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Lymphatic Vasculature Current Events | Lymphatic Vasculature News

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Venous origin of the mammalian lymphatic vasculature
In the October 1 issue of G&D, Dr. Guillermo Oliver (St. Jude Children's Research Hospital) and colleagues present new evidence to resolve a century-old debate over the origin of the mammalian lymphatic vasculature.   view more (2007-10-01)

Defective lymphatic vessels identified as a novel cause of obesity
Leaky lymphatic vessels are the leading cause of the adult onset obesity observed in a laboratory model developed by investigators at St. Jude Children's Research Hospital.   view more (2005-09-20)

St. Jude settles century-old debate on origin of mammalian network of lymphatic vessels
Investigators at St. Jude Children's Research Hospital settled a century-old debate on the origin of the mammalian lymphatic vasculature-the network of vessels and capillaries critical to various essential housekeeping functions in the body. The finding holds the promise for the development of new... view more (2007-10-04)

Breakthrough in understanding of hereditary disease of lymphatic vessels
(Helsinki, August 22nd) -- A study from the Ludwig Institute for Cancer Research (LICR) Affiliate Center at the University of Helsinki in Finland has shed light on the development of lymphatic vasculature and valves, and may help to develop better treatments for lymphedema. The disease, which... view more (2004-08-19)

University of Helsinki to coordinate two large EU research projects
The European Union has granted nearly 25 MEUR to two large-scale interdisciplinary research projects coordinated by the University of Helsinki. The project leaders are professor Raimo Tuominen from the UH's Faculty of Pharmacy and Academy professor Kari Alitalo from UH's Molecular and Cancer... view more (2004-08-24)

Novel Discoveries Leading To Targeted Treatment Of Lymphatic Diseases
A gene responsible for lymphatic vessel formation Novel discoveries at the University of Helsinki, Finland, about the development of the lymphatic network may help researchers to better understand the mechanisms of cancer and its metastasis, and also diseases such as lymphedema, wound healing and... view more (2003-11-20)

Targeting wolbachia, doxycycline reduces pathology of lymphatic filariasis
Lymphatic filariasis, a mosquito-borne tropical disease that afflicts 120 million people worldwide, can cause debilitating swelling of the legs and genital areas.   view more (2006-09-20)

A new significance of LVD and angiogenic MVD is identified in human primary SCRC
Lymphangiogenesis and angiogenesis are critical processes for tumor growth, invasion and metastasis. Angiogenesis has established its role in the development and progression of a variety of malignancies, playing a crucial role in the dissemination of the tumor cells.   view more (2008-01-17)

Yale study offers insight into possible cause of lymphoma
The immune system's powerful cellular mutation and repair processes appear to offer important clues as to how lymphatic cancer develops, Yale School of Medicine researchers report this week in Nature.   view more (2008-02-15)

St. Jude study shows temporary improvement of tumor blood flow can improve chemotherapy
A treatment for neuroblastoma that lands a one-two punch works best when the second punch is timed to take maximum advantage of the first one, according to results of studies at St. Jude Children's Research Hospital.   view more (2007-07-12)

Improving understanding of cell behaviour in breast cancer
The invasion and spread of cancer cells to other parts of the body, known as metastasis, is a principal cause of death in patients diagnosed with breast cancer.   view more (2008-07-16)

Study identifies another strategy for normalizing tumor blood supply
Manipulating levels of nitric oxide (NO), a gas involved in many biological processes, may improve the disorganized network of blood vessels supplying tumors, potentially improving the effectiveness of radiation and chemotherapy.   view more (2008-02-21)

Parasitic tropical diseases in the Americas, a legacy of slavery, can be eliminated
Although it has been speculated for more than a century that the slave trade was responsible for bringing many tropical diseases to the Americas, only recently has convincing evidence shown that lymphatic filariasis (elephantiasis), schistosomiasis, and onchocerciasis (river blindness) originated... view more (2007-11-07)

Improving understanding of cell behaviour in breast cancer
The invasion and spread of cancer cells to other parts of the body, known as metastasis, is a principal cause of death in patients diagnosed with breast cancer.   view more (2008-06-19)

Go with the flow: How cells use biological flows to signal and organize
An EPFL (Ecole Polytechnique Federale de Lausanne) team led by professor Melody Swartz has demonstrated for the first time that the presence of very slow biological flows affects the extracellular environment in ways that are critical for tissue formation and cell migration.   view more (2005-10-25)

Effective cancer immune therapy through order in the blood vessels
Immune therapies are considered very promising in cancer medicine: Tumor-fighting immune cells are supposed to invade tumor tissue and eliminate cancer cells right there.   view more (2008-04-22)

Neglected tropical diseases burden those overseas, but travelers also at risk
Though little known to most Americans, lymphatic filariasis, trachoma, leishmaniasis, onchocerciasis, schistosomiasis and other so-called neglected tropical diseases are responsible for severe health burdens, especially among the world's poorest people.   view more (2007-12-26)

Slight risk of leukaemia among UK nuclear test veterans "cannot be ruled out"
Nuclear test veterans are not at increased risk of premature death and developing cancer, overall, finds research in Occupational and Environmental Medicine. But the possibility that they may have a slightly increased risk of leukaemia, "cannot be ruled out," the authors conclude. The... view more (2003-02-21)

New paradigm for cell-specific gene delivery
Researchers from Northwestern University and Texas A & M University have discovered a new way to limit gene transfer and expression to specific tissues in animals.   view more (2008-06-23)

Cholesterol byproduct blocks heart health benefits of estrogen
New findings by UT Southwestern Medical Center researchers show that a byproduct of cholesterol metabolism interferes with the beneficial effects estrogen has on the cardiovascular system, providing a better understanding of the interplay between cholesterol and estrogen in heart disease.   view more (2007-09-17)

Malaria Parasites Develop in Lymph Nodes
In the first quantitative, real-time imaging study of the travels of the malaria parasite Plasmodium through mammalian tissue, researchers at the Pasteur Institute in Paris found the parasites developing in an unexpected place: the lymph nodes.   view more (2006-01-23)

Lymphedema risk greatly increased with boost of radiation to axillary nodes
The significant risk of developing lymphedema may outweigh the benefit of receiving an extra boost of radiation to lymph nodes possibly involved in early-stage breast cancer.   view more (2006-11-09)

Rapamycin shown to inhibit angiogenesis
Scientists have long known that the blood vessels of tumors differ markedly from normal blood vessels. Now, a research team led by scientists at Beth Israel Deaconess Medical Center (BIDMC) has identified a signaling pathway which, when activated, transforms otherwise healthy blood vessels into the... view more (2006-08-15)

Researchers identify ovarian cancer biomarkers
Researchers have identified markers unique to the cells of blood vessels running through ovarian tumors. The finding, while preliminary, could one day improve screening, diagnosis and treatment for this disease.   view more (2007-03-08)

Researchers identify ovarian cancer biomarkers
Researchers have identified markers unique to the cells of blood vessels running through ovarian tumors. The finding, while preliminary, could one day improve screening, diagnosis and treatment for this disease.   view more (2007-03-08)

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