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Liver Dysfunction Current Events | Liver Dysfunction News | 11

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First human gets new antibody aimed at hepatitis C virus
Building upon a series of successful preclinical studies, researchers at MassBiologics of the University of Massachusetts Medical School (UMMS) today announced the beginning of a Phase 1 clinical trial, testing the safety and activity of a human monoclonal antibody they developed that can neutralize the Hepatitis C virus (HCV).   view more (2009-08-07)

A breakthrough in contrast-enhanced intraoperative ultrasonography
The present brief clinical report showed that Contrast-enhanced intraoperative ultrasonography (CE-IOUS) using a new microbubble agent, Sonazoid, can allow surgeons to investigate the whole liver with enough time and to find new metastases intraoperatively.   view more (2008-09-18)

Mathematical model identifies genes which battle hepatitis C
Joint research by Dr. Leonid Brodsky, of the Institute of Evolution of the University of Haifa, and Dr. Milton Taylor, of Indiana University, led to the discovery of a mathematical method which can identify which genes in our bodies conduct the battle against the various viruses that attack us.   view more (2007-07-20)

Researchers show that fibrosis can be stopped, cured and reversed
University of California, San Diego researchers have proven in animal studies that fibrosis in the liver can be not only stopped, but reversed.   view more (2007-12-27)

Tobacco Smoke and Alcohol Harm Liver Worse as Combo
Exposure to second-hand smoke and alcohol significantly raises the risk of liver disease, according to researchers at the University of Alabama at Birmingham (UAB).   view more (2009-02-04)

Increasing the success of liver transplants by managing levels of anti-rejection drugs
Approximately 600 children receive liver transplants each year in the United States. The use of immunosuppressant drug therapy, namely calcineurin inhibitors (CNIs) such as cyclosporine and tacrolimus, has decreased the risk of liver rejection and increased patient survival rates.   view more (2005-06-13)

Metabolic syndrome linked to liver disease in obese teenaged boys
Researchers studying a large sample of adolescent American boys have found an association between metabolic syndrome, which is a complication of obesity, and elevated liver enzymes that mark potentially serious liver disease.   view more (2009-09-30)

Double the death rate from cirrhosis for 'blue collar' men
School of Population Health Professors Jake Najman and Gail Williams and Stockholm University's Professor Robin Room examined death rates among Australian men from liver cirrhosis between 1981 and 2002.   view more (2007-05-10)

Tadalafil shows promise for relief of lower urinary tract symptoms associated with BPH
Men with signs of benign prostatic hyperplasia (BPH) can be helped with a daily dose of erectile dysfunction drug tadalafil (Cialis®) to relieve associated lower urinary tract symptoms (LUTS), according to a new study published in the October 2008 issue of The Journal of Urology.   view more (2008-08-19)

Melatonin may be served as a potential anti-fibrotic drug
In China, the incidence of liver cirrhosis is still high. Liver cirrhosis results from fibrosis. If treated properly at fibrosis stage, cirrhosis can be prevented.   view more (2009-03-31)

NEW DRUG TREATMENT COULD PROVIDE LONG-TERM BENEFIT FOR HEART-ATTACK PATIENTS (p 1385)
Patients with acute myocardial infarction (heart attack), complicated by left-ventricular systolic dysfunction, could benefit from the ß-blocker carvedilol, conclude authors of a study in this week's issue of THE LANCET. In a randomised, placebo-controlled trial, this drug reduced the frequency of death from all causes, death from... view more... (2001-05-03)

Advances in liver surgery enable the prospect of curative treatment for more patients
Although many prognostic factors predicting survival and cancer recurrence in patients undergoing surgery for colorectal liver metastases are already identified, the effects of newly introduced technologies and new drugs in the treatment of these patients are still poorly studied because of the presence of many involved factors.   view more (2009-06-15)

A potential therapeutic strategy for hepatic failure
Fulminant hepatic failure is a serious clinical disease and may threaten the life of patients. However, because of the damage of mass liver cells, the organ function is often irreversible due to the liver cell degeneration, swelling, or apoptosis. Thus, to supply new sources of functional liver cells is a valuable choice for these patients.   view more (2009-03-31)

Liver disease responsible for most alcohol-related illness and deaths
Liver disease is the most prevalent cause of alcohol-related deaths, followed by car accidents and cancer, according to new research conducted in Portugal and presented today at EASL 2009, the Annual Meeting of the European Association for the Study of Liver in Copenhagen, Denmark.   view more (2009-04-23)

Targeting Tumor Behavior May Lead To New Liver Cancer Drugs
Ohio State University cancer researchers have used computational and genomic methods to identify possible anti-cancer agents that may block a particular kind of tumor behavior.   view more (2009-06-19)

Why could prednisolone suppress the hepatic ischemia-reperfusion injury?
Hepatic ischemia-reperfusion injury is a serious complication but unavoidable problem in liver surgery including liver transplantation and hepatic resection.   view more (2008-10-08)

Large DNA stretches, not single genes, shut off as cells mature
Experiments at Johns Hopkins have found that the gradual maturing of embryonic cells into cells as varied as brain, liver and immune system cells is apparently due to the shut off of several genes at once rather than in individual smatterings as previous studies have implied.   view more (2009-01-20)

Cure for hepatitis C announced by VCU researcher
The use of peginterferon alone, or in combination with ribavirin, points to a cure for hepatitis C, the leading cause of cirrhosis, liver cancer and the need for liver transplant, a Virginia Commonwealth University researcher said today.   view more (2007-05-22)

New Jefferson Trial to Test Radiation-Emitting Beads Against Advanced Liver Cancer
Liver cancer specialists at Jefferson's Kimmel Cancer Center in Philadelphia are beginning an 18-month study of a new treatment for liver cancer. The therapy entails injecting tiny beads that emit small amounts of radiation into the liver's main artery while also blocking the blood supply feeding the cancer's growth.   view more (2008-02-13)

Blood marker helps predict prognosis among those with abdominal infection
Monitoring blood levels of a compound known as procalcitonin in patients with peritonitis (a serious intra-abdominal infection) could help identify patients at increased risk of organ failure and death.   view more (2007-02-20)
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