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Molecular markers signal early metastases from ocular melanoma
Patients with melanoma of the eye are at risk for liver metastases, which are often not detected until they have turned into large, lethal tumors.   view more (2006-09-14)

History of nonmelanoma skin cancer is associated with increased risk for subsequent malignancies
Individuals with a history of nonmelanoma skin cancer (NMSC) are at increased risk for other cancers, according to a study published in the August 26 online issue of the Journal of the National Cancer Institute.   view more (2008-08-27)

Scientists harness diptheria toxin and interleukin 2 to help the immune system attack melanoma
Researchers investigating ways of prompting the immune system to recognise and kill tumour cells have found that a drug containing parts of the diptheria toxin appears to work well in patients with advanced melanoma (skin cancer).   view more (2006-11-09)

Beach vacations may increase future skin cancer risk in children
Vacationing at the shore led to a 5 percent increase in nevi (more commonly called "moles") among 7-year-old children, according to a paper published in Cancer Epidemiology, Biomarkers and Prevention, a journal of the American Association for Cancer Research.    view more (2009-02-03)

Researchers use embryonic model to reprogram malignant melanoma
Scientists at Northwestern University and the Stowers Institute for Medical Research have reprogrammed malignant melanoma cells to become normal melanocytes, or pigment cells, a development that may hold promise in treating of one of the deadliest forms of cancer.   view more (2006-02-28)

Melanomas may appear noticeably different than other moles
A preliminary study suggests that melanomas have a different appearance than other irregular skin moles (i.e., are "ugly ducklings"), according to a report in the January issue of Archives of Dermatology, one of the JAMA/Archives journals.   view more (2008-01-22)

Molecular differences between early and advanced melanomas could provide new drug targets
The cell-signaling molecule Akt is a primary trigger that leads malignant melanomas on the skin's surface to begin growing vertically beneath the skin and turn into deadly invasive cancers, scientists have found.   view more (2007-03-13)

NYU researchers demonstrate activity of mebendazole in metastatic melanoma
Researchers at the NYU Cancer Institute and the Ronald O. Perelman Department of Dermatology have identified mebendazole, a drug used globally to treat parasitic infections, as a novel investigational agent for the treatment of chemotherapy-resistant malignant melanoma.   view more (2008-08-07)

True cancer-causing genes revealed by new technique, say Stanford researchers
Often cancer research goes like this: study cancerous cells in a lab dish, find mutations that appear in many of the samples, develop drugs to target proteins made by the mutated genes, and voila, new chemotherapy drugs are born. Or at least that's the hope.   view more (2005-06-13)

Mouse model aids discovery of novel melanoma metastasis gene
Researchers from Dana-Farber Cancer Institute have identified a novel gene that facilitates the spread of malignant melanoma, a life-threatening skin cancer, using a technique they say can speed the discovery of hard-to-find cancer genes.   view more (2006-06-30)

Researchers identify mechanism used by gene to promote metastasis in human cancer cells
Virginia Commonwealth University Institute of Molecular Medicine and VCU Massey Cancer Center researchers have discovered how a gene, melanoma differentiation associated gene-9/syntenin (mda-9/syntenin), interacts with an important signaling protein to promote metastasis in human melanoma cells, a discovery that could one day lead to the... view more... (2008-09-30)

Study finds even healthcare professionals are sun-worshipers - despite knowing all about the risks of skin cancer
Prevention and education programmes have increased knowledge about the dangers of too much sun, but even healthcare professionals with high levels of awareness of the risk of skin cancer don't seem to be changing their behaviour, according to research presented at ECCO 12 - The European Cancer Conference today (Monday 22 September).   view more (2003-09-20)

Older Australians at risk of sun-related skin cancer death
A new Western Australian study has revealed the mortality from non-melanoma skin cancer (NMSC), commonly considered less dangerous than melanoma, is affecting older Australians at a worrying rate.   view more (2008-04-14)

NYU Langone Medical Center researchers find micro RNA plays a key role in melanoma metastasis
Scientists have long wondered how melanoma cells travel from primary tumors on the surface of the skin to the brain, liver and lungs, where they become more aggressive, resistant to therapy, and deadly.   view more (2009-02-10)

Prototype test for predicting clinical outcome for melanoma patients
Investigators from the Melbourne Center of the international Ludwig Institute for Cancer Research (LICR) and Pacific Edge Biotchnology Ltd today reported that they have developed a test to predict whether a patient will progress rapidly from Stage III melanoma to metastatic Stage IV cancer and death.   view more (2008-08-15)

A new measure for the malignancy of melanoma
Every tumor, starting from a size of a few millimeters, depends on a supply of nutrients and oxygen. Therefore, using special growth factors, it induces vascular wall cells of neighboring blood vessels to sprout new capillaries in order to get connected to the blood circulation.   view more (2009-03-12)

Key mechanism found that promotes spread of malignant melanoma
Researchers at Northwestern University have discovered a key signaling mechanism that may promote the ability of highly aggressive malignant melanoma cells to metastasize, or spread from a primary tumor to distant sites within the body.   view more (2005-11-01)

Researchers discover why melanoma is so malignant
About 60,000 Americans will be diagnosed with melanoma this year, says the American Cancer Society, and 10,000 of those cases will be fatal.   view more (2005-09-06)

Marathon runners may be at increased risk for skin cancer
In an Austrian study, marathon runners had more atypical moles and other skin lesions suggestive of a risk for skin cancer than did a comparison group of age- and sex-matched controls.   view more (2006-11-21)

Protein amplification in melanoma is possible drug target
Researchers have pinpointed specific gene and protein over-production in metastatic melanoma, pointing the way to a possible new drug target, according to a study published in Nature July 7.   view more (2005-07-11)
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