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Mice could provide the key to growing human lungs for transplant
Scientists from Imperial College London have successfully directed mouse stem cells to turn into the type of cells needed for gas exchange in lungs, bringing the prospect of being able to regenerate damaged lung tissue, and even the creation of artificially grown lungs one step closer. Dr Anne Bishop, from Imperial College Tissue Engineering and... view more... (2002-05-15)

Study identifies new tumor suppressor
A protein called HLJ1 may work as a novel tumor suppressor in non-small-cell lung carcinoma.   view more (2006-06-21)

Protein may be strongest indicator of rare lung disease, study shows
Researchers at the University of Cincinnati (UC) have discovered a protein in the lungs that can help in determining progression of the rare lung disease Idiopathic Pulmonary Fibrosis (IPF).   view more (2009-06-04)

Penn researchers find key developmental pathway activates lung stem cells
Researchers from the University of Pennsylvania School of Medicine found that the activation of a molecular pathway important in stem cell and developmental biology leads to an increase in lung stem cells. Harnessing this knowledge could help develop therapies for lung-tissue repair after injury or disease.   view more (2008-06-18)

Knee arthritis link to lung cancer
Arthritis of the knee may be the first sign of a type of lung cancer that is hard to treat in heavy smokers, suggests research published ahead of print in the Annals of the Rheumatic Diseases.   view more (2007-09-04)

Cancer stem cells similar to normal stem cells can thwart anti-cancer agents
Current cancer therapies often succeed at initially eliminating the bulk of the disease, including all rapidly proliferating cells, but are eventually thwarted because they cannot eliminate a small reservoir of multiple-drug-resistant tumor cells, called cancer stem cells, which ultimately become the source of disease recurrence and eventual... view more... (2007-06-18)

New mediator of smoking recruits
Current research suggests that smoking increases the production of osteopontin in the lungs, which contributes to the development of smoking-related lung disease.   view more (2009-04-24)

A tumor suppressor that promotes cancer cell growth?
Researchers have shown that the tumor suppressor gene H-REV107-1 may actually stimulate tumor progression in some non-small cell lung carcinomas.   view more (2006-10-09)

PET scan shows during treatment if radiation is shrinking lung tumor, U-M study shows
Lung cancer patients may not need to wait till their radiation treatment is over to know if it worked. A PET scan several weeks after starting radiation treatment for lung cancer can indicate whether the tumor will respond to the treatment.   view more (2007-07-19)

First report of cancer drug Gleevec as new target therapy for pulmonary hypertension
Gleevec (Imatinib) is a representative of the newest generation of cancer drugs. The substance conveys its potent anti-proliferative effect by selectively supressing the tyrosine kinase pathway.   view more (2005-09-30)

Viruses may play a role in lung cancer development
Papers presented at the 1st European Lung Cancer Conference, jointly organized by the European Society for Medical Oncology (ESMO) and the International Association for the Study of Lung Cancer (IASLC) in Geneva, Switzerland highlight emerging evidence that common viruses may contribute to the development of lung cancer.   view more (2008-04-25)

Gene therapy may protect normal tissues during radiation retreatment for lung cancer
Gene therapy could be used as an agent to protect normal tissues, including the esophagus and lung, from damage during a second administration of radiation therapy for non-small cell lung cancer.   view more (2005-10-17)

Women smokers have higher risk of lung cancer than men smokers, though lower lung cancer death rate
Women who smoke appear to be more susceptible to lung cancer than men who smoke, though women smokers have a lower rate of lung cancer-related death.   view more (2006-07-12)

Researchers identify genes associated with lung transplant rejection
Researchers at the San Francisco VA Medical Center (SFVAMC) and the University of California, San Francisco (UCSF) have identified six genes associated with lymphocytic bronchitis, which is thought to lead to obliterative bronchitis (OB), the most common cause of long-term failure of transplanted lungs.   view more (2005-07-14)

Mouth may tell the tale of lung damage caused by smoking
Cells lining the mouth reflect the molecular damage that smoking does to the lining of the lungs, researchers at The University of Texas M. D. Anderson Cancer Center report today at the annual meeting of the American Association for Cancer Research.   view more (2008-04-14)

Don`t smoke while feeding the birds: new research on lung disease
Scientists are developing a method that could prevent lung infections in people who smoke, according to a paper presented today (Wednesday 18 September) at the Society for General Microbiology autumn meeting at Loughborough University. "We've used a human tissue model to show how we can prevent Mycobacterium avium complex (MAC) bacteria from... view more... (2002-08-28)

Normal tissue not spared in new forms of breast cancer radiotherapy
A five day course of radiotherapy to treat breast cancer may, in some cases, expose as much lung and heart tissue to potentially toxic radiation as does the standard six weeks of treatment, say researchers at Mayo Clinic Jacksonville.   view more (2007-10-31)

Drawing a crowd: Understanding the signals that bring inflammatory cells into the lung
Understanding the connection between influx of immune cells into the lung and acute lung injury is essential, since lung damage tends to occur secondary to increased lung inflammation.   view more (2006-02-17)

Asthma Research Breakthrough Holds Promise Of Cure
New research has made a vital breakthrough in the understanding of how asthma is caused, bringing the possibility of treatments for its prevention and cure.   view more (1999-07-06)

Rare Lung Disease Cells Indicate Higher Death Risk
Large numbers of certain cells in the lungs of patients diagnosed with idiopathic pulmonary fibrosis may increase their chance of death, UC researchers have discovered.   view more (2008-01-17)
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