that could significantly affect the way physicians make livers regrow in patients with liver... view more... (2007-04-12)
Researchers uncover mechanisms leading to portal hypertension A physician-scientist at UT Southwestern Medical Center and his research team have identified mechanisms causing a potentially deadly type of hypertension that results from liver damage-findings that could lead to its prevention. view more (2005-09-30)
Noninvasive tests for cirrhosis may help to avoid liver biopsy Newer ultrasound and magnetic resonance (MR) imaging tests yield encouraging initial results in diagnosing fibrosis (scarring) and cirrhosis of the liver, according to three studies in the October issue of the journal Clinical Gastroenterology and Hepatology. view more (2007-10-02)
200 proteins which detect diseases of the liver The biochemist Enrique Santamaría Martínez, a researcher in the area of Genetic Therapy and Hepatology at the CIMA of the University of Navarra, has identified more than 200 proteins which can be considered as indicators of the progression of steatohepatitis and liver hepatitis. view more (2005-12-14)
Researchers Find New Treatment for Hepatitis C Researchers at the OU Health Sciences Center have found a new use for an old drug. Their findings appear online Friday in the American Journal of Gastroenterology. view more (2008-05-15)
Fatty acids and caveolin-1 are essential in liver regeneration Liver regulates lipid, carbohydrate and protein metabolism. It also segregates a number of proteins and enzymes, and eliminates toxic substances from the organism. Liver regeneration is a mostly unknown process at a molecular level, although it is essential for the good functioning of the liver, and indispensable in order to carry out some... view more... (2006-09-19)
Regulating the sugar factory in diabetes Scientists in Sydney and Boston believe they may have identified a gene that controls abnormal production of sugar in the liver, a very troublesome problem for people with diabetes. view more (2009-05-21)
A potential therapeutic strategy for hepatic failure Fulminant hepatic failure is a serious clinical disease and may threaten the life of patients. However, because of the damage of mass liver cells, the organ function is often irreversible due to the liver cell degeneration, swelling, or apoptosis. Thus, to supply new sources of functional liver cells is a valuable choice for these patients. view more (2009-03-31)
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