Macrophages Current Events | Macrophages News | 3
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New strategy for protecting brain against Alzheimer's disease: Enhancing the innate immune system
The human body has its own defense against brain aging: the innate immune system, which helps to clean the brain of amyloid-beta waste products. However, UCLA researchers discovered that some patients with Alzheimer's disease have an immune defect making it difficult to clean away these wastes. view more (2005-06-10)
Inflammatory reaction drives hormone resistance in cancer, study suggests
In the February 10, 2006 Cell, researchers report new evidence to explain why prostate cancer and other hormone-dependent cancers may become resistant to hormone therapies. view more (2006-02-10)
New insight in the fight against the Leishmania parasite
Professor Albert Descoteaux's team at Centre INRS - Institut Armand-Frappier has gained a better understanding of how the Leishmania donovani parasite manages to outsmart the human immune system and proliferate with impunity, causing visceral leishmaniasis, a chronic infection that is potentially fatal if left untreated. view more (2009-10-26)
Researchers link master regulator of innate immunity to the hypoxic response
Survival of all animals depends on their ability to withstand microbial infections and adapt to fluctuations in oxygen concentrations. view more (2008-04-24)
St. Jude finds link between cellular defense processes, showing how cancer cells survive
St. Jude Children's Research Hospital investigators have discovered that immune system cells that engulf and destroy germs in the body enlist help for this task from a common housekeeping mechanism that most cells use to keep their interiors healthy, a finding that is likely to help researchers understand how the body defends itself against... view more... (2007-12-20)
UQ scientists break new ground in fight against infection & chronic disease
University of Queensland (UQ) researchers are on track to develop new treatments for acute infections, chronic inflammatory diseases and cancer. view more (2005-11-30)
Cytokine resistance contributes to pathology of type 2 diabetes
In a study appearing this month in the Journal of Immunology, researchers at the University of Illinois describe how an impaired anti-inflammatory response plays a role in the pathology of type 2 diabetes. view more (2007-06-18)
Two Genes Are Important Key to Regulating Immune Response
A research team at Weill Cornell Medical College in New York City has identified two genes that may be crucial to the production of an immune system cytokine called interleukin-10 (IL-10). view more (2008-01-02)
Nanotechnology shows early promise to treat cardiovascular disease
A new tactic in the battle against cardiovascular disease - employing nanoengineered molecules called "nanolipoblockers" as frontline infantry against harmful cholesterol - is showing promise in early laboratory studies. view more (2006-05-11)
Dominant cholesterol-metabolism ideas challenged by new research
A team of researchers investigating cholesterol and lipid transport has performed experiments that cast serious doubt on the dominant hypothesis of how the body rids its cells of "bad" cholesterol (LDL) and increases "good" cholesterol (HDL). view more (2007-08-16)
Key study offers hope to patients with lung and joint disease
People who suffer from inflammatory conditions such as chronic diseases of the lung, joints and other organs could benefit from a new discovery by scientists at the University of Edinburgh. view more (2006-09-05)
Gene transfer using mutant form of good cholesterol cuts vascular plaque and inflammation
Transfer of a gene that produces a mutant form of good cholesterol provides significantly better anti-plaque and anti-inflammation benefits than therapy using the "normal" HDL gene. view more (2006-09-29)
MIT uncovers key blood protein
Scientists working in the only lab at MIT doing hematology research have uncovered a protein that plays a key role in the recycling of iron from blood. view more (2007-10-12)
Major discovery opens door to leishmania treatment
Leishmania is a deadly parasitic disease that affects over 12 million people worldwide, with more than 2 million new cases reported every year. view more (2009-10-07)
Catching the blood cell bus gives fatal yeast infection a clean getaway
Yeast fungus cells that kill thousands of AIDS patients every year escape detection by our bodies' defences by hiding inside our own defence cells, and hitch a ride through our systems before attacking and spreading, scientists heard today (Tuesday 9 September 2008) at the Society for General Microbiology's Autumn meeting being held this week at... view more... (2008-09-09)
Research uncovers signaling pathways related to brain-immune system links
New research on signaling pathways in immune cells bolsters evidence of connections between the central nervous system and the immune system. view more (2006-05-16)
Stripping leukemia-initiating cells of their 'invisibility cloak'
Two new studies reveal a way to increase the body's appetite for gobbling up the cancer stem cells responsible for acute myeloid leukemia (AML), a form of cancer with a particularly poor survival rate. view more (2009-07-24)
Legionnaire's bacterial proteins work together to survive
Proteins within the bacteria that cause Legionnaire's disease can kidnap their own molecular "coffin" and carry it to a safe place within the cell, ensuring their survival, Yale School of Medicine researchers report in Nature Wednesday. view more (2007-10-24)
Yale researchers discover Legionnaire microbe's tricks
Yale University researchers have shed new light how bacteria like the ones that cause Legionnaires' disease and Q-fever raise such havoc in human patients. view more (2008-06-20)
Human testis harbors HIV-1 in resident immune cells
Researchers have demonstrated HIV replication within resident immune cells of the testis, providing an explanation for the persistence of virus in semen even after effective highly active antiretroviral therapy. view more (2006-11-27)
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