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Bug factories for drugs: quality control holds key to quantity
Tiny types of soil bugs already make many of the products we use in washing detergents, foods, and waste treatment, but scientists now hope that similar bacteria will also make the vaccines and drugs of the future, according to new research presented today (Tuesday, 07 September 2004) at the... view more (2004-08-23)

An effective strategy for inhibition of cirrhosis
In China, the incidence of liver cirrhosis is still high, although new therapeutic approaches have recently been proposed, there is no established therapy for liver fibrosis, and Authors investigated the prevention effects of Chinese Medicine Qianggan-Rongxian Soup on liver fibrosis induced by DMN... view more (2008-09-25)

Scientists shine new light on inflammatory diseases
Investigators at Hospital for Special Surgery have identified a new mechanism involved in the pathogenesis of inflammatory diseases such as rheumatoid arthritis.   view more (2008-03-17)

Origins of Life
Were the first macromolecules created on a primitive beach?   view more (2002-06-19)

Molecular mechanism provides intra-cellular traffic signal
Researchers at the University of Illinois at Chicago have found that intra-cellular trafficking is tightly coordinated for maximum flow through cellular compartments - much as vehicles on a crowded road are allowed to pass quickly through a succession of green traffic lights.   view more (2006-10-18)

Cooling analgesia harnessed to relieve chronic pain
By experimentally activating a special protein involved in mediating sensations of coolness, researchers have made a breakthrough in understanding how the body's nervous system can be stimulated to relieve chronic pain.   view more (2006-08-22)

Novel virus entry mechanism could lead to new drugs against poxviruses
Research published in the Proceedings of the National Academy of Sciences on 11 April describes how the Imperial College London team discovered the mechanism allowing Vaccinia virus to shed its outer lipid membrane and enter cells. The mechanism is unique in virology and paves the way for... view more (2006-04-12)

Study reveals body's defense mechanism worsens asthma symptoms
MUHC scientists have discovered that our body's own defense mechanism causes some of the most serious asthma symptoms.   view more (2005-08-12)

Tissue regeneration operates differently than expected
Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany, in co-operation with colleagues from Martin Luther University in Halle-Wittenberg, have now shown that skeletal muscle tissue can fuse with adult stem cells, via a mechanism based on the participation of... view more (2005-08-05)

Study suggests new treatments for Huntington's disease
Working with fruit flies, researchers have discovered a new mechanism by which the abnormal protein in Huntington's disease causes neurodegeneration.   view more (2008-01-10)

Genomics researchers discover protein deficit that causes drug toxicity
Mayo Clinic researchers have discovered an inherited structural mechanism that can make drugs for some diseases toxic for some patients. The mechanism decreases a protein and in turn causes certain individuals to metabolize thiopurine drugs differently.   view more (2005-07-11)

House dust mite project aims to reduce asthma
A promising new way of controlling the mites that can cause asthma and other allergies is now under development. It could lead to dramatic progress in preventing these conditions and reduce the estimated £700 million a year spent in the UK on treating them. The technique uses a computer model... view more (2004-02-05)

Researchers Uncover a Novel Mechanism of Action of a Potential New Drug for the Treatment of Multiple Sclerosis
Virginia Commonwealth University researchers have identified a unique mechanism of action of a new drug that shows great promise for the treatment of multiple sclerosis.   view more (2006-10-12)

Strain has major effect on high-temp superconductors
Just a little mechanical strain can cause a large drop in the maximum current carried by high-temperature superconductors, according to novel measurements carried out by the National Institute of Standards and Technology (NIST).   view more (2007-02-16)

Endogenous cannabinoids linked to fetal brain damage imposed by maternal cannabis use
A critical step in brain development is governed by endogenous cannabinoids, 'the brain's own marijuana'.   view more (2007-05-25)

Rong Li Lab probes mechanism of asymmetry in meiotic cell division
The Stowers Institute's Rong Li Lab has characterized a mechanism that allows for asymmetrical cell division during meiosis in oocytes. By tracking chromosome movement in live mouse oocytes, the team discovered that chromosomes can recruit to their vicinity a protein called formin-2.   view more (2008-10-08)

Linking DNA and histone methylation
In the May 15th issue of G&D, Dr. Michael Carey (UCLA's Jonsson Comprehensive Cancer Center) and colleagues lend new insight into the mechanism of epigenetic silencing of euchromatic genes.   view more (2007-04-30)

Discovery of key inflammation mechanism in COPD could lead to new treatments
An international team of researchers has identified a mechanism which increases lung inflammation, making Chronic Obstructive Pulmonary Disorder (COPD) more severe, and potentially points towards new treatments.   view more (2005-05-10)

A more complete study of the Solar System
The Basque company SENER has been contracted by the European Space Agency (ESA) to prepare a technologies programme for the GAIA astronomy mission. The specifications of this satellite include an 11-metre diameter parasol which unfolds after being put into orbit, giving thermal stability in a... view more (2004-02-05)

Changing the rings: a key finding for magnetics design
Researchers at the National Institute of Standards and Technology's Center for Nanoscale Science and Technology (CNST) have done the first theoretical determination of the dominant damping mechanism that settles down excited magnetic states-"ringing" in physics parlance-in some key metals.   view more (2007-08-06)

Jefferson researchers uncover new way nature turns genes on and off
Peering deep within the cells of fruit flies, developmental biologists at the Kimmel Cancer Center at Thomas Jefferson University in Philadelphia may have discovered a new way that genes are turned on and off during development.   view more (2006-12-28)

Novel regulatory mechanism identified for key tumor suppressor p53
Collaborating scientists from The Wistar Institute in Philadelphia and The Vienna Biocenter in Austria have identified a novel mechanism involved in normal repression of the p53 protein, perhaps the single most important molecule for the control of cancer in humans.   view more (2006-11-16)

Nanosecond-scale release of stinging jellyfish nematocysts
By using an electronic ultra-high-speed camera, researchers have characterized the explosive discharge of stinging jellyfish nematocytes and show that this event represents one of the fastest cellular processes in nature.   view more (2006-05-09)

KGI professor contributes new insights on 'jumping genes'
Keck Graduate Institute (KGI) today announced that Dr. Animesh Ray, KGI professor and director of KGI's PhD program, has published a paper in the international online journal PLoS ONE that sheds new light on the evolution of moveable genetic elements, or "jumping genes."   view more (2007-10-09)

Researchers uncover new mechanism of tumor suppressor
Researchers from the University of Colorado-Denver and Health Sciences Center and Stanford University have discovered a molecular mechanism that explains how cells respond to DNA damage and other acute stresses, and if disrupted can cause cancer.   view more (2006-05-22)
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