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New discoveries from Harvard and Baylor get to the heart of cardiovascular disease
Even if you eat right and exercise regularly, chances are high that you'll still die of a heart attack or stroke. But thanks to new findings by researchers from Harvard and Baylor, the odds may finally shift in your favor. view more (2008-06-19)
Friend or foe? How the body's clot-busting system speeds up atherosclerosis
Sometimes it's hard to tell friends from foes, biologically speaking. Naturally produced in the body, urokinase plasminogen activator and plasminogen interact to break up blood clots and recruit clean-up cells to clear away debris related to inflammation. In fact, urokinase manufactured as a drug effectively clears clogged arteries by generating... view more... (2008-10-31)
What separates dangerous blood vessel plaques from benign ones
Researchers say they have evidence to explain what separates your average blood vessel plaque from those that are at high risk for triggering the development of dangerous-even fatal-blood clots. view more (2009-05-06)
Compound in broccoli could boost immune system, says new study
A compound found in broccoli and related vegetables may have more health-boosting tricks up its sleeves, according to a new study led by researchers at the University of California, Berkeley. view more (2007-08-21)
Sexual differences in immune response appear at puberty
The differences in the male and female immune responses, which make females more prone to autoimmune disease and males more subject to infections, are established during puberty. view more (2006-02-22)
What is the function of NOD2 in colonic epithelial cells?
NOD2 is a cytosolic pattern recognition receptor similar in structure and function to Toll like receptors (TLRs). It can recognize and respond to a component found in the cell wall of bacteria, muramyl dipeptide (MDP), and has been shown to play an important role in the innate immune response of macrophages to bacterial infections. view more (2008-10-23)
Combining multiple treatments improves multiple sclerosis therapy
Multiple sclerosis (MS) is an inflammatory autoimmune disease of the central nervous system (CNS) in which white blood cells known as lymphocytes attack the myelin insulation on nerves in the spinal cord and brain. view more (2006-03-17)
Discovery in the evolution of the immune system absorbing cells
Led by Dr J Oriol Sunyer, of the Faculty of Veterinary Medicine at the University of Pennsylvania, and formed by researchers from Philadelphia, St Louis and Idaho (USA) and by Dr Lluís Tort of the Universitat Autònoma de Barcelona, the group has been able to show that B cells in fish as well as in amphibians are capable of strong phagocytosis... view more... (2006-10-05)
Sperm may play leading role in spreading HIV
Sperm, and not just the fluid it bathes in, can transmit HIV to macrophages, T cells, and dendritic cells (DCs), report a team led by Ana Ceballos at the University of Buenos Aires in Argentina. view more (2009-10-26)
A novel method of isolating high quality RNA from Kupffer cells
Kupffer cells, resident tissue macrophages that line the liver sinusoids, play a key role in modulating inflammation in a number of experimental models of liver injury. view more (2009-04-17)
Therapy For Mice With Prion Disease Could Offer Benefit To Human Beings With CJD
Authors of a fast-track research letter in this week's issue of THE LANCET describe a therapeutic treatment which increased the survival time for mice with prion disease. These results could represent a new approach to treating CJD in human beings. The lack of an immune response to prions-the infectious proteins that cause scrapie, bovine... view more... (2002-07-17)
Scientists find how bacteria in cows milk may cause Crohn's disease
Scientists at the University of Liverpool have found how a bacterium, known to cause illness in cattle, may cause Crohn's disease in humans. view more (2007-12-11)
Scientists glimpse a rare human antibody which protects against AIDS
Scientists have obtained their first detailed glimpse of a rare antibody, called b12, which is capable of inactivating many different strains of HIV, the virus which causes AIDS. A crystal structure of b12 has been determined by scientists working at The Scripps Research Institute, California, and the Glycobiology Institute at Oxford University,... view more... (2001-08-08)
Unusual carbohydrate structure in the cell walls of tuberculosis bacteria-a new point of attack for drugs?
Even though we have lost much of our fear of tuberculosis in the industrialized countries, according to the WHO about 2 mio. people worldwide die each year of this infectious disease. Researchers at the University of Leeds have now discovered a carbohydrate with an unusual structure in the cell walls of Mycobacterium tuberculosis, the bacterium... view more... (2004-07-27)
Researchers capture bacterial infection on film
Whilst most studies of bacterial infection are done after the death of the infected organism, this system developed by scientists at the University of Bath and University of Exeter is the first to follow the progress of infection in real-time with living organisms. view more (2009-07-28)
Why could ethyl pyruvate attenuate severe acute pancreatitis?
Excessive activation of inflammatory mediator cascade during SAP is a major cause of distant organ injury and the high mortality. view more (2008-10-13)
Cancer-causing gut bacteria exposed
Normal gut bacteria are thought to be involved in colon cancer but the exact mechanisms have remained unknown. Now, scientists from the USA have discovered that a molecule produced by a common gut bacterium activates signalling pathways that are associated with cancer cells. view more (2008-09-22)
New therapeutic targets in the treatment of ulcerative colitis
Social, environmental and dietary changes are associated with the changes of disease spectrum in a country. Ulcerative colitis has become a commonly seen disease in China, probably due to extensive consumption of Western foods in recent years. view more (2007-11-14)
Leishmaniasis parasites evade death by exploiting the immune response to sand fly bites
Cutaneous leishmaniasis, a disease characterized by painful skin ulcers, occurs when the parasite Leishmania major, or a related species, is transmitted to a mammalian host by the bite of an infected sand fly. view more (2008-08-15)
Skin care: new research into scar-free healing
New research from the University of Bristol shows that by suppressing one of the genes that normally switches on in wound cells, wounds can heal faster and reduce scarring. This has major implications not just for wound victims but also for people who suffer organ tissue damage through illness or abdominal surgery. view more (2008-01-21)
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