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New brain tumor model developed
A collaboration of researchers, led by Dr. Martine Roussel (St. Jude Children's Research Hospital), has developed a novel mouse model of medulloblastoma - the most prevalent malignant pediatric brain tumor.   view more (2005-10-31)

Prenatal vitamins may reduce risk of brain tumors in children
Women who take multivitamins early in pregnancy may reduce the risk that their child will develop some types of brain tumors.   view more (2006-09-21)

Improved treatment raises medulloblastoma survival rate
A team of investigators led by St. Jude Children's Research Hospital has announced that improvements in the treatment of the childhood brain cancer medulloblastoma have significantly increased the rate of survival of children with this disease.   view more (2006-09-08)

St. Jude finds signaling system that halts the growth of a childhood brain cancer
A discovery by St. Jude Children's Research Hospital scientists suggests a safer way to treat medulloblastoma, a rare but often fatal childhood brain tumor. The group found that one of the brain's signaling pathways inhibits the growth of the highly aggressive cancer cells.   view more (2008-03-17)

Statin plus cancer drug deliver combo punch to brain cancer cells
Building on newly discovered genetic threads in the rich tapestry of biochemical signals that cause cancer, a Johns Hopkins Kimmel Cancer Center team has dramatically killed brain cancer cells by blocking those signals with a statin and an experimental antitumor drug.   view more (2007-01-19)

Technique could speed new medulloblastoma drugs
Investigators at St. Jude Children's Research Hospital have developed a strategy to speed future development of more effective and less toxic treatments for medulloblastoma, a type of brain cancer.   view more (2006-04-18)

Childhood brain tumor traced to normal stem cells gone bad
An aggressive childhood brain tumor known as medulloblastoma originates in normal brain "stem" cells that turn malignant when acted on by a known mutant, cancer-causing oncogene, say researchers from Dana-Farber Cancer Institute and the University of California, San Francisco (UCSF).   view more (2008-08-12)

Protein protects embryonic stem cells' versatility and self-renewal
A protein known as REST blocks the expression of a microRNA that prevents embryonic stem cells from reproducing themselves and causes them to differentiate into specific cell types, scientists at The University of Texas M. D. Anderson Cancer Center report in the journal Nature.   view more (2008-03-24)

Cancer cells with a long breath: seeking the origin of brain tumors in children
Medulloblastoma is one of the most common and most malignant brain tumours among children and teenagers. These tumours grow very rapidly, and fifty percent of patients in the long term die from the condition.   view more (2008-08-13)

'Signature' of chromosome instability predicts cancer outcomes
Microscopic examination of tumor specimens cannot always predict a cancer's aggressiveness, leading to increased interest in molecular approaches to diagnosis.   view more (2006-08-21)

A pathway towards cures for Parkinson`s and cancer
Researchers studying the Hedgehog signaling pathway have identified small molecules that could form the foundations of exciting new treatments for Parkinson's disease and certain cancers. New research published in Journal of Biology - the open access journal for exceptional research - has... view more (2002-11-01)

Genetic parallels found between lung development and lung cancer
For over 100 years, biologists have speculated that cancer growth shares common features with embryonic development.   view more (2006-07-05)

St. Jude defines eye cancer gene's role in retinal development
A genetic discovery led by scientists at St. Jude Children's Research Hospital helps answer a long-standing mystery about the eyes of vertebrates, and may translate into a deeper understanding of how genes coordinate the complex process of eye formation and how a rare pediatric eye cancer... view more (2008-01-17)

Brain tumor researchers find their 'niche'
Brain tumors appear to arise from cancer stem cells (CSCs) that live within microscopic protective "niches" formed by blood vessels in the brain; and disrupting these niches is a promising strategy for eliminating the tumors and preventing them from re-growing.   view more (2007-01-17)

Cancer researchers describe gene that halts spread of aggressive childhood cancer
A team of cancer researchers has shown that a gene commonly lost during neuroblastoma tumor formation, one of the most aggressive cancers in babies and children, is in fact a "metastasis suppressor" gene.   view more (2006-01-05)

Certain anticancer agents could be harmful to patients with heart disease
A set of promising new anticancer agents could have unforeseen risks in individuals with heart disease, suggests research at Washington University School of Medicine in St. Louis.   view more (2008-06-24)

DNA repair in mammal embryos is a matter of timing
Investigators at St. Jude Children's Research Hospital have discovered that the cells of the developing nervous system of the mammalian embryo have an exquisite sense of timing when it comes to fixing broken chromosomes: the cells use one type of repair mechanism during the first half of... view more (2006-06-20)

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