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New study resolves the mysterious origin of Merkel cells
A new study resolves a 130-year-old mystery over the developmental origin of specialized skin cells involved in touch sensation.   view more (2009-09-28)

Case Western Reserve University discovers Merkel cell originates from skin, not the neural crest
Case Western Reserve University School of Medicine assistant professor of pediatrics, neurosciences and otolaryngology, Stephen M. Maricich, M.D., Ph.D., and his team found that Merkel cells originate in the skin, not the neural crest lineage, as previously speculated.   view more (2009-10-05)

Pitt research indicates new virus is culprit, not bystander, in deadly skin cancer
University of Pittsburgh scientists are uncovering more evidence that a virus they recently discovered is the cause of Merkel cell carcinoma, an aggressive and deadly form of skin cancer.   view more (2008-09-23)

Can pathological techniques help identify primary colorectal signet ring cell carcinoma?
Primary colorectal signet ring cell carcinoma is a rare but distinctive malignancy of the large bowel. More than 96% of signet ring cell carcinomas arise in the stomach, with the rest arising from other primary organs.   view more (2008-05-21)

Gastric cancer with 3 pathological features
Primary carcinoma of the stomach is almost always adenocarcinoma or signet ring cell carcinoma and there are few reports of choriocarcinoma or neuroendocrine cell carcinoma.   view more (2008-09-18)

A potential molecular target for biotherapy esophageal squamous cell carcinomas
The cadherin superfamily has a correlate relationship with the invasion and metastasis of carcinoma.   view more (2009-02-19)

The small cell neuroendocrine carcinoma of the ampulla of vater
Ampullary small cell neuroendocrine carcinoma is extremely rare and has only been documented in few case reports and retrospective study. The patients with ampullary small cell neuroendocrine carcinoma usually presented after the age of 60 years, and a male predilection was observed.   view more (2008-09-25)

Study Examines Role of Helicobacter Pylori in Esophageal Cancer Development
Infection with bacteria that can cause peptic ulcers and distal stomach cancer may be associated with a reduced risk of a type of esophageal cancer called adenocarcinoma, according to a study in the March 3 issue of the Journal of the National Cancer Institute. However, that same study found that people infected with the bacteria, called... view more... (2004-03-03)

Dental researchers confirm microRNAs as biomarkers for oral cancer detection
A new study published by researchers at the UCLA School of Dentistry substantiates the effectiveness of measuring the microRNAs present in saliva to detect oral squamous cell carcinoma.   view more (2009-08-26)

A potential route for human tumor gene therapy
The type 1 Na+/H+ exchanger (NHE1) is a transmembrane protein found in all eukaryotic cells. One of its functions is to evacuate excessive H+ in the cytoplasm by means of Na+-H+ exchange, resulting in stable intracellular pH value.   view more (2008-05-21)

Older Australians at risk of sun-related skin cancer death
A new Western Australian study has revealed the mortality from non-melanoma skin cancer (NMSC), commonly considered less dangerous than melanoma, is affecting older Australians at a worrying rate.   view more (2008-04-14)

Which is accurate, CT or MRI?
Paraaortic lymph node metastasis in patients with pancreatico-biliary carcinoma has been reported as a definite predictor of early recurrence and shorter survival term.   view more (2008-05-21)

Incidence of nonmelanoma skin cancer on the rise among young adults
A new study from Minnesota finds the incidence of nonmelanoma skin cancer increasing among men and women under the age of 40, according to an article in the August 10 issue of JAMA.   view more (2005-08-10)

Angiotensin inhibitors and receptor blockers linked to lower risk of nonmelanoma skin cancer
The use of angiotensin-converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs) was associated with a reduced risk of basal cell or squamous cell skin cancers in U.S. veterans, researchers report in the August 26 online issue of the Journal of the National Cancer Institute.   view more (2008-08-27)

Yes-associated protein: Early diagnosis of gastric carcinoma
Yes-associated protein (YAP) is a type of cellular adaptor protein and transcriptional co-activator.   view more (2009-09-16)

Ultraviolet B light exposure associated with increased risk of skin cancer
A decreased ability to repair chromosomal damage caused by exposure to ultraviolet B (UV-B) radiation in test tubes may be associated with an increased risk of the common skin cancers basal cell carcinoma and squamous cell carcinoma, but not of melanoma.   view more (2005-12-21)

A feasible, simple and convenient model for study of rectal carcinoma
The method of building a rabbit rectal VX2 carcinoma model by injecting the cell suspension of VX2 cells into the wall of the rectum guided by X-ray fluoroscopy is feasible.   view more (2009-05-13)

A potential targets for the prevention or treatment of esophageal carcinoma
Expression of Livin in fresh esophageal cancer tissues was detected by immunohistochemistry (IHC), Western blotting and reverse transcriptase-polymerase chain reaction (RT-PCR), VEGF by Its correlation Western blotting and RT-PCR.   view more (2008-10-29)

How is H pylori adhesion to gastric cells associated with MUC1 mucin VNTR size?
The Gram negative bacterium H pylori is involved in the pathogenesis of several gastrointestinal diseases, ultimately leading to gastric carcinoma. Adhesion of the bacteria to the gastric mucosa is an essential step for colonization and infection.   view more (2008-03-19)

Is the spleen able to prohibit tumor cell proliferation?
Primary and metastatic tumors of the spleen are described as unusual, excluding involvement by lymphoma. Indeed, isolated splenic metastasis from colorectal carcinoma is not a common occurrence. Its rareness has been hypothetically explained by several characteristics of the spleen, such as anatomical, histological and immunological features.   view more (2007-10-17)
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