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NIST membrane model may unlock secrets of early-stage Alzheimer's
Researchers at the National Institute of Standards and Technology (NIST) and three collaborating institutions are using a new laboratory model of the membrane surrounding neurons in the brain to study how a protein long suspected of a role in early-stage Alzheimer's disease actually impairs a neuron's structure and function. view more (2008-07-24)
New structure discovered in butterfly ears
A clever structure in the ear of a tropical butterfly that potentially makes it able to distinguish between high and low pitch sounds has been discovered by scientists from the University of Bristol. view more (2009-10-22)
Prions link cholesterol to neurodegeneration
Prion infection of neurons increases the free cholesterol content in cell membranes. A new study published in the online open access journal BMC Biology suggests that disturbances in membrane cholesterol may be the mechanism by which prions cause neurodegeneration and could point to a role for cholesterol in other neurodegenerative diseases. view more (2008-02-12)
Why does aspirin increase the susceptibility of Helicobacter pylori to antimicrobials?
Resent studies reported that aspirin inhibited the growth of H. pylori in a dose-dependent manner and significantly affected the activity of virulence factors of H. pylori. view more (2009-03-03)
New 'self-exploding' microcapsules could take sting out of drug delivery
Belgian chemists have developed "self-exploding" microcapsules that could one day precisely release drugs and vaccines inside the human body weeks or even months after injection. view more (2006-01-04)
Lamin A/C deficiency is 'unnerving'
Mutations in the nuclear intermediate filament lamin A/C (LMNA) gene are associated with Emery-Dreifuss muscular dystrophy, but cause the disease by unknown mechanisms. Méjat et al. show that one mechanism involves the disruption of neuromuscular junctions. view more (2009-01-05)
Findings could improve fuel cell efficiency
A new type of membrane based on tiny iron particles appears to address one of the major limitations exhibited by current power-generating fuel cell technology. view more (2008-03-20)
Scientists reveal fine detail of cell`s energy machinery
A molecular pump that helps to keep cells flush with energy has been visualised by scientists at Imperial College, London. The structure of the pump, a key enzyme in bacterial respiration, reveals for the first time one of the molecular mechanisms that underpins cellular respiration, and confirms a Nobel Prize-winning theory proposed over 40... view more... (2002-03-05)
Saving Cells - Safer Method for Filtering Sensitive Biological Products
For many years, engineers have worked to efficiently filter valuable bio-process products on an industrial economic scale. The challenge has been to push rates up without incurring high shear rates and resultant cell lysis, which would cause loss of yield. High shear can destroy delicate and valuable biological materials such as proteins, blood,... view more... (2004-07-23)
Structural mechanism of the E. coli drug efflux pump AcrB
In a new study published online in the open access journal PLoS Biology, Gaby Sennhauser, Marcus Gruetter, and colleagues use structural biology techniques to probe the molecular mechanisms of the major drug efflux pump in E. coli AcrB. view more (2006-12-27)
New material brings hydrogen fuel, cheaper petrochemicals closer to reality
A rubbery material that can purify hydrogen efficiently in its most usable form for fuel cells and oil refining has been developed by a chemical engineering group at The University of Texas at Austin. view more (2006-02-03)
Artificial membranes can reveal biological weapons
Today there is a great need for portable equipment that can quickly detect chemical and biological weapons such as nerve gases, viruses, bacteria, and toxins. In a new dissertation the Swedish researcher Inga Gustafsson shows that artificial membranes can be used for this purpose in future biosensors. Biosensors have already... view more... (2004-01-16)
New nanoparticles could revolutionize therapeutic drug discovery
A revolutionary new protein stabilisation technique has been developed by scientists funded by the Biotechnology and Biological Sciences Research Council (BBSRC) which could lead to 30 per cent more proteins being available as potential targets for drug development - opening up exciting possibilities in drug discovery. view more (2009-06-26)
Cholesterol modulates sorting of CEA -- implications for inflammatory bowel disease
In polarized Caco-2 cells, cholesterol was depleted by a combination of synthesis inhibition and plasma membrane extraction with complexing agents. view more (2008-04-30)
Fruit fly helps identify protein critical to eggshell formation that may be pesticide target
The common fruit fly circling your week-old peach has helped scientists zero in on a protein critical to the insect's eggshell formation. view more (2008-05-30)
Nanoresearchers challenge dogma in protein transportation in cells
New data on signalling proteins, called G proteins, may prove important in fighting diseases such as cardiovascular, neurodegenerative disorders, and cancer. view more (2009-09-22)
Jefferson scientists uncover new clues to how crucial molecular gatekeepers work
One of the biggest mysteries in molecular biology is exactly how ion channels - tiny protein pores through which molecules such as calcium and potassium flow in and out of cells - operate. view more (2005-10-12)
New 'control knobs' for stem cells identified
Natural changes in voltage that occur across the membrane of adult human stem cells are a powerful controlling factor in the process by which these stem cells differentiate, according to research published by Tufts University scientists. view more (2008-12-04)
Argonne breakthrough may revolutionize ethylene production
A new environmentally friendly technology created by scientists at the U.S. Department of Energy's (DOE) Argonne National Laboratory may revolutionize the production of the world's most commonly produced organic compound, ethylene. view more (2008-02-06)
Methane bacteria possess pressure valve
Microbiologists from the University of Nijmegen have discovered that a methane-forming archaeabacterium sometimes deliberately allows hydrogen ions to leak out of its cell. At high hydrogen concentrations in particular, the cell membrane works as a sort of pressure valve. The waste of energy seems to be of vital importance for the microorganism.... view more... (2002-10-24)
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