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Liver Dysfunction Current Events | Liver Dysfunction News | 9

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A new finding in liver transplantation and antifibrinolytics?
Orthotopic liver transplantation (OLT) is associated with severe bleeding and considerable transfusion requirements. There are several reasons for this severe bleeding in OLT. Hemostatic abnormalities remain a major cause.   view more (2008-03-13)

A promising new approach to cadmium induced hepatoxicity: Cytoprotective effect of midkine
Cadmium comes from a wide variety of sources in the environment and from industry and is extremely toxic to humans. Environmental exposure can occur via the diet and drinking water.   view more (2008-01-17)

Causes for sexual dysfunction change as people age
Sexual dysfunction is not an inevitable part of aging, but it is strongly related a number of factors, such as mental and physical health, demographics and lifetime experiences, many of which are interrelated, according to a new study by researchers at the University of Chicago.   view more (2008-08-13)

The right kind of oil
Children who cannot eat on their own because of intestinal failure must rely on parenteral nutrition (PN), an intravenous method of feeding.   view more (2006-07-05)

A new method for bone-marrow-derived liver stem cells isolation and proliferation
Great interest has been aroused in the identification and isolation of liver stem cells from bone marrow cells. Several subsets of bone marrow cells have been found to have the potential to differentiate into hepatocytes, however, sorting based on immunological methods is difficult because of the complicated surface markers of the stem cells;... view more... (2009-04-15)

Cancer-fighting virus shows promise in early clinical trial
A virus that has been specifically designed by scientists to be safe to normal tissue but deadly to cancer is showing early promise in a preliminary study, researchers said today at the ESMO Conference Lugano (ECLU), Switzerland.   view more (2007-07-09)

Antibiotics: Single largest class of drugs causing liver injury
Antibiotics are the single largest class of agents that cause idiosyncratic drug-induced liver injury (DILI), reports a new study in Gastroenterology, an official journal of the American Gastroenterological Association (AGA) Institute.   view more (2008-12-01)

A novel method of isolating high quality RNA from Kupffer cells
Kupffer cells, resident tissue macrophages that line the liver sinusoids, play a key role in modulating inflammation in a number of experimental models of liver injury.   view more (2009-04-17)

Children's Hospital 1 of 10 pediatric hospitals in US selected to study liver disease in kids
Children's Hospital of Pittsburgh of UPMC has been selected to join an effort among select centers in the United States and Canada to collect and study information necessary to understand the possible causes and treatment of a destructive liver disease called primary sclerosing cholangitis (PSC).   view more (2008-02-27)

Fatty liver linked to increased risk of diabetic kidney disease
For patients with type 2 diabetes, a condition called non-alcoholic fatty liver disease (NAFLD) may be an important risk factor for diabetes-related chronic kidney disease (CKD), according to a study in the August Journal of the American Society of Nephrology (JASN).   view more (2008-05-30)

Protective action of a molecule in inflammatory processes discovered
Henar Hevia Pérez, researcher in the area of Genic Therapy and Hepatology at the Applied Medicine Research Centre (CIMA)of the University of Navarra, has discovered the protective role of the methylthioadenosine (MTA) molecule in an in vivo inflammation model.   view more (2006-04-27)

1 surgery better than 2 for some colorectal cancer patients
A single surgery to remove cancer from both the colon and the liver to which it has spread may be better in some cases than the current standard treatment of two separate surgeries with chemotherapy in between, according to a study led by Duke University Medical Center researchers.   view more (2007-03-19)

Abnormal heart function associated with reduced capacity for exercise
Patients with abnormal diastolic function (when the heart is relaxed and expanded) in the left ventricle of the heart have a substantially lower maximum capacity for exercise, according to a study in the January 21 issue of JAMA.   view more (2009-01-21)

Toward explaining why hepatitis B hits men harder than women
Scientists in China are reporting discovery of unusual liver proteins, found only in males, that may help explain the long-standing mystery of why the hepatitis B virus (HBV) sexually discriminates -- hitting men harder than women.   view more (2009-11-19)

'Supersize me' mice research offers grim warning for America's fast food consumers
It's research that may have you thinking twice before upgrading to the large size at your favorite fast food joint. Saint Louis University research presented this week in Washington, D.C., shows the dangers of high-fat food combined with high fructose corn syrup and a sedentary lifestyle - in other words, what may be becoming commonplace among... view more... (2007-05-24)

Mayo Clinic Proceedings contributors discuss impact of donor organ allocation system
Liver transplant is a life saving treatment option for people with end-stage liver disease. Unfortunately, the need for donor livers far exceeds the supply.   view more (2008-02-07)

Brain function and negative thinking linked to late-onset depression
Late-onset depression, which first emerges in people aged 60 and over, is linked to a decline in the brain's executive functions that leads to repetitive, negative thought patterns a new study reveals.   view more (2006-06-26)

Transplanted liver cells function in older animals but do not proliferate as much as in younger ones
When things go right, transplanted healthy liver cells transplanted by infusion or injection will find their way to the liver, integrate into the damaged tissue, start proliferating, and take over the liver's work of helping with digestion and removing waste products and worn-out cells from the blood.   view more (2009-04-20)

Personalized diets may offer relief to advanced cancer patients
It is well known that cancer patients undergoing chemotherapy and radiation therapy often experience nausea and loss of appetite. But until now, few researchers have looked into why this happens and what can be done to ensure that cancer patients maintain a healthy diet during treatment.   view more (2007-03-12)

New toxicity test could cut animal testing
To test whether chemicals are toxic to humans, researchers need to use liver cells that have been freshly harvested from mice or other mammals. A new collection of stable cell lines, described in BMC Biotechnology this week, could reduce the numbers of animals needed in such experiments. The MMH-GH cell lines are derived from the liver cells of... view more... (2004-03-17)
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