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Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
Current cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual... view more... (2007-06-18)

Scientists make first step towards growing human lungs for transplant
Scientists have successfully converted human embryonic stem cells into lung cells, taking a first step towards building human lungs for transplantation.   view more (2005-08-23)

Penn researchers find key developmental pathway activates lung stem cells
Researchers from the University of Pennsylvania School of Medicine found that the activation of a molecular pathway important in stem cell and developmental biology leads to an increase in lung stem cells. Harnessing this knowledge could help develop therapies for lung-tissue repair after injury or disease.   view more (2008-06-18)

Stem cell therapy may offer hope for acute lung injury
Researchers at the University of Illinois at Chicago College of Medicine have shown that adult stem cells from bone marrow can prevent acute lung injury in a mouse model of the disease.   view more (2009-10-29)

A link between mitochondria and tumor formation in stem cells
Researchers report on a previously unknown relationship between stem cell potency and the metabolic rate of their mitochondria -a cell's energy makers. Stem cells with more active mitochondria also have a greater capacity to differentiate and are more likely to form tumors.   view more (2008-10-13)

Umbilical cord blood stem cell transplant may help lung, heart disorders
Two separate studies published in the current issue of Cell Transplantation (18:8), - now freely available on-line have shown that transplanted human-derived umbilical cord blood (UCB) stem cells transplanted in an animal model had positive therapeutic effects on specific lung and heart disorders the animal models.   view more (2009-11-24)

Activated stem cells in damaged lungs could be first step toward cancer
Stem cells that respond after a severe injury in the lungs of mice may be a source of rapidly dividing cells that lead to lung cancer, according to a team of American and British researchers.   view more (2009-05-27)

U of MN researchers turn cord blood into lung cells
Researchers at the University of Minnesota have, for the first time, coaxed umbilical cord blood stem cells to differentiate into a type of lung cell.   view more (2006-11-02)

UCLA cancer researchers develop model that may help identify cancer stem cells
Researchers at UCLA's Jonsson Comprehensive Cancer Center, on a quest to find lung cancer stem cells, have developed a unique model to allow further investigation into the cells that many believe may be at the root of all lung cancers.   view more (2009-06-16)

Tapping into spinal cures
Stem cells which give rise to vertebrae, muscle and the spinal cord have been identified for the first time by Dr. Valerie Wilson (University of Edinburgh). "These axial stem cells could be used in the future to help replace damaged tissues after back injuries", says Dr. Wilson who will be presenting her work at the Society for... view more... (2004-03-26)

Mice could provide the key to growing human lungs for transplant
Scientists from Imperial College London have successfully directed mouse stem cells to turn into the type of cells needed for gas exchange in lungs, bringing the prospect of being able to regenerate damaged lung tissue, and even the creation of artificially grown lungs one step closer. Dr Anne Bishop, from Imperial College Tissue Engineering and... view more... (2002-05-15)

OU Cancer Institute Scientists Identify New Cancer Stem Cell Marker; Developing Drug to Stop Cancer Recurrence
After years of working toward this goal, scientists at the OU Cancer Institute have found a way to isolate cancer stem cells in tumors so they can target the cells and kill them, keeping cancer from returning.    view more (2008-09-12)

Stem cell identity in culture may strongly depend on the cellular microenvironment
Identification, isolation and large scale culture of stem cells for potential medical applications is a major challenge in cell biology.   view more (2007-04-25)

Xie Lab demonstrates the role of microRNA pathway
Ting Xie, Ph.D., Associate Investigator, and Zhigang Jin, Ph.D., Postdoctoral Research Associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary.   view more (2007-02-16)

From lung to gut - the Wnt signaling pathway transforms cell fate
Researchers have uncovered a cellular mechanism that can alter the fate of progenitor cells that normally generate the lung, causing them to create gut cells instead. The findings, which are published this week in the top-tier Open Access journal, Journal of Biology, could help researchers hoping to use adult stem cells for therapeutic purposes.... view more... (2004-06-03)

Could skin cells become brain cells? (p 172)
Results of an experimental study in this week's issue of THE LANCET highlight how adult skin cells can be made into precursor nerve cells, with potential implications for the future treatment of neurodegenerative disorders such as Parkinson's disease. Ethical and practical considerations limit the availability of neural stem cells derived from... view more... (2004-07-07)

Cancer stem cells: know thine enemy
Stem cells -- popularly known as a source of biological rejuvenation -- may play harmful roles in the body, specifically in the growth and spread of cancer.   view more (2007-12-26)

Scientists can now differentiate between healthy cells and cancer cells
One of the current handicaps of cancer treatments is the difficulty of aiming these treatments at destroying malignant cells without killing healthy cells in the process.   view more (2009-01-06)

Tissue regeneration operates differently than expected
Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany, in co-operation with colleagues from Martin Luther University in Halle-Wittenberg, have now shown that skeletal muscle tissue can fuse with adult stem cells, via a mechanism based on the participation of mediators which are generally involved in immune... view more... (2005-08-05)

U of MN researchers use human embryonic stem cells to kill cancer cells
For the first time, stem cell researchers at the University of Minnesota have coaxed human embryonic stem cells to create cancer-killing cells in the laboratory, paving the way for future treatments for various types of cancers (or tumors).   view more (2005-10-12)
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