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How vitamin C stops the big 'C'
Nearly 30 years after Nobel laureate Linus Pauling famously and controversially suggested that vitamin C supplements can prevent cancer, a team of Johns Hopkins scientists have shown that in mice at least, vitamin C - and potentially other antioxidants - can indeed inhibit the growth of some tumors... view more (2007-09-11)

Research shows certain metabolites responsible for initiating breast and prostate cancer
Cancer researchers have discovered that metabolites of natural estrogens can react with deoxyribonucleic acid (DNA) to cause specific damage that initiates the series of events leading to breast, prostate and other human cancers.   view more (2006-03-29)

Yale scientists visualize the machinery of mRNA splicing
Recent research at Yale provided a glimpse of the ancient mechanism that helped diversify our genomes; it illuminated a relationship between gene processing in humans and the most primitive organisms by creating the first crystal structure of a crucial self-splicing region of RNA.   view more (2008-04-07)

Key to virulence protein entry into host cells discovered
Researchers from the Virginia Bioinformatics Institute (VBI) at Virginia Tech have identified the region of a large family of virulence proteins in oomycete plant pathogens that enables the proteins to enter the cells of their hosts.   view more (2008-08-05)

HHMI Undergraduate Researcher Turns Up the Heat on Hibernation
If doctors could put people in hibernation and pull them out at will, scientists think they could minimize damage from strokes, help recipients' bodies accept transplanted organs, perhaps even enable astronauts to travel in suspended animation until reaching distant destinations.   view more (2006-02-01)

Structure of key enzyme in plague bacterium found
Researchers at the National Institute of Standards and Technology (NIST) have solved the structure of a key enzyme from the bacterium responsible for plague, finding that it has a highly unusual configuration. The results may shed light both on how the bacterium kills and on fundamental cell... view more (2006-08-21)

Carnegie Mellon develops computer model to study cell membrane dynamics
A cell constantly remodels its fluid membranes to carry out critical tasks, such as recognizing other cells, getting nutrients or sorting proteins.   view more (2008-04-09)

Scientists unlock secret of what makes plants flower
The study reveals the likely mechanism by which the Arabidopsis plant flowers in response to changes in day length. Earlier research had shown that plants' leaves perceived seasonal changes in day length, which triggers a long-distance signal to travel through the plant's vascular system from the... view more (2007-04-20)

Immunity in social amoeba suggests ancient beginnings
Finding an immune system in the social amoeba (Dictyostelium discoideum) is not only surprising but it also may prove a clue as to what is necessary for an organism to become multicellular, said the Baylor College of Medicine researcher who led the research that appears today in the journal Science.   view more (2007-08-03)

Enzyme action creates protein linked to Alzheimer's disease
Researchers at UT Southwestern Medical Center have defined a key step in the production of beta-amyloid, a short protein that is thought to be responsible for the development of Alzheimer's disease.   view more (2005-08-15)

Drug triggers body's mechanism to reverse aging effect on memory process
A drug made to enhance memory appears to trigger a natural mechanism in the brain that fully reverses age-related memory loss, even after the drug itself has left the body, according to researchers at UC Irvine.   view more (2006-07-28)

Protein Plays Critical Role in Heart Failure in Both the Heart and Adrenal Gland
A protein that plays an important regulatory role in heart failure in the heart also exerts powerful effects on the adrenal gland, Jefferson Medical College researchers have found.   view more (2005-11-16)

Researchers at IRB Barcelona discover one of the mechanisms that prevents the spread of colon cancer
The first step in the development of colon cancer is the formation of benign tumours, called adenomas, in the intestine. Over time, these tumours may progress to produce colon cancer if they undergo a series of mutations and genetic alterations.   view more (2007-10-01)

A single mechanism for hypertension, insulin resistance and immune suppression
Many of the 75 million Americans with essential hypertension also develop diabetes and other complications in addition to their high blood pressure, and researchers have discovered a common molecular mechanism in a strain of rat that explains why such metabolic disorders arise together in mammals.   view more (2008-06-30)

New mechanism for cardiac arrhythmia discovered
It has long been thought that virus infections can cause cardiac arrhythmia. But why has not been understood. Ulrike Lisewski, Dr. Yu Shi, Michael Radke and Professor Michael Gotthardt of the Max Delbrück Center for Molecular Medicine (MDC) Berlin-Buch, Germany, have now discovered the... view more (2008-09-18)

Glycoprotein hormone receptors
We have aspired at understanding and further dissecting the molecular mechanism of activation of the Glycoprotein hormone receptors (GpHr), members of the G protein coupled receptor (GPCR) superfamily.   view more (2006-01-17)

New clues to how major weight-loss drugs work
Some of the most important weight-loss drugs work by enhancing the effect of the brain chemical serotonin. These include sibutramine (trade name Meridia) and fenfluramine, which was recalled after the combination with dexfenfluramine, called fen-phen, was linked to potentially fatal heart valve... view more (2006-07-20)

A new treatment for T-cell acute lymphoblastic leukaemia?
IL-7, a hormone-like protein involved in cell-cell interaction, has been associated with increased survival and expansion of T-cell acute lymphoblastic leukaemia (T-ALL). Now, in the latest issue of the Journal of Experimental Medicine, a team of scientists, not only confirms the essential role of... view more (2004-09-09)

Case closed: MIT gumshoes solve
Hey kids! Try this at home. Pour clean water onto a small plate. Wait for all the ripples to stop.   view more (2007-07-18)

Scientists unravel the molecular basis of monarch butterfly migration
Since its discovery, the annual migration of eastern North American monarch butterfly has captivated the human imagination and spirit. That millions of butterflies annually fly up to 2000 miles to reach a cluster of pine groves in central Mexico comprising just 70 square miles is for many an... view more (2008-01-09)

A good connection - A New Directory of European Innovation
Innovation is all about connections. Finding the support or information you need, or the person with the experience that matches your requirements, is the first step towards introducing change. The new Directory of European Innovation is intended to accelerate that process. It covers the principal... view more (2002-11-04)

Textbook explanation of mRNA translation may need rethinking
Our understanding of how messenger RNAs are translated into proteins is challenged by new research published today in the Open Access journal Journal of Biology.   view more (2005-06-27)

Copper damages protein that defends against Alzheimer's
Copper can damage a molecule that escorts out of the brain a substance called amyloid beta that builds up in toxic quantities in the brains of people with Alzheimer's disease.   view more (2007-11-07)

Cause of diabetes-related erectile dysfunction is clarified by Johns Hopkins researchers
A new study from the Brady Urological Institute at Johns Hopkins suggests an over-supply of a simple blood sugar could be a major cause of erectile dysfunction in diabetic men.   view more (2005-08-10)

Fight against hay fever and other allergies helped by new immune system discovery
A mechanism which can lead to hay fever and other allergic reactions, by preventing the immune system from regulating itself properly, has been discovered by scientists.   view more (2007-12-27)
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