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Venous origin of the mammalian lymphatic vasculature
In the October 1 issue of G&D, Dr. Guillermo Oliver (St. Jude Children's Research Hospital) and colleagues present new evidence to resolve a century-old debate over the origin of the mammalian lymphatic vasculature. view more (2007-10-01)
CHECKING HOW CELLS GROW: New research dismisses a widely held assumption about cell growth
Research published today in Journal of Biology challenges an assumption about cell growth that underpins modern cellular biology. Ian Conlon and Martin Raff, of University College London, show that mammalian cells do not regulate their size in the way scientists have assumed they do since the 1970s. Conlon and Raff conducted a series of... view more... (2003-04-23)
Mammalian neurogenesis breaks into the most static brain region
ifteen years ago, the discovery of adult neurogenesis (the production of new neurons) in the highly static, non-renewable mammalian brain was a breakthrough in neuroscience. view more (2008-06-04)
Rong Li Lab demonstrates the process of mammalian egg maturation
he Rong Li lab team has answered an important question about how mammalian eggs undergo maturation through an intricate process of asymmetric cell division. The team discovered a novel pathway by which chromatin exerts command on the cell membrane to produce a specialized machinery used for cell division. view more (2007-02-06)
Oliguridylation-mediated histone mRNA decay
In the January 1st issue of G&D, Drs. Thomas Mullen and William Marzluff (UNC Chapel Hill) lend new insight into the degradation of mammalian histone mRNA. view more (2008-01-02)
Building brains: Mammalian-like neurogenesis in fruit flies
A new way of generating brain cells has been uncovered in Drosophila. The findings, published this week in the online open access journal Neural Development, reveal that this novel mode of neurogenesis is very similar to that seen in mammalian brains, suggesting that key aspects of neural development could be shared by insects and mammals. view more (2008-02-19)
Common algae helps illustrate mammalian brain electrical circuitry
Mice whose brain cells respond to a flash of light are providing insight into the complexities of the sense of smell and may ultimately yield a better understanding of how the human brain works. view more (2007-04-19)
Scientists discover stage at which an embryonic cell is fated to become a stem cell
Cambridge scientists have discovered the stage at which some of the cells of a fertilised mammalian egg are fated to develop into stem cells and why this occurs. view more (2007-01-11)
The evolutionary foundation of genomic imprinting in lower vertebrates
A Chinese scientist group working in College of Life Science, Zhejiang University, has shown that, as mammalian Igf2 CpG island, goldfish Igf2 CpG island has a parental differentially methylated region (DMR). view more (2009-05-18)
Dying of excitement
For neurons, overexcitement is deadly. To avoid this, brain cells must sop up unneeded neurotransmitters from the synapse through membrane-bound transporters. If these transporters fail, neurons and other brain cells get excited to death- a phenomenon that may contribute to brain damage during stroke and Alzheimer's disease. view more (2006-03-06)
Nanowire arrays can detect signals along individual neurons
Opening a whole new interface between nanotechnology and neuroscience, scientists at Harvard University have used slender silicon nanowires to detect, stimulate, and inhibit nerve signals along the axons and dendrites of live mammalian neurons. view more (2006-08-25)
Fly with brain tumor may shed light on cancer causing genes
A study showing how the expression of genes changes when the brain tissue of fruit flies becomes cancerous is published this week in BMC Genomics. As the function of many of these genes is conserved across evolution, the researchers expect their results will help us to understand why human brain tumors develop. The causes of brain tumor... view more... (2004-04-14)
Gene that magnetically labels cells shows potential as imaging tool
Mammalian cells can produce tiny magnetic nuggets after the introduction of a single gene from bacteria, scientists have found. The gene MagA could become a valuable tool for tracking cells' movement through the body via magnetic resonance imaging (MRI), says Xiaoping Hu, PhD, professor of biomedical engineering at Emory University and the Georgia... view more... (2008-06-04)
Using insects to test for drug safety
Insects, such as some moths and fruit flies, react to microbial infection in the same way as mammals and so can be used to test the efficiency of new drugs, thereby reducing the need for animal testing. view more (2009-09-08)
EURYI project to understand how the brain wires during embryogenesis
One of the great questions of neurobiology, how the brain is built up during embryonic development, could be resolved by a young French scientist in an award winning project organised by the European Science Foundation (ESF) and the European Heads of Research Councils (EuroHORCS). view more (2007-09-24)
Why are lions not as big as elephants?
Carnivores are some of the widest ranging terrestrial mammals for their size, and this affects their energy intake and needs. view more (2007-01-16)
Brittle prions are more infectious
Brittleness is often seen as a sign of fragility. But in the case of infectious proteins called prions, brittleness makes for a tougher, more menacing pathogen. view more (2006-06-29)
Groundbreaking study helps explain why preemie brains improve over time
Infants born prematurely and with hypoxia-inadequate oxygen to the blood-are able to recover some cells, volume and weight in the brain after oxygen supply is restored, Yale School of Medicine researchers report in Experimental Neurology. view more (2005-06-28)
Conserved gene expression reveals our 'inner fish'
A study of gene expression in chickens, frogs, pufferfish, mice and people has revealed surprising similarities in several key tissues. view more (2009-04-16)
Molecular mechanism provides intra-cellular traffic signal
Researchers at the University of Illinois at Chicago have found that intra-cellular trafficking is tightly coordinated for maximum flow through cellular compartments - much as vehicles on a crowded road are allowed to pass quickly through a succession of green traffic lights. view more (2006-10-18)
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