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Temperature sensing by the circadian clock
In the September 1 issue of G&D, Dr. Michael Brunner and colleagues have uncovered the molecular mechanism whereby temperature affects circadian patterns in the fungus Neurospora.   view more (2005-08-17)

Stopping dangerous trailer skids
Slippery winter roads make it easy for trailers trucks to skid. Roads with deep grooves or curves, evasive maneuvers, and sudden braking all raise the risk of a trailer skid.   view more (2005-04-21)

Effect of microstructure on the coercivity of HDDR Nd-Fe-B permanent magnetic alloy
The School of Physics, Shandong University, has shown that the coercivity mechanism of HDDR Nd-Fe-B permanent magnetic alloy is greatly related to its microstructure defect at the grain boundary. The investigation can provide a clear understanding of coercivity mechanism, and hence will be reported... view more (2008-07-24)

Rare cell prevents rampant brain activity
One of the mysteries of the brain is how it avoids ending up in a state of chaos, something which happens only on exceptional occasions, when it can lead to epileptic fits. Scientists at Karolinska Institutet have now uncovered a new mechanism controlling how the brain keeps its neuronal activity... view more (2007-03-05)

Pneumatosis cystoids intestinalis after fluorouracil chemotherapy
The mechanism of pneumatosis cystoids intestinalis (PCI) is unclear. The mechanical and bacterial factors are most predominant causes of PCI.   view more (2008-09-18)

Researchers discover cell's 'quality control' mechanism
Researchers in Japan and Canada have discovered a key component of the quality control mechanism that operates inside human cells - sometimes too well. The breakthrough has significant implications for the development of new treatments for cystic fibrosis (CF) and some other hereditary diseases,... view more (2008-07-30)

Treating SSRI-Resistant Depression
When your antidepressant medication does not work, should you switch to a different medication from the same class or should you try an antidepressant medication that has a different mechanism of action? This is the question asked by researchers in a new report scheduled for publication in... view more (2008-03-26)

Double identities lie behind chromosome disorders
Chromosome disorders in sex cells cause infertility, miscarriage and irregular numbers of chromosomes (aneuploidy) in neonates. A new study from Karolinska Institutet published in the scientific journal Nature Genetics shows how chromosome disorders can arise when sex cells are formed.   view more (2007-07-09)

Breakthrough in understanding of blood vessel inflammation
Medical scientists at the University of Leicester have announced a breakthrough in their understanding of blood vessel inflammation - a serious condition which underlies health problems like organ failure in sepsis, the ability to recover from burns, and transplant rejection. The team in the... view more (2004-01-19)

Contribution of cholesterol transporter to vascular disease
Low-density lipoprotein (LDL), a transporter of cholesterol, may also contribute to vascular diseases by a previously unidentified mechanism, according to a report published online this week in EMBO reports.   view more (2007-10-26)

Novel findings about neovessel formation
The main role in new findings about neovessel formation is played by a protein called tissue factor. This factor turns out to have both a stimulatory function and an inhibitory function in the generation of blood vessels. Normally these two functions neutralize each other, but in diseases like... view more (2004-05-10)

Compound has potential for new class of AIDS drugs
Researchers have developed what they believe is the first new mechanism in nearly 20 years for inhibiting a common target used to treat all HIV patients, which could eventually lead to a new class of AIDS drugs.   view more (2008-05-15)

Electronic Handbrake
The adjudication panel of the IV Accenture Prize for the Best Graduate Thesis at the Bilbao School of Technical Engineering has been awarded to Grzegorz Breczewski, a 24-year-old graduate student who has developed a project known as "electronic brake for stationary mode" and which is a... view more (2004-06-16)

New research promises cure by mouth
A researcher at Aston University in Birmingham has become the first in the UK to investigate a new type of vaccination delivery that could revolutionise how we are protected against diseases including flu, hepatitis and, most excitingly, cancer. Dr Yvonne Perrie from the School of Life & Health... view more (2002-12-02)

Non-coding RNAs help silence the mammalian transcription
Dr. Shirley Tilghman and colleagues (Princeton University) lend new insight into the mechanism of genomic imprinting, demonstrating a necessary role for a non-coding RNA transcript in the silencing of an imprinted gene cluster in mice.   view more (2006-05-15)

Free Electricity Market Could Lead To Power Shortages
Because the free electricity market in its current form does not lead to sufficient investments in power plants, the price of electricity could become very high and a shortages could occur.   view more (2004-06-22)

Immunologists find better way to boost the immune system
Immunologists have discovered how to manipulate the immune system to increase its power and protect the body from successive viral infections.   view more (2008-01-23)

Genome circularization and RNA virus replication
As featured on the cover of the August 15th issue of G&D, an Argentinian research team, led by Dr. Andrea Gamarnik, report on their recent discovery of a novel mechanism of dengue virus replication.   view more (2006-08-01)

Discovery of a mechanism that regulates cell movement
A study performed by researchers at the Institute for Research in Biomedicine (IRB Barcelona), in collaboration with researchers at the Instituto de Biología Molecular of the CSIC, reveal a mechanism that controls the movement of cells in a tissue by regulating cell adhesion.   view more (2008-07-21)

Simulations help explain fast water transport in nanotubes
By discovering the physical mechanism behind the rapid transport of water in carbon nanotubes, scientists at the University of Illinois have moved a step closer to ultra-efficient, next-generation nanofluidic devices for drug delivery, water purification and nano-manufacturing.    view more (2008-09-17)

Radicals Shake Up Molecules in a Tug o' War
Until now, it was commonly thought that colliding molecules get the shakes as the result of energy transfer solely from the smashing of the molecules, but some new research adds a second means by which colliding molecules become vibrationally excited--it is being called the "Tug o' War... view more (2008-07-07)

Bread mold may hold secret to eliminating disease-causing genes
When most people discover mold on their bread, they immediately throw it out. Others see a world of possibilities in the tiny fungus. A University of Missouri scientist, along with a collaborative research team, has examined a new mechanism in the reproductive cycle of a certain species of mold.   view more (2008-05-09)

Natural gas inhabited by unusual specialists
A German-American research team of biologists and geochemists has discovered hitherto unknown anaerobic bacteria in marine sediments which need only propane or butane for growth.   view more (2007-09-24)

Bizarre bug wears host's skin
Oxford scientists have discovered a particularly macabre method one parasite (Strepsiptera) has for disguising itself in its insect host: it wraps itself in a piece of the host's own body tissue. In this way the strepsipteran masquerades as 'self', and is protected from the insect's immune system.... view more (2003-06-03)

Deficient regulators in the immune system responsible for type 1 diabetes
The main regulators of the immune system, called CD4+Treg cells, are thought to be highly involved in a large range of immune diseases.   view more (2008-01-25)
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