Lupus Current Events | Lupus News | 2
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UT Southwestern researchers identify roles of gene mutations causing lupus in mice
In two related studies, researchers at UT Southwestern Medical Center have pinpointed defective genes in mice responsible for triggering the mysterious autoimmune disease lupus, which prompts the body's immune system to mistakenly attack healthy organs and tissues. view more (2006-06-16)
Steps toward Stopping Autoimmune Disease
A landmark genetic study has identified multiple genes linked to systemic lupus erythematosus (SLE), or lupus, a debilitating autoimmune disease that affects an estimated 1.4 million Americans. view more (2008-01-21)
Existing drugs show promise for treating end-stage renal disease in lupus
Studies in mice suggest that two drugs already approved by the U.S. Food and Drug Administration show promise for treating the complications of lupus. view more (2007-11-12)
Rheumatic disease increases risks in pregnancy, Stanford study finds
The first nationwide study of pregnancy outcomes in women with rheumatic disease confirms that they experience greater pregnancy risks and longer hospital stays than the average pregnant woman. view more (2005-11-15)
Lupus patients perceive benefit from cardiovascular disease prevention counseling program
According to a new study by Hospital for Special Surgery investigators presented at the American College of Rheumatology meeting on October 21 in Philadelphia, most lupus patients are not aware that their condition puts them at a higher risk for cardiovascular disease and a counseling program is a valuable way to promote education and lifestyle... view more... (2009-10-19)
Research links genetic mutations to lupus
A gene discovered by scientists at Wake Forest University School of Medicine has been linked to lupus and related autoimmune diseases. view more (2007-07-30)
Cancer drug hope for people with lupus
A drug used to treat cancer may also benefit people with lupus who have complications of the central nervous system. Rheumatologists at the Annual European Congress of Rheumatology in Vienna, Austria heard today (Thursday 9 June) that rituximab is the first drug in a quarter of a century that is making a real impact, and an alternative to previous... view more... (2005-06-09)
Antibody-altering protein found in developing B cells
In order for the B cells of the immune system to identify and fight disease pathogens, they produce a protein called activation-induced cytidine deaminase (AID). view more (2007-07-20)
National report shines light on lupus 50-year treatment drought
Today, The Lewin Group, a national health care consulting firm, issued recommendations on ways to overcome the barriers that have obstructed lupus drug development resulting in no new drug approval for this disease in more than 50 years - since the Eisenhower Administration. view more (2009-10-05)
Abnormal 'editing' of gene messages may be a cause of lupus
Researchers at Wake Forest University have uncovered evidence that the abnormal "editing" of gene messages in a type of white blood cell may be behind the development of lupus. view more (2008-05-20)
Research shows promise for using stem cell transplantation to treat patients with severe lupus
About half of patients with severe lupus that was refractory to standard treatment and who underwent autologous stem cell transplantation to improve their immune system have substantial improvement in disease activity after several years. view more (2006-02-01)
Novel DNA vaccine leads to kidney damage prevention in systemic lupus erythematosus models
DNA vaccination using lupus autoantigens and interleukin-10 (IL-10, a cytokine that plays an important role in regulating the immune system) has potential as a novel therapy to induce antigen specific tolerance and may help to prevent kidney damage in patients with systemic lupus erythematosus (SLE). view more (2009-06-12)
UT Southwestern researchers probe kidney damage, protection in lupus
Kidney damage associated with the autoimmune disease lupus is linked to a malfunction of immune cells that causes them to congregate in and attack the organs, researchers at UT Southwestern Medical Center have discovered in a mouse study. view more (2009-04-21)
Clinical trial supports better treatment for lupus nephritis
Treating lupus patients suffering from kidney inflammation with a medicine known as mycophenolate mofetil may be more effective in inducing remission than treating them with the standard regimen of intravenous cyclophosphamide (Cytoxan), a new clinical trial indicates. view more (2005-11-28)
Anti-malarials most effective in lupus patients genetically at risk of high levels of TNF-alpha
Anti-malarial drugs are most effective in people with lupus who are genetically predisposed to high levels of tumour necrosis factor alpha and low levels of the cytokine IL-10. view more (2006-02-13)
Study Demonstrates Safety of Oral Contraceptives in Women with Lupus
In a major study, women with either inactive or stable systemic lupus erythematosus (lupus) - a disease in which the body's immune system mistakenly attacks and damages healthy tissues of the skin, joints and internal organs - were able to take oral contraceptives without increased risk of flares, or periods of increased disease activity, that... view more... (2005-12-23)
Scripps research scientists find new genetic mutation that halts the development of lupus
The lupus-suppressing action is the result of what is known as a nonsense mutation of the Coronin-1A gene (Coro1a) required for the development of the disease. view more (2008-01-18)
Smokers with common autoimmune disorder at higher risk for skin damage
As if there weren't enough reasons to stop smoking, a team of researchers at the Research Institute of the McGill University Health Centre (RI-MUHC) have just found another. view more (2009-11-03)
Resetting epigenetic code could aid lupus patients
Researchers at Wake Forest University School of Medicine and the University of Virginia hope to reset part of the "epigenetic code" in lupus patients and thus improve treatment. view more (2005-11-08)
Potential autoimmunity-inducing cells found in healthy adults
It's not just patients with autoimmune diseases like lupus and rheumatoid arthritis (RA) that have self-attacking immune cells-healthy people have them too, according to a new report in the Journal of Experimental Medicine. view more (2008-12-22)
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