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Scripps scientists studying sepsis in mice find potential drug targets for deadly disease
"We have identified a key connection of signaling pathways in the cascade of events leading to sepsis. This defines a crucial point where the immune system spirals out of control to cause severe sepsis and where there is an opportunity for therapeutic intervention," says Scripps Research Professor Wolfram Ruf, who led the research with... view more... (2008-02-28)
Novel Discoveries Leading To Targeted Treatment Of Lymphatic Diseases
A gene responsible for lymphatic vessel formation Novel discoveries at the University of Helsinki, Finland, about the development of the lymphatic network may help researchers to better understand the mechanisms of cancer and its metastasis, and also diseases such as lymphedema, wound healing and inflammatory and autoimmune disorders. Lymphatic... view more... (2003-11-20)
Encouraging Progress Towards Early Identification Of Anthrax Inhalation
Authors of a research letter in this week's issue of THE LANCET outline progress in the ability to rapidly detect anthrax inhalation in the event of bioterrorist attacks. Limiting the effects of a bioterrorist anthrax attack will require the rapid and accurate recognition of symptoms among the earliest victims. Central to this will be the ability... view more... (2004-07-28)
First large-scale trial of genetically personalised treatment for breast cancer to start soon
Hamburg, Germany: The first large-scale independent trial to study the role of molecular tumour signatures in breast cancer will get underway in the coming year, scientists announced today (Friday March 19) at the 4th European Breast Cancer Conference. TRANS-BIG, a translational research network involving about 40 partners from... view more... (2004-03-17)
Cholesterol screening a cost-effective procedure to extend life in Hodgkin's disease survivors
Hodgkin's lymphoma survivors who have lipid screening every five years to detect high cholesterol will live a half year longer than patients who don't have the screening and the intervention is cost-effective. view more (2006-11-09)
Malaria parasite impairs key immune system cells
Plasmodium, the parasite responsible for malaria, impairs the ability of key cells of the immune system to trigger an efficient immune response. view more (2006-04-12)
Toronto researchers discover novel circulation in human eye, new glaucoma treatment target
Researchers at the University of Toronto, St. Michael's Hospital and Sunnybrook Health Sciences Centre have discovered a previously unidentified form of circulation within the human eye which may provide important new insights into glaucoma, a leading cause of blindness. view more (2009-10-06)
Study finds doxycycline effective against filariasis in Southeast Asia
Doxycycline alone is more effective against the most common form of filariasis in Southeast Asia than the standard treatment, with significantly fewer side effects, according to a new study published in the May 1 issue of Clinical Infectious Diseases and currently available online. view more (2008-04-10)
Bright tumors, dim prospects
It doesn't matter how small or large it is, if a cervical tumor glows brightly in a PET scan, it's apt to be more dangerous than dimmer tumors. That's the conclusion of a new study of cervical cancer patients at Washington University School of Medicine in St. Louis. view more (2007-09-14)
Surgery remans an option for advanced lung cancer
In recent years, oncologists have debated whether patients with a certain type of advanced lung cancer would benefit from surgery. view more (2009-07-27)
IU informatics researchers throttle notion of search engine dominance
Search engines are not biased toward popular Web sites, and may even be egalitarian in the way they direct traffic. view more (2006-08-08)
Cell study explains why younger people more at risk of vCJD
Specific cells within the immune system could help explain why younger people are more susceptible to variant CJD, scientists believe. view more (2009-10-14)
Tumors use enzyme to recruit regulatory T-cells and suppress immune response
One way tumors fly under the radar of the immune system is by using IDO, an enzyme used by fetuses to help avoid rejection, to recruit powerful regulatory T cells that turn down the immune response, researchers say. view more (2007-08-17)
Markers that can predict cancer spread could save women from unnecessary chemotherapy
Women with early breast cancer could avoid needless chemotherapy thanks to work carried out in Chicago on identifying biochemical markers which indicate whether or not cancer is likely to spread to other parts of the body, the 3rd European Breast Cancer Conference in Barcelona heard today (Saturday 23 March). Ruth Heimann, Associate Professor in... view more... (2002-03-21)
Antibiotics help combat dangerous tropical disease
The disease is triggered off by the bite of an infected mosquito: together with its anticoagulant the mosquito pumps threadworm larvae into its host's body. These gravitate towards the lymph nodes, where they grow into threadworms which may be up to ten centimetres long. view more (2005-06-27)
Optimal adjuvant radiation therapy associated with improved survival, meta-analysis shows
A new analysis of adjuvant radiation therapy in women with breast cancer following mastectomy is associated with better survival as measured at 10 years when appropriate doses and fields of radiation are used. view more (2006-01-04)
Can bench pressing reduce or prevent lymphedema symptoms in breast-cancer survivors?
In a novel research study to begin this week at the Abramson Cancer Center of the University of Pennsylvania, Kathryn Schmitz, PhD, MPH, Assistant Professor in Epidemiology, will help to determine the extent to which a slowly progressive program of strength-training exercises is safe for breast cancer survivors with and without symptoms of... view more... (2005-10-26)
What induce local recurrence of rectal carcinoma?
It is well known that local recurrence is the most important prognostic factor of rectal carcinoma. However, even after undergoing radical resection of primary tumors and lymph nodes, about 4%-50% of patients with rectal carcinoma were reportedly with local recurrence. view more (2008-09-22)
Short chromosomes put cancer cells in forced rest
A Johns Hopkins team has stopped in its tracks a form of blood cancer in mice by engineering and inactivating an enzyme, telomerase, thereby shortening the ends of chromosomes, called telomeres. view more (2007-04-26)
Protein predicts development of invasive breast cancer in women with DCIS, Penn study shows
Women with ductal carcinoma in situ (DCIS) who exhibit an overexpression of the protein HER2/neu have a six-fold increase in risk of invasive breast cancer. view more (2009-05-22)
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